Article
Chemistry, Analytical
Morteza Hosseini, Elahe Hashemian, Foad Salehnia, Mohammad Reza Ganjali
Summary: In this work, a turn-on electrochemiluminescence (ECL) sensor based on graphite carbon nitride (g-C3N4) was developed for sensitive quantification of melatonin. The sensor demonstrated a wide linear response range, low detection limit, and successful application in the detection of melatonin in human saliva samples.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Lichan Chen, Mengxi Zhu, Xiaomeng Zheng, Yuting Zhong, Xiaodi Zhu
Summary: This paper summarizes the advances in nCN ECL and presents various strategies to improve its performance, including intensity enhancement, stability improvement, lowering potential, tailoring wavelength, and extending duration. The strategies are classified into formation of functional nanocomposites and molecular engineering. In addition, the current challenges and future possibilities are discussed.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2023)
Article
Biochemical Research Methods
Yuyang Lu, Shu Han, Yachao Xi, Shuhan Yang, Tao Zhu, Binhan Niu, Fang Li
Summary: In this study, TiO2 nanoparticles modified graphitic carbon nitride were prepared, exhibiting potential-resolved multicolor electrochemiluminescence (ECL) emission. The synthesized composite showed dual-peak ECL emission under cyclic voltammetry scanning, allowing for sensitive quantitative detection of rutin. This work provides a simple method to broaden the potential applications of g-C3N4-based nanocomposites for ECL imaging sensing and light-emitting devices.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Lichan Chen, Hongzhi Guo, Libing Tian, Shu-Feng Zhou
Summary: In this study, graphitic carbon nitride (g-CN) was molecularly engineered with phenyl groups to enhance its electrical conductivity. The resulting Ph-CN nanosheets (Ph-CNNS) exhibited stable and strong cathodic electrochemiluminescence (ECL) emission, which was used to develop an ECL immunosensor for the detection of cardiac Troponin I (cTnI). The ECL immunosensor showed promising performance in terms of linear response, detection limit, specificity, reproducibility, and long-term stability.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Rui Zou, Yanjun Lin, Chao Lu
Summary: This study developed a nitrogen vacancy (NV) engineering strategy to improve the electrochemiluminescence (ECL) performance of graphitic carbon nitride (CN), achieving amplification in ECL intensity and stability. NVs were found to facilitate electron transfer and inhibit electrode passivation in CN-NVs.
ANALYTICAL CHEMISTRY
(2021)
Article
Electrochemistry
Xiaolong Fu, Ju Huang, Xiaojing Lai, Jiefeng Rong, Guomin Qi, Zhenyu Lin, Fengfu Fu, Yongqiang Dong
Summary: Electrochemiluminescence (ECL) of graphitic carbon nitride nanosheets (CNNSs) has gained extensive interest, but the poor ECL stability of CNNSs has hindered its application. This study investigates the mechanism affecting ECL stability and proposes effective methods to improve it.
ELECTROCHIMICA ACTA
(2023)
Article
Nanoscience & Nanotechnology
Xiaolong Fu, Zhihong Liu, Yajie Jiao, Lichan Chen, Zhenyu Lin, Fengfu Fu, Yongqiang Dong
Summary: A facile strategy of enhancing the fluorescence activity of graphitic carbon nitride nanosheets (CNNSs) is developed by alkali-mediated passivation of the surface defect states, resulting in a significant improvement in FL quantum yields.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Yajie Jiao, Rongjing Hu, Qian Wang, Fengfu Fu, Lichan Chen, Yongqiang Dong, Zhenyu Lin
Summary: The effects of defect states on the fluorescence and electrochemiluminescence properties of graphite phase carbon nitride were systematically investigated for the first time. The study found that decreasing the density of defect states can increase the fluorescence quantum yield, while increasing the density of defect states can make the fluorescence spectra red shift. Additionally, increasing the density of CN-defect states and decreasing the density of C-defect states are important to improve the electrochemiluminescence activity.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Analytical
Seyyed Mehdi Khoshfetrat, Pegah Hashemi, Abbas Afkhami, Ali Hajian, Hasan Bagheri
Summary: The study introduces a strategy using high catalytic activity artificial enzyme mimics for detecting biomarkers, successfully achieving detection of PSA with high sensitivity.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Physical
S. Saranya, P. N. Deepa
Summary: A composite material of Nickel with oxidized g-C3N4 (Oxi-g-C3N4) was successfully synthesized via hydrothermal treatment, showing a porous rod-like morphology and good fluorescence performance. The electrode modified with this composite material exhibited excellent electrocatalytic properties and could detect the highly carcinogenic organophosphate pesticide chlorpyrifos.
SURFACES AND INTERFACES
(2022)
Review
Chemistry, Inorganic & Nuclear
Ritu Malik, Nirav Joshi, Vijay K. Tomer
Summary: The review summarizes the advancements and applications of graphitic carbon nitride (g-C3N4) in sensing, photocatalysis, electromagnetic shielding, and energy storage devices. It highlights the lack of in-depth research on g-CN based sensors and their transduction principles, sensitivity/selectivity issues, and provides insights into their potential as a new sensing platform.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Green & Sustainable Science & Technology
Varsha Raj Govindaraju, Kempahanumakkagari Sureshkumar, Thippeswamy Ramakrishnappa, Sreeramareddygari Muralikrishna, Devaramani Samrat, Ranjith Krishna Pai, Vanish Kumar, Kumar Vikrant, Ki-Hyun Kim
Summary: Graphitic carbon nitride (g-C3N4) has great potential in photocatalytic applications, but its electrochemical applicabilities are limited by low electrical conductivity. Enhancing electrocatalytic activity through doping and alloying can unlock greater potential for g-C3N4 in environment and energy sectors in the future.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Chemistry, Applied
Aniruddha Molla, Ji Ho Youk
Summary: Nanocomposites of graphitic carbon nitride supported on graphene oxide (g-C3N4/GO) were synthesized using the mechanochemical method, and their excellent adsorption performance for methylene blue was demonstrated. The nanocomposite exhibited high sorption capacity, good reusability, and spontaneous sorption process, mainly attributed to physisorption.
Article
Chemistry, Analytical
Ying Gu, Yuanling Hu, Fuyuan Zhang, Lunzhao Yi, Ying Shang, Dabing Ren, Zhenhua Ge
Summary: A glucose sensor was developed using synthetic cyclic peptides as recognition receptors and Au nanoparticles for ECL enhancement. The sensor demonstrated specific glucose capture and detection, with good sensitivity and a low detection limit.
Article
Chemistry, Physical
Petr Praus
Summary: The electronegativity values of graphitic carbon nitride (g-C3N4) are complex and vary based on different calculation methods, ranging from 4.64-4.77eV and 3.79-4.62eV. Experimental verification is recommended for accurately determining the conduction band potentials of g-C3N4.
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)