The origin of DCs and capacity for immunologic tolerance in central and peripheral tissues

Broad and Largely Concordant Molecular Changes Characterize Tolerogenic and Immunogenic Dendritic Cell Maturation in Thymus and Periphery

(2016) Laurence Ardouin et al.   IMMUNITY

Expansion and Activation of CD103 + Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition

(2016) Hélène Salmon et al.   IMMUNITY

Duality at the gate: Skin dendritic cells as mediators of vaccine immunity and tolerance

(2016) Christopher J Nirschl et al.   Human Vaccines & Immunotherapeutics

Tolerogenic IDO+ Dendritic Cells Are Induced by PD-1-Expressing Mast Cells

(2016) Cecilia Pessoa Rodrigues et al.   Frontiers in Immunology

Efficacy and safety of CDX-301, recombinant human Flt3L, at expanding dendritic cells and hematopoietic stem cells in healthy human volunteers

(2015) N Anandasabapathy et al.   BONE MARROW TRANSPLANTATION

Homeostatic NF-κB Signaling in Steady-State Migratory Dendritic Cells Regulates Immune Homeostasis and Tolerance

(2015) Myriam Baratin et al.   IMMUNITY

Klf4 Expression in Conventional Dendritic Cells Is Required for T Helper 2 Cell Responses

(2015) Roxane Tussiwand et al.   IMMUNITY

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

(2015) Stefani Spranger et al.   NATURE

Functional Specialization of Skin Dendritic Cell Subsets in Regulating T Cell Responses

(2015) Björn E. Clausen et al.   Frontiers in Immunology

Tolerogenic dendritic cells and their applications in transplantation

(2014) Haibin Li et al.   Cellular & Molecular Immunology

Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming

(2014) M. Dalod et al.   EMBO JOURNAL

Classical Flt3L-dependent dendritic cells control immunity to protein vaccine

(2014) Niroshana Anandasabapathy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD11b+ Migratory Dendritic Cells Mediate CD8 T Cell Cross-Priming and Cutaneous Imprinting after Topical Immunization

(2014) Suzanne T. Nizza et al.   PLoS One

Induction of Antigen-Specific Immunity with a Vaccine Targeting NY-ESO-1 to the Dendritic Cell Receptor DEC-205

(2014) M. V. Dhodapkar et al.   Science Translational Medicine

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

Molecular Control of Steady-State Dendritic Cell Maturation and Immune Homeostasis

(2013) Gianna Elena Hammer et al.   Annual Review of Immunology

FLT3L and Plerixafor Combination Increases Hematopoietic Stem Cell Mobilization and Leads to Improved Transplantation Outcome

(2013) Shun He et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Mast cells suppress murine GVHD in a mechanism independent of CD4+CD25+ regulatory T cells

(2013) D. B. Leveson-Gower et al.   BLOOD

Current status of interleukin-10 and regulatory T-cells in cancer

(2013) Kristen L. Dennis et al.   CURRENT OPINION IN ONCOLOGY

Origins and Functional Specialization of Macrophages and of Conventional and Monocyte-Derived Dendritic Cells in Mouse Skin

(2013) Samira Tamoutounour et al.   IMMUNITY

IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses

(2013) Andreas Schlitzer et al.   IMMUNITY

Fas Signal Promotes the Immunosuppressive Function of Regulatory Dendritic Cells via the ERK/β-Catenin Pathway

(2013) Cheng Qian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flt3L Dependence Helps Define an Uncharacterized Subset of Murine Cutaneous Dendritic Cells

(2013) Shamim A. Mollah et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens

(2013) Annemieke de Jong et al.   NATURE IMMUNOLOGY

Type 1 Regulatory T Cells and Regulatory B Cells Induced by Tolerogenic Dendritic Cells

(2013) R. Volchenkov et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Regulatory dendritic cells program B cells to differentiate into CD19hiFc IIbhi regulatory B cells through IFN-  and CD40L

(2012) L. Qian et al.   BLOOD

GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells

(2012) Melanie Greter et al.   IMMUNITY

Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells

(2012) Muzlifah Haniffa et al.   IMMUNITY

Zbtb46expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages

(2012) Ansuman T. Satpathy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage

(2012) Matthew M. Meredith et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac–derived macrophages

(2012) Guillaume Hoeffel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD64 Expression Distinguishes Monocyte-Derived and Conventional Dendritic Cells and Reveals Their Distinct Role during Intramuscular Immunization

(2012) C. Langlet et al.   JOURNAL OF IMMUNOLOGY

Compensatory dendritic cell development mediated by BATF–IRF interactions

(2012) Roxane Tussiwand et al.   NATURE

Transcriptional Regulation of Dendritic Cell Diversity

(2012) Michaël Chopin et al.   Frontiers in Immunology

The Role of Coinhibitory Signaling Pathways in Transplantation and Tolerance

(2012) Martina M. McGrath et al.   Frontiers in Immunology

Id2 expression delineates differential checkpoints in the genetic program of CD8α+and CD103+dendritic cell lineages

(2011) Jacob T Jackson et al.   EMBO JOURNAL

Skin-Resident Murine Dendritic Cell Subsets Promote Distinct and Opposing Antigen-Specific T Helper Cell Responses

(2011) Botond Z. Igyártó et al.   IMMUNITY

Mast Cells Condition Dendritic Cells to Mediate Allograft Tolerance

(2011) Victor C. de Vries et al.   IMMUNITY

Notch2 Receptor Signaling Controls Functional Differentiation of Dendritic Cells in the Spleen and Intestine

(2011) Kanako L. Lewis et al.   IMMUNITY

Dendritic cell control of tolerogenic responses

(2011) Santhakumar Manicassamy et al.   IMMUNOLOGICAL REVIEWS

Tolerogenic dendritic cells and their potential applications

(2011) Jim Hu et al.   IMMUNOLOGY

Developing immunologic tolerance for transplantation at the fetal stage

(2011) Hugo Mendieta-Zerón   Immunotherapy

The Novel Costimulatory Programmed Death Ligand 1/B7.1 Pathway Is Functional in Inhibiting Alloimmune Responses In Vivo

(2011) J. Yang et al.   JOURNAL OF IMMUNOLOGY

Pulmonary CD103+ dendritic cells prime Th2 responses to inhaled allergens

(2011) H Nakano et al.   Mucosal Immunology

Tolerogenic dendritic cells and their role in transplantation

(2011) Mohamed Ezzelarab et al.   SEMINARS IN IMMUNOLOGY

Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development

(2010) E. Martin-Gayo et al.   BLOOD

Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas

(2010) Cheolho Cheong et al.   CELL

Intracellular mechanisms of antigen cross presentation in dendritic cells

(2010) Sebastian Amigorena et al.   CURRENT OPINION IN IMMUNOLOGY

Negative vaccination by tolerogenic dendritic cells in organ transplantation

(2010) Marcelo Hill et al.   Current Opinion in Organ Transplantation

Immunogenic Versus Tolerogenic Dendritic Cells: A Matter of Maturation

(2010) Roland Tisch   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Peripheral CD103+dendritic cells form a unified subset developmentally related to CD8α+conventional dendritic cells

(2010) Brian T. Edelson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

On/Off TLR Signaling Decides Proinflammatory or Tolerogenic Dendritic Cell Maturation upon CD1d-Mediated Interaction with Invariant NKT Cells

(2010) S. Caielli et al.   JOURNAL OF IMMUNOLOGY

TGF-  Is Required To Maintain the Pool of Immature Langerhans Cells in the Epidermis

(2010) J. M. Kel et al.   JOURNAL OF IMMUNOLOGY

Sensing the outside world: TSLP regulates barrier immunity

(2010) Steven F Ziegler et al.   NATURE IMMUNOLOGY

The concerted action of GM-CSF and Flt3-ligand on in vivo dendritic cell homeostasis

(2009) D. Kingston et al.   BLOOD

Dendritic cell homeostasis

(2009) M. Merad et al.   BLOOD

Interferon- -triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells

(2009) B. Jurgens et al.   BLOOD

Inflammatory Monocytes Facilitate Adaptive CD4 T Cell Responses during Respiratory Fungal Infection

(2009) Tobias M. Hohl et al.   Cell Host & Microbe

HIV gag protein is efficiently cross-presented when targeted with an antibody towards the DEC-205 receptor in Flt3 ligand-mobilized murine DC

(2009) Leonia Bozzacco et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Origin of the Lamina Propria Dendritic Cell Network

(2009) Milena Bogunovic et al.   IMMUNITY

A Recurrent Network Involving the Transcription Factors PU.1 and Gfi1 Orchestrates Innate and Adaptive Immune Cell Fates

(2009) Chauncey J. Spooner et al.   IMMUNITY

The origin and development of nonlymphoid tissue CD103+DCs

(2009) Florent Ginhoux et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD207+CD103+dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

(2009) Sandrine Henri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

(2009) Guillaume Darrasse-Jèze et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

(2009) Caspar Ohnmacht et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tryptophan Deprivation Induces Inhibitory Receptors ILT3 and ILT4 on Dendritic Cells Favoring the Induction of Human CD4+CD25+ Foxp3+ T Regulatory Cells

(2009) M. Brenk et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cells Secrete the Immunosuppressive HLA-G Molecule upon CTLA4-Ig Treatment: Implication in Human Renal Transplant Acceptance

(2009) R. Bahri et al.   JOURNAL OF IMMUNOLOGY

Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses

(2009) Hideki Nakano et al.   NATURE IMMUNOLOGY

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

(2009) Sammy Bedoui et al.   NATURE IMMUNOLOGY

Murine epidermal Langerhans cells and langerin-expressing dermal dendritic cells are unrelated and exhibit distinct functions

(2009) K. Nagao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Books Received

(2009)   SCIENCE

Transcription Factor E2-2 Is an Essential and Specific Regulator of Plasmacytoid Dendritic Cell Development

(2008) Babacar Cisse et al.   CELL

Generation of therapeutic dendritic cells and regulatory T cells for preventing allogeneic cardiac graft rejection

(2008) Xusheng Zhang et al.   CLINICAL IMMUNOLOGY

Cytokine-producing B lymphocytes—key regulators of immunity

(2008) Frances E Lund   CURRENT OPINION IN IMMUNOLOGY

Thymic Stromal Lymphopoietin and Thymic Stromal Lymphopoietin-Conditioned Dendritic Cells Induce Regulatory T-Cell Differentiation and Protection of NOD Mice Against Diabetes

(2008) G. Besin et al.   DIABETES

Development of human plasmacytoid dendritic cells depends on the combined action of the basic helix-loop-helix factor E2-2 and the Ets factor Spi-B

(2008) Maho Nagasawa et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

FLT3 inhibitors for the treatment of autoimmune disease

(2008) Katharine A Whartenby et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Constitutive Crosspresentation of Tissue Antigens by Dendritic Cells Controls CD8+ T Cell Tolerance In Vivo

(2008) Nancy Luckashenak et al.   IMMUNITY

Mechanisms and Consequences of Dendritic Cell Migration

(2008) David Alvarez et al.   IMMUNITY

The Signal Transducer STAT5 Inhibits Plasmacytoid Dendritic Cell Development by Suppressing Transcription Factor IRF8

(2008) Eiji Esashi et al.   IMMUNITY

A Two-Step Process for Thymic Regulatory T Cell Development

(2008) Chan-Wang Joaquim Lio et al.   IMMUNITY

The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues

(2008) Claudia Waskow et al.   NATURE IMMUNOLOGY

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

(2008) Qizhi Tang et al.   NATURE IMMUNOLOGY

TGF-  signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis

(2008) Y. Laouar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic cells in the thymus contribute to T-regulatory cell induction

(2008) A. I. Proietto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE

Oral tolerance: intestinal homeostasis and antigen-specific regulatory T cells

(2008) Noriko M. Tsuji et al.   TRENDS IN IMMUNOLOGY