Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases
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Title
Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases
Authors
Keywords
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Journal
Science Translational Medicine
Volume 8, Issue 360, Pages 360ra135-360ra135
Publisher
American Association for the Advancement of Science (AAAS)
Online
2016-10-13
DOI
10.1126/scitranslmed.aaf5219
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Note: Only part of the references are listed.- Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer
- (2016) S. R. Hingorani et al. CLINICAL CANCER RESEARCH
- Macrophages and Therapeutic Resistance in Cancer
- (2015) Brian Ruffell et al. CANCER CELL
- Myeloid Cells as Targets for Therapy in Solid Tumors
- (2015) Tiziana Cotechini et al. CANCER JOURNAL
- Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer
- (2015) C. J. Whatcott et al. CLINICAL CANCER RESEARCH
- CXCR4 inhibition in tumor microenvironment facilitates anti-programmed death receptor-1 immunotherapy in sorafenib-treated hepatocellular carcinoma in mice
- (2015) Yunching Chen et al. HEPATOLOGY
- Compression of Pancreatic Tumor Blood Vessels by Hyaluronan Is Caused by Solid Stress and Not Interstitial Fluid Pressure
- (2014) Vikash P. Chauhan et al. CANCER CELL
- Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia
- (2014) Rakesh K. Jain CANCER CELL
- Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy
- (2014) Mara H. Sherman et al. CELL
- Tumor-Associated Macrophages: From Mechanisms to Therapy
- (2014) Roy Noy et al. IMMUNITY
- Tumor-Associated Hyaluronan Limits Efficacy of Monoclonal Antibody Therapy
- (2014) N. C. Singha et al. MOLECULAR CANCER THERAPEUTICS
- Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
- (2013) Gregg L. Semenza Annual Review of Pathology-Mechanisms of Disease
- Collagen Signaling Enhances Tumor Progression after Anti-VEGF Therapy in a Murine Model of Pancreatic Ductal Adenocarcinoma
- (2013) K. Y. Aguilera et al. CANCER RESEARCH
- Coevolution of Solid Stress and Interstitial Fluid Pressure in Tumors During Progression: Implications for Vascular Collapse
- (2013) Triantafyllos Stylianopoulos et al. CANCER RESEARCH
- A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response
- (2013) Ning Ding et al. CELL
- Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal-derived factor 1 alpha/C-X-C receptor type 4 axis and myeloid differentiation antigen-positive myeloid cell infiltration in mice
- (2013) Yunching Chen et al. HEPATOLOGY
- Deciphering and Reversing Tumor Immune Suppression
- (2013) Greg T. Motz et al. IMMUNITY
- Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer
- (2013) Jonathan Welti et al. JOURNAL OF CLINICAL INVESTIGATION
- Normalizing Tumor Microenvironment to Treat Cancer: Bench to Bedside to Biomarkers
- (2013) Rakesh K. Jain JOURNAL OF CLINICAL ONCOLOGY
- Strategies for advancing cancer nanomedicine
- (2013) Vikash P. Chauhan et al. NATURE MATERIALS
- Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment
- (2013) A Casazza et al. ONCOGENE
- Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
- (2012) Paolo P. Provenzano et al. CANCER CELL
- Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
- (2012) Douglas Hanahan et al. CANCER CELL
- Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
- (2012) Michael A Jacobetz et al. GUT
- Bevacizumab-Based Therapies in the First-Line Treatment of Metastatic Colorectal Cancer
- (2012) J. H. Strickler et al. ONCOLOGIST
- Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy
- (2012) Y. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Origins of tumor-associated macrophages and neutrophils
- (2012) V. Cortez-Retamozo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors
- (2012) T. Stylianopoulos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Therapeutic Targeting of Hyaluronan in the Tumor Stroma
- (2012) Anne Kultti et al. Cancers
- Molecular Pathways: Hypoxia Response in Immune Cells Fighting or Promoting Cancer
- (2011) Asis Palazón et al. CLINICAL CANCER RESEARCH
- Molecular mechanisms and clinical applications of angiogenesis
- (2011) Peter Carmeliet et al. NATURE
- Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors
- (2011) B. Diop-Frimpong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Delivery of Molecular and Nanoscale Medicine to Tumors: Transport Barriers and Strategies
- (2011) Vikash P. Chauhan et al. Annual Review of Chemical and Biomolecular Engineering
- Targeting the Tumor Microenvironment in Cancer: Why Hyaluronidase Deserves a Second Look
- (2011) C. J. Whatcott et al. Cancer Discovery
- Impact of bevacizumab on functional recovery and histology of the liver after resection of colorectal metastases
- (2010) D. A. Wicherts et al. BRITISH JOURNAL OF SURGERY
- Hyaluronan in human malignancies
- (2010) R.K. Sironen et al. EXPERIMENTAL CELL RESEARCH
- Enzymatic Depletion of Tumor Hyaluronan Induces Antitumor Responses in Preclinical Animal Models
- (2010) C. B. Thompson et al. MOLECULAR CANCER THERAPEUTICS
- Delivering nanomedicine to solid tumors
- (2010) Rakesh K. Jain et al. Nature Reviews Clinical Oncology
- Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis
- (2009) Karlin Raja Karlmark et al. HEPATOLOGY
- Gaussia luciferase reporter assay for monitoring biological processes in culture and in vivo
- (2009) Bakhos A Tannous Nature Protocols
- Secreted Gaussia Luciferase as a Biomarker for Monitoring Tumor Progression and Treatment Response of Systemic Metastases
- (2009) Euiheon Chung et al. PLoS One
- Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites
- (2009) F. K. Swirski et al. SCIENCE
- Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
- (2008) Scott L. Friedman PHYSIOLOGICAL REVIEWS
- In vivo diffusion of lactoferrin in brain extracellular space is regulated by interactions with heparan sulfate
- (2008) R. G. Thorne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hyaluronan in human tumors: Pathobiological and prognostic messages from cell-associated and stromal hyaluronan
- (2008) Raija H. Tammi et al. SEMINARS IN CANCER BIOLOGY
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