Comment on “SUMO deconjugation is required for arsenic-triggered ubiquitylation of PML”

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase

(2015) Laurent Cappadocia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SUMO deconjugation is required for arsenic-triggered ubiquitylation of PML

(2015) Domenico Fasci et al.   Science Signaling

System-wide identification of wild-type SUMO-2 conjugation sites

(2015) Ivo A. Hendriks et al.   Nature Communications

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase

(2015) Laurent Cappadocia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SUMO deconjugation is required for arsenic-triggered ubiquitylation of PML

(2015) Domenico Fasci et al.   Science Signaling

SUMO Chain-Induced Dimerization Activates RNF4

(2014) Alejandro Rojas-Fernandez et al.   MOLECULAR CELL

Activation of a promyelocytic leukemia–tumor protein 53 axis underlies acute promyelocytic leukemia cure

(2014) Julien Ablain et al.   NATURE MEDICINE

Poly-Small Ubiquitin-like Modifier (PolySUMO)-binding Proteins Identified through a String Search

(2012) Huaiyu Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PML/RARA Oxidation and Arsenic Binding Initiate the Antileukemia Response of As2O3

(2010) Marion Jeanne et al.   CANCER CELL

Arsenic Trioxide Controls the Fate of the PML-RAR  Oncoprotein by Directly Binding PML

(2010) X. W. Zhang et al.   SCIENCE

Ubc9 Sumoylation Regulates SUMO Target Discrimination

(2008) Puck Knipscheer et al.   MOLECULAR CELL

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY

Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

(2008) Rihab Nasr et al.   NATURE MEDICINE