Binding of transition metals to S100 proteins

Manganese and Microbial Pathogenesis: Sequestration by the Mammalian Immune System and Utilization by Microorganisms

(2015) Megan Brunjes Brophy et al.   ACS Chemical Biology

The Human Antimicrobial Protein Calgranulin C Participates in Control of Helicobacter pylori Growth and Regulation of Virulence

(2015) Kathryn P. Haley et al.   INFECTION AND IMMUNITY

Nutritional Immunity: S100 Proteins at the Host-Pathogen Interface

(2015) Joseph P. Zackular et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zinc and Manganese Chelation by Neutrophil S100A8/A9 (Calprotectin) Limits ExtracellularAspergillus fumigatusHyphal Growth and Corneal Infection

(2015) Heather L. Clark et al.   JOURNAL OF IMMUNOLOGY

Manganese Binding Properties of Human Calprotectin under Conditions of High and Low Calcium: X-ray Crystallographic and Advanced Electron Paramagnetic Resonance Spectroscopic Analysis

(2015) Derek M. Gagnon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Human calprotectin is an iron-sequestering host-defense protein

(2015) Toshiki G Nakashige et al.   Nature Chemical Biology

Covalent Small Molecule Inhibitors of Ca2+-Bound S100B

(2014) Michael C. Cavalier et al.   BIOCHEMISTRY

Chemotactic Activity of S100A7 (Psoriasin) Is Mediated by the Receptor for Advanced Glycation End Products and Potentiates Inflammation with Highly Homologous but Functionally Distinct S100A15

(2014) R. Wolf et al.   JOURNAL OF IMMUNOLOGY

The Host Protein Calprotectin Modulates the Helicobacter pylori cag Type IV Secretion System via Zinc Sequestration

(2014) Jennifer A. Gaddy et al.   PLoS Pathogens

MntABC and MntH Contribute to Systemic Staphylococcus aureus Infection by Competing with Calprotectin for Nutrient Manganese

(2013) Thomas E. Kehl-Fie et al.   INFECTION AND IMMUNITY

High-Affinity Manganese Coordination by Human Calprotectin Is Calcium-Dependent and Requires the Histidine-Rich Site Formed at the Dimer Interface

(2013) Joshua A. Hayden et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Contributions of the S100A9 C-Terminal Tail to High-Affinity Mn(II) Chelation by the Host-Defense Protein Human Calprotectin

(2013) Megan Brunjes Brophy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens

(2013) S. M. Damo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human S100A3 tetramerization propagates Ca2+/Zn2+ binding states

(2012) Kenji Kizawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Functions of S100 Proteins

(2012) R. Donato et al.   CURRENT MOLECULAR MEDICINE

Calcium Ion Gradients Modulate the Zinc Affinity and Antibacterial Activity of Human Calprotectin

(2012) Megan Brunjes Brophy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural characterization of S100A15 reveals a novel zinc coordination site among S100 proteins and altered surface chemistry with functional implications for receptor binding

(2012) Jill I Murray et al.   BMC STRUCTURAL BIOLOGY

Identification of an Acinetobacter baumannii Zinc Acquisition System that Facilitates Resistance to Calprotectin-mediated Zinc Sequestration

(2012) M. Indriati Hood et al.   PLoS Pathogens

Copper-mediated cross-linking of S100A4, but not of S100A2, results in proinflammatory effects in melanoma cells

(2011) Cathleen Haase-Kohn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nutrient Metal Sequestration by Calprotectin Inhibits Bacterial Superoxide Defense, Enhancing Neutrophil Killing of Staphylococcus aureus

(2011) Thomas E. Kehl-Fie et al.   Cell Host & Microbe

Refined Crystal Structures of Human Ca2+/Zn2+-Binding S100A3 Protein Characterized by Two Disulfide Bridges

(2011) Masaki Unno et al.   JOURNAL OF MOLECULAR BIOLOGY

The role of zinc in the S100 proteins: insights from the X-ray structures

(2010) Olga V. Moroz et al.   AMINO ACIDS

The crystal structures of human S100B in the zinc- and calcium-loaded state at three pH values reveal zinc ligand swapping

(2010) Thorsten Ostendorp et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Phenothiazines inhibit S100A4 function by inducing protein oligomerization

(2010) V. N. Malashkevich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small Molecules Bound to Unique Sites in the Target Protein Binding Cleft of Calcium-Bound S100B As Characterized by Nuclear Magnetic Resonance and X-ray Crystallography

(2009) Thomas H. Charpentier et al.   BIOCHEMISTRY

Identification and Characterization of Binding Sites on S100A7, a Participant in Cancer and Inflammation Pathways

(2009) Rafael León et al.   BIOCHEMISTRY

Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function

(2009) Olga V Moroz et al.   BMC BIOCHEMISTRY

Posttranslational Modifications Affect the Interaction of S100 Proteins with Tumor Suppressor p53

(2009) Jan van Dieck et al.   JOURNAL OF MOLECULAR BIOLOGY

The Crystal Structures of Human S100A12 in Apo Form and in Complex with Zinc: New Insights into S100A12 Oligomerisation

(2009) Olga V. Moroz et al.   JOURNAL OF MOLECULAR BIOLOGY

Divalent Metal Ion Complexes of S100B in the Absence and Presence of Pentamidine

(2008) Thomas H. Charpentier et al.   JOURNAL OF MOLECULAR BIOLOGY

PROMALS3D: a tool for multiple protein sequence and structure alignments

(2008) Jimin Pei et al.   NUCLEIC ACIDS RESEARCH

Metal Chelation and Inhibition of Bacterial Growth in Tissue Abscesses

(2008) Brian D. Corbin et al.   SCIENCE

Calcium, troponin, calmodulin, S100 proteins: From myocardial basics to new therapeutic strategies

(2007) Marcus C. Schaub et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The EF-hand domain: A globally cooperative structural unit

(2002) Melanie R. Nelson et al.   PROTEIN SCIENCE