A Big Bang in spliceosome structural biology

CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast

(2016) Thi Hoang Duong Nguyen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Å resolution

(2016) Thi Hoang Duong Nguyen et al.   NATURE

Molecular architecture of the human U4/U6.U5 tri-snRNP

(2016) D. E. Agafonov et al.   SCIENCE

The 3.8 A structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis

(2016) R. Wan et al.   SCIENCE

Mechanisms and Regulation of Alternative Pre-mRNA Splicing

(2015) Yeon Lee et al.   Annual Review of Biochemistry

Widespread alternative and aberrant splicing revealed by lariat sequencing

(2015) Nicholas Stepankiw et al.   NUCLEIC ACIDS RESEARCH

Structural basis of pre-mRNA splicing

(2015) Jing Hang et al.   SCIENCE

Structure of a yeast spliceosome at 3.6-angstrom resolution

(2015) Chuangye Yan et al.   SCIENCE

The Ribosome Emerges from a Black Box

(2014) V. Ramakrishnan   CELL