Fine-tuning of a radical-based reaction by radical S-adenosyl-L-methionine tryptophan lyase

Substrate-Tuned Catalysis of the RadicalS-Adenosyl-L-Methionine Enzyme NosL Involved in Nosiheptide Biosynthesis

(2015) Xinjian Ji et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tryptophan Lyase (NosL): Mechanistic Insights from Substrate Analogues and Mutagenesis

(2015) Dhananjay M. Bhandari et al.   BIOCHEMISTRY

Biosynthetic Versatility and Coordinated Action of 5′-Deoxyadenosyl Radicals in Deazaflavin Biosynthesis

(2015) Benjamin Philmus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystal Structure of Tryptophan Lyase (NosL): Evidence for Radical Formation at the Amino Group of Tryptophan

(2014) Yvain Nicolet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Radical S-Adenosylmethionine Enzymes

(2014) Joan B. Broderick et al.   CHEMICAL REVIEWS

Reversible H Atom Abstraction Catalyzed by the Radical S-Adenosylmethionine Enzyme HydG

(2014) Benjamin R. Duffus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Radical Intermediate in Tyrosine Scission to the CO and CN- Ligands of FeFe Hydrogenase

(2013) J. M. Kuchenreuther et al.   SCIENCE

Structure-Function Relationships in [FeFe]-Hydrogenase Active Site Maturation

(2012) Yvain Nicolet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biosynthesis of F0, Precursor of the F420 Cofactor, Requires a Unique Two Radical-SAM Domain Enzyme and Tyrosine as Substrate

(2012) Laure Decamps et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Radical-mediated enzymatic carbon chain fragmentation-recombination

(2011) Qi Zhang et al.   Nature Chemical Biology

Nosiheptide Biosynthesis Featuring a Unique Indole Side Ring Formation on the Characteristic Thiopeptide Framework

(2009) Yi Yu et al.   ACS Chemical Biology