Zebrafish models of idiopathic scoliosis link cerebrospinal fluid flow defects to spine curvature

c21orf59/kurly Controls Both Cilia Motility and Polarization

(2016) Kimberly M. Jaffe et al.   Cell Reports

Gpr126/Adgrg6deletion in cartilage models idiopathic scoliosis and pectus excavatum in mice

(2015) Courtney M. Karner et al.   HUMAN MOLECULAR GENETICS

Functional variants of POC5 identified in patients with idiopathic scoliosis

(2015) Shunmoogum A. Patten et al.   JOURNAL OF CLINICAL INVESTIGATION

A PAX1 enhancer locus is associated with susceptibility to idiopathic scoliosis in females

(2015) Swarkar Sharma et al.   Nature Communications

CCDC151 Mutations Cause Primary Ciliary Dyskinesia by Disruption of the Outer Dynein Arm Docking Complex Formation

(2014) Rim Hjeij et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Switching on cilia: transcriptional networks regulating ciliogenesis

(2014) S. P. Choksi et al.   DEVELOPMENT

Kinesin family member 6 (kif6) is necessary for spine development in zebrafish

(2014) Jillian G. Buchan et al.   DEVELOPMENTAL DYNAMICS

ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease

(2014) Madeline Hayes et al.   Nature Communications

Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia

(2013) Christina Austin-Tse et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/ -catenin-dependent cell fate decisions during vertebrate development

(2013) M. Hayes et al.   DEVELOPMENT

Riding the wave of ependymal cilia: Genetic susceptibility to hydrocephalus in primary ciliary dyskinesia

(2013) Lance Lee   JOURNAL OF NEUROSCIENCE RESEARCH

DYX1C1 is required for axonemal dynein assembly and ciliary motility

(2013) Aarti Tarkar et al.   NATURE GENETICS

Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system

(2013) Li-En Jao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt/ -catenin signaling directly regulates Foxj1 expression and ciliogenesis in zebrafish Kupffer's vesicle

(2011) A. Caron et al.   DEVELOPMENT

Top Theories for the Etiopathogenesis of Adolescent Idiopathic Scoliosis

(2011) Wei Jun Wang et al.   JOURNAL OF PEDIATRIC ORTHOPAEDICS

Experimental animal models in scoliosis research: a review of the literature

(2011) Michiel M.A. Janssen et al.   Spine Journal

Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia

(2010) Antonia Borovina et al.   NATURE CELL BIOLOGY

The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation

(2010) Anita Becker-Heck et al.   NATURE GENETICS

The primary cilium: a signalling centre during vertebrate development

(2010) Sarah C. Goetz et al.   NATURE REVIEWS GENETICS

Idiopathic-type scoliosis is not exclusive to bipedalism

(2008) Kristen F. Gorman et al.   MEDICAL HYPOTHESES

Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells

(2008) Tae Joo Park et al.   NATURE GENETICS