Article
Clinical Neurology
Shuochi Wei, Dongmei Wang, Huixia Zhou, Luyao Xia, Yang Tian, Qilong Dai, Rongrong Zhu, Wenjia Wang, Dachun Chen, Meihong Xiu, Li Wang, Xiangyang Zhang
Summary: This study compared the clinical characteristics and cognitive symptoms between heavy smoking and non-heavy smoking groups in Chinese male patients with schizophrenia. The findings showed significant differences between the two groups, with heavy smokers being younger, starting smoking earlier, and having a higher degree of nicotine dependence. Heavy smokers also had lower negative symptom scores and cognitive factor scores.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2022)
Article
Psychiatry
Dimitrios Andreou, Kjetil Nordbo Jorgensen, Stener Nerland, Torill Ueland, Anja Vaskinn, Unn K. Haukvik, Robert H. Yolken, Ole A. Andreassen, Ingrid Agartz
Summary: The results of this cross-sectional study suggest that herpes simplex virus 1 (HSV1) may be associated with brain structural abnormalities and cognitive impairment in patients with severe mental illnesses.
TRANSLATIONAL PSYCHIATRY
(2022)
Review
Psychiatry
Anna Grunze, Sergey Mosolov, Heinz Grunze, Christoph Born
Summary: This narrative review examines the epidemiology, consequences, and treatment options of tobacco use disorder (TUD) and nicotine dependence (ND) in individuals with bipolar disorder (BD). The study found that smoking rates are 2-3 times higher in individuals with BD compared to community samples. Smoking has a detrimental impact on both mental and physical health as well as mortality in individuals with BD. Treatment options include pharmacological interventions and psychosocial interventions.
FRONTIERS IN PSYCHIATRY
(2023)
Review
Behavioral Sciences
Michele Fornaro, Andre F. Carvalho, Michele De Prisco, Anna Maria Mondin, Martina Billeci, Peter Selby, Felice Iasevoli, Michael Berk, David Jonathan Castle, Andrea de Bartolomeis
Summary: The prevalence, correlates, and management of tobacco use disorder (TUD) or nicotine dependence (ND) among people with severe mental illness (SMI) remain unclear. Rates of TUD/ND co-occurrence are high, especially among males, and while bupropion and varenicline show promise for treating schizophrenia patients with TUD/ND, non-pharmacological interventions require further research, especially for those with primary mood disorders. More well-designed RCTs are needed to inform the management of TUD/ND among people with SMI.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Review
Psychiatry
Jesus Garcia-Jimenez, Francisco Jose Gomez-Sierra, Alicia Martinez-Hortelano, Paula Moreno-Merino, Braulio Girela-Serrano, Patricio Molero, Luis Gutierrez-Rojas
Summary: This systematic review examines the association between smoking and suicidal behavior in patients with bipolar disorder (BD). The results show a relationship between smoking and suicidal behavior in BD patients, but due to the heterogeneity of the included articles, a clear relationship could not be established.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychiatry
Bernadette Wendel, Sergi Papiol, Till F. M. Andlauer, Joerg Zimmermann, Jens Wiltfang, Carsten Spitzer, Fanny Senner, Eva C. Schulte, Max Schmauss, Sabrina K. Schaupp, Jonathan Repple, Eva Reininghaus, Jens Reimer, Daniela Reich-Erkelenz, Nils Opel, Susanne Meinert, Carsten Konrad, Farahnaz Kloehn-Saghatolislam, Tilo Kircher, Janos L. Kalman, Georg Juckel, Andreas Jansen, Markus Jaeger, Maria Heilbronner, Martin von Hagen, Katrin Gade, Christian Figge, Andreas J. Fallgatter, Detlef E. Dietrich, Udo Dannlowski, Ashley L. Comes, Monika Budde, Bernhard T. Baune, Volker Arolt, Ion-George Anghelescu, Heike Anderson-Schmidt, Kristina Adorjan, Peter Falkai, Thomas G. Schulze, Heike Bickeboeller, Urs Heilbronner
Summary: The study found that executive functions improved across diagnostic groups and identified nine genome-wide significant SNPs associated with performance change over time. The findings were replicated in a separate study, demonstrating the potential of longitudinally measured phenotypes to reveal novel genetic associations.
TRANSLATIONAL PSYCHIATRY
(2021)
Article
Neurosciences
Alexis E. Whitton, Kathryn E. Lewandowski, Mei-Hua Hall
Summary: The study found that reward learning and sensory gating are correlated in individuals with psychotic disorders, and smoking can influence both processes. Smoking had opposite effects on reward learning and sensory gating in schizophrenia patients compared to psychotic bipolar disorder patients, suggesting nicotine may reveal pathophysiological differences in prediction error circuitry in these distinct psychotic disorders.
Article
Psychology, Clinical
Camilla Barthel Flaaten, Ingrid Melle, Erlend Gardsjord, Thomas Bjella, Magnus Johan Engen, Anja Vaskinn, Gina Asbo, Kristin Fjelnseth Wold, Line Widing, Siv Hege Lyngstad, Beathe Haatveit, Carmen Simonsen, Torill Ueland
Summary: IQ levels in schizophrenia and bipolar disorder patients show changes before and after illness onset, with steeper declines in schizophrenia patients and milder declines in bipolar patients. Over time, all groups showed increases in IQ. However, patients still lag behind healthy controls in terms of IQ levels.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
M. J. Jaen-Moreno, N. Feu, G. I. del Pozo, C. Gomez, L. Carrion, G. M. Chauca, I. Guler, F. J. Montiel, M. D. Sanchez, J. A. Alcala, L. Gutierrez-Rojas, V. Molina, J. Bobes, V. Balanza-Martinez, C. Ruiz-Rull, F. Sarramea
Summary: This study found that one in four outpatients with SMI who smoked had undetected COPD. The Tobacco Intensive Motivational Estimated Risk tool helps with early detection of COPD and maintains its efficacy in smoking cessation.
EUROPEAN PSYCHIATRY
(2021)
Article
Psychology, Multidisciplinary
Barbora Kerkova, Karolina Knizkova, Aneta Sironova, Ales Hruby, Monika Vecerova, Petra Sustova, Juraj Jonas, Mabel Rodriguez
Summary: This study aimed to test the cognitive self-medication hypothesis in individuals with schizophrenia spectrum disorders (SSDs) and found that smokers with SSDs had poorer attentional performance compared to non-smokers, but no significant difference in impulsivity. The extent of cigarette smoking was not associated with attention or impulsivity. These findings suggest that the cognitive self-medication hypothesis in this population needs further testing or reconsideration.
FRONTIERS IN PSYCHOLOGY
(2023)
Review
Substance Abuse
Panagiotis Spanakis, Emily Peckham, Ben Young, Paul Heron, Della Bailey, Simon Gilbody
Summary: This study evaluated the effectiveness of behavioral smoking cessation interventions in adults with severe mental ill health, finding that face-to-face bespoke interventions were more effective compared to usual care.
Article
Psychiatry
Richie Jeremian, Alexandra Malinowski, Zanib Chaudhary, Anil Srivastava, Jessica Qian, Clement Zai, Christopher Adanty, Corinne E. Fischer, Amer M. Burhan, James L. Kennedy, Carol Borlido, Philip Gerretsen, Ariel Graff, Gary Remington, John B. Vincent, John S. Strauss, Vincenzo De Luca
Summary: This study found significant epigenetic age acceleration in individuals with bipolar disorder compared to healthy controls, suggesting potential premature aging phenotype associated with the disease. Further research is needed to explore the precise link between epigenetic age, symptomatology, and disease progression.
PSYCHIATRY RESEARCH
(2022)
Article
Clinical Neurology
James A. Karantonis, Susan L. Rossell, Sean P. Carruthers, Philip Sumner, Matthew Hughes, Melissa J. Green, Christos Pantelis, Katherine E. Burdick, Vanessa Cropley, Tamsyn E. Van Rheenen
Summary: The study found that cross-diagnostic cognitive subgroups of individuals with SSD and BD did not appear to be clearly distinguished by patterns in brain morphology, with only some differences evident in specific brain regions.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychiatry
Nikitas C. Koussis, Bjorn Burgher, Jayson Jeganathan, James G. Scott, Luca Cocchi, Michael Breakspear
Summary: Impairments in emotion expression, experience, and recognition are common in early psychosis. This study investigated the role of the cognitive control system (CCS) in emotional deficits in early psychosis using the affective go/no-go task and computational modeling. Results showed that individuals with early psychosis exhibited higher brain activity in the right posterior insula during inhibitory control of fearful faces. Increased top-down connectivity between regions in the CCS and visual input regions was associated with negative symptoms in the early psychosis cohort. These findings suggest potential targets for remediation of emotional deficits in young persons with early psychosis.
SCHIZOPHRENIA BULLETIN
(2023)
Article
Biochemistry & Molecular Biology
Alena A. Kozlova, Anastasia N. Vaganova, Roman N. Rodionov, Raul R. Gainetdinov, Nadine Bernhardt
Summary: The study aimed to explore the associations between DDAH1, DDAH2, and biological processes implicated in major psychiatric disorders. The results showed no significant differences in the expression levels of DDAH1 and DDAH2 in schizophrenia or bipolar disorder patients compared to controls. However, functional shifts and altered co-expression gene patterns were observed in patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Psychiatry
F. Dickerson, A. Origoni, J. Schroeder, M. Adamos, E. Katsafanas, S. Khushalani, C. L. G. Savage, L. A. B. Schweinfurth, C. Stallings, K. Sweeney, R. Yolken
ACTA PSYCHIATRICA SCANDINAVICA
(2018)
Article
Immunology
Minna Torniainen-Holm, Jaana Suvisaari, Maija Lindgren, Tommi Harkanen, Faith Dickerson, Robert H. Yolken
BRAIN BEHAVIOR AND IMMUNITY
(2018)
Article
Pharmacology & Pharmacy
Deanna L. Kelly, Megan M. Powell, Heidi J. Wehring, MacKenzie A. Sayer, Ann Marie Kearns, Ann L. Hackman, Robert W. Buchanan, Rebecca B. Nichols, Heather A. Adams, Charles M. Richardson, Gopal Vyas, Robert P. McMahon, Amber K. Earl, Kelli M. Sullivan, Fang Liu, Sarah E. Luttrell, Faith B. Dickerson, Stephanie M. Feldman, Supriya Narang, Maju M. Koola, Peter F. Buckley, Jill A. RachBeisel, Joseph P. McEvoy
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
(2018)
Article
Clinical Neurology
Faith Dickerson, Andrea Origoni, Lucy A. B. Schweinfurth, Cassie Stallings, Christina L. G. Savage, Kevin Sweeney, Emily Katsafanas, Holly C. Wilcox, Sunil Khushalani, Robert Yolken
JOURNAL OF NERVOUS AND MENTAL DISEASE
(2018)
Review
Pharmacology & Pharmacy
Emily G. Severance, Faith B. Dickerson, Robert H. Yolken
PHARMACOLOGY & THERAPEUTICS
(2018)
Article
Health Policy & Services
Faith Dickerson, Jennifer Schroeder, Emily Katsafanas, Sunil Khushalani, Andrea E. Origoni, Christina Savage, Lucy Schweinfurth, Catherine R. Stallings, Kevin Sweeney, Robert H. Yolken
PSYCHIATRIC SERVICES
(2018)
Article
Psychiatry
Vishwajit L. Nimgaonkar, Faith Dickerson, Jennie G. Pouget, Kodavali Chowdari, Colm O'Dushlaine, Joel Wood, Lambertus Klei, Bernie Devlin, Robert Yolken
PSYCHIATRY RESEARCH
(2018)
Meeting Abstract
Psychiatry
Faith Dickerson, Robert Yolken
SCHIZOPHRENIA BULLETIN
(2018)
Meeting Abstract
Psychiatry
Alan Breier, Faith Dickerson, Robert Buchanan, Stephen Marder, Keith Neuchterlein, Deepak D'Souza, Michael Francis, Alexander Radnovich, Robert Yolken, Sheldon Preskorn, Matthew Macaluso, Ziyi Yang, Nicole Mehdyoun, Rishi Kakar, Walter Dunn, Debra Hoffmeyer, Gerald Maguire
SCHIZOPHRENIA BULLETIN
(2018)
Meeting Abstract
Psychiatry
Faith Dickerson
SCHIZOPHRENIA BULLETIN
(2018)
Meeting Abstract
Psychiatry
Vishwajit Nimgaonkar, Smita Deshpande, Triptish Bhatia, Konasale Prasad, Faith Dickerson, Raquel Gur, Ruben Gur, Kehui Chen, Joel Wood, Robert H. Yolken
SCHIZOPHRENIA BULLETIN
(2018)
Article
Psychiatry
Jianchun Xiao, Emese Prandovszky, Geetha Kannan, Mikhail V. Pletnikov, Faith Dickerson, Emily G. Severance, Robert H. Yolken
SCHIZOPHRENIA BULLETIN
(2018)
Article
Psychiatry
Triptish Bhatia, Joel Wood, Satish Iyengar, Sreelatha S. Narayanan, Ram Pratap Beniwal, Konasale M. Prasad, Kehui Chen, Robert H. Yolken, Faith Dickerson, Ruben C. Gur, Raquel E. Gur, Smita N. Deshpande, Vishwajit L. Nimgaonkar
SCHIZOPHRENIA RESEARCH
(2018)
Meeting Abstract
Clinical Neurology
M. Frye, B. Coombes, S. McElroy, L. Jones-Brando, M. Veldic, C. Colby, W. Bobo, B. Singh, F. Dickerson, J. Biernacka, R. Yolken
Meeting Abstract
Psychiatry
Faith Dickerson, Robert Yolken
SCHIZOPHRENIA BULLETIN
(2017)