Characterization of a TUTase/RNase complex required forDrosophilagametogenesis

Molecular basis for cytoplasmic RNA surveillance by uridylation‐triggered decay in Drosophila

(2016) Madalena M Reimão‐Pinto et al.   EMBO JOURNAL

TUT‐DIS3L2 is a mammalian surveillance pathway for aberrant structured non‐coding RNAs

(2016) Dmytro Ustianenko et al.   EMBO JOURNAL

Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs

(2016) Anna Łabno et al.   NUCLEIC ACIDS RESEARCH

Identification of factors involved in target RNA-directed microRNA degradation

(2016) Gabrielle Haas et al.   NUCLEIC ACIDS RESEARCH

Uridylation Earmarks mRNAs for Degradation… and More

(2016) Hélène Scheer et al.   TRENDS IN GENETICS

Dis3l2-Mediated Decay Is a Quality Control Pathway for Noncoding RNAs

(2016) Mehdi Pirouz et al.   Cell Reports

Selective Suppression of the Splicing-Mediated MicroRNA Pathway by the Terminal Uridyltransferase Tailor

(2015) Diane Bortolamiol-Becet et al.   MOLECULAR CELL

Uridylation of RNA Hairpins by Tailor Confines the Emergence of MicroRNAs in Drosophila

(2015) Madalena M. Reimão-Pinto et al.   MOLECULAR CELL

Apoptosis Triggers Specific, Rapid, and Global mRNA Decay with 3′ Uridylated Intermediates Degraded by DIS3L2

(2015) Marshall P. Thomas et al.   Cell Reports

Uridylation by TUT4 and TUT7 Marks mRNA for Degradation

(2014) Jaechul Lim et al.   CELL

Deep Sequencing Shows Multiple Oligouridylations Are Required for 3′ to 5′ Degradation of Histone mRNAs on Polyribosomes

(2014) Michael K. Slevin et al.   MOLECULAR CELL

Diversity and dynamics of the Drosophila transcriptome

(2014) James B. Brown et al.   NATURE

Exonuclease hDIS3L2 specifies an exosome-independent 3′-5′ degradation pathway of human cytoplasmic mRNA

(2013) Michal Lubas et al.   EMBO JOURNAL

The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway

(2013) Michal Malecki et al.   EMBO JOURNAL

Highly Improved Gene Targeting by Germline-Specific Cas9 Expression in Drosophila

(2013) Shu Kondo et al.   GENETICS

A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28–let-7 pathway

(2013) Hao-Ming Chang et al.   NATURE

Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs

(2013) D. Ustianenko et al.   RNA

Nuclear RNA surveillance: role of TRAMP in controlling exosome specificity

(2013) Karyn Schmidt et al.   Wiley Interdisciplinary Reviews-RNA

Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility

(2012) Dewi Astuti et al.   NATURE GENETICS

Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7)

(2012) J. E. Thornton et al.   RNA

Zcchc11 Uridylates Mature miRNAs to Enhance Neonatal IGF-1 Expression, Growth, and Survival

(2012) Matthew R. Jones et al.   PLoS Genetics

A Protein Complex Network of Drosophila melanogaster

(2011) K.G. Guruharsha et al.   CELL

From RNA-seq reads to differential expression results

(2011) Alicia Oshlack et al.   GENOME BIOLOGY

MicroRNA Biogenesis via Splicing and Exosome-Mediated Trimming in Drosophila

(2010) Alex S. Flynt et al.   MOLECULAR CELL

Drosophila melanogaster Dis3 N-terminal domains are required for ribonuclease activities, nuclear localization and exosome interactions

(2010) Megan Mamolen et al.   NUCLEIC ACIDS RESEARCH

Target RNA-Directed Trimming and Tailing of Small Silencing RNAs

(2010) S. L. Ameres et al.   SCIENCE

The Many Pathways of RNA Degradation

(2009) Jonathan Houseley et al.   CELL

TUT4 in Concert with Lin28 Suppresses MicroRNA Biogenesis through Pre-MicroRNA Uridylation

(2009) Inha Heo et al.   CELL

Decapping is preceded by 3′ uridylation in a novel pathway of bulk mRNA turnover

(2009) Olivia S Rissland et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells

(2009) John P Hagan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'

(2008) T. E. Mullen et al.   GENES & DEVELOPMENT

The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs

(2008) Katsutomo Okamura et al.   NATURE