Telomerase RNA is more than a DNA template

Human telomerase reverse transcriptase binds to a pre-organized hTRin vivoexposing its template

(2015) Georgeta Zemora et al.   NUCLEIC ACIDS RESEARCH

Telomerase RNA stem terminus element affects template boundary element function, telomere sequence, and shelterin binding

(2015) Christopher J. Webb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Telomere biology: Rationale for diagnostics and therapeutics in cancer

(2015) Philippe Rousseau et al.   RNA Biology

A second essential function of the Est1-binding arm of yeast telomerase RNA

(2015) Kevin J. Lebo et al.   RNA

Structure and function of echinoderm telomerase RNA

(2015) Joshua D. Podlevsky et al.   RNA

Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions

(2015) J. Jiang et al.   SCIENCE

Single-Molecule Fluorescence Resonance Energy Transfer Studies of the Human Telomerase RNA Pseudoknot: Temperature-/Urea-Dependent Folding Kinetics and Thermodynamics

(2014) Erik D. Holmstrom et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Structural basis for protein-RNA recognition in telomerase

(2014) Jing Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Coordinated DNA dynamics during the human telomerase catalytic cycle

(2014) Joseph W. Parks et al.   Nature Communications

Induction of Telomere Dysfunction Mediated by the Telomerase Substrate Precursor 6-Thio-2′-Deoxyguanosine

(2014) Ilgen Mender et al.   Cancer Discovery

The architecture of Tetrahymena telomerase holoenzyme

(2013) Jiansen Jiang et al.   NATURE

A new telomerase RNA element that is critical for telomere elongation

(2013) Nancy Laterreur et al.   NUCLEIC ACIDS RESEARCH

Identification of Telomerase RNAs from Filamentous Fungi Reveals Conservation with Vertebrates and Yeasts

(2013) Paulius V. Kuprys et al.   PLoS One

DNA Repair at Telomeres: Keeping the Ends Intact

(2013) C. J. Webb et al.   Cold Spring Harbor Perspectives in Biology

Schizosaccharomyces pombe Ccq1 and TER1 bind the 14-3-3-like domain of Est1, which promotes and stabilizes telomerase-telomere association

(2012) C. J. Webb et al.   GENES & DEVELOPMENT

Identification of Small Molecule Inhibitors of the HIV-1 Nucleocapsid–Stem-Loop 3 RNA Complex

(2012) Douglas M. Warui et al.   JOURNAL OF MEDICINAL CHEMISTRY

The common ancestral core of vertebrate and fungal telomerase RNAs

(2012) Xiaodong Qi et al.   NUCLEIC ACIDS RESEARCH

Biogenesis of telomerase ribonucleoproteins

(2012) E. D. Egan et al.   RNA

The Molecular Interactions That Stabilize RNA Tertiary Structure: RNA Motifs, Patterns, and Networks

(2011) Samuel E. Butcher et al.   ACCOUNTS OF CHEMICAL RESEARCH

RNA/DNA hybrid binding affinity determines telomerase template-translocation efficiency

(2011) Xiaodong Qi et al.   EMBO JOURNAL

RNA-protein binding interface in the telomerase ribonucleoprotein

(2011) C. J. Bley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Architecture of human telomerase RNA

(2011) Q. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA

(2010) Nak-Kyoon Kim et al.   NUCLEIC ACIDS RESEARCH

Telomerase: An RNP Enzyme Synthesizes DNA

(2010) E. H. Blackburn et al.   Cold Spring Harbor Perspectives in Biology

Investigation of Human Telomerase Holoenzyme Assembly, Activity, and Processivity Using Disease-linked Subunit Variants

(2009) Aaron R. Robart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and comparative analysis of telomerase RNAs from Candida species reveal conservation of functional elements

(2009) S. Gunisova et al.   RNA

Targeting RNA with Small Molecules

(2008) Jason R. Thomas et al.   CHEMICAL REVIEWS

A Flexible Template Boundary Element in the RNA Subunit of Fission Yeast Telomerase

(2008) Jessica A. Box et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stuttering against marginotomy

(2008) Manuel Ares et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Triple-helix structure in telomerase RNA contributes to catalysis

(2008) Feng Qiao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY