☆ 4.0 Article

Parotid Gland Biopsy, the Alternative Way to Diagnose Sjogren Syndrome

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA (2016)

Journal

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Volume 42, Issue 3, Pages 485-+

Publisher

W B SAUNDERS CO-ELSEVIER INC

DOI: 10.1016/j.rdc.2016.03.007

Keywords

Sjogren syndrome; Parotid gland; Labial gland; Salivary gland; Biopsy; Diagnostics

Categories

Rheumatology

Funding

ReumaFonds [13-2-303] Funding Source: researchfish

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Abstract

Salivary gland biopsy is a technique broadly applied for the diagnosis of Sjogren syndrome (SS), lymphoma in SS, and connective tissue disorders (sarcoidosis, amyloidosis). In SS characteristic histology findings are found, including lymphocytic infiltration surrounding the excretory ducts in combination with destruction of acinar tissue. In this article the main techniques are described for taking labial and parotid salivary gland biopsies with respect to their advantages, postoperative complications, and usefulness for diagnostic procedures, monitoring disease progression, and evaluation of treatment.

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