Article
Biochemistry & Molecular Biology
Nathan Favalier, Vincent Veron, Michael Marchand, Anne Surget, Patrick Maunas, Nicolas Turonnet, Stephane Panserat, Lucie Marandel
Summary: The study found that glucose and lipid metabolism in rainbow trout were regulated by nutritional status in all sexes, regardless of carbohydrate intake. Short-term carbohydrate intake at low temperature did not induce specific metabolic changes in broodstock. Additionally, sex differences were demonstrated for the first time regarding the consequences of two days of feeding on glucose and lipid metabolism.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Milena Schonke, Zhixiong Ying, Artemiy Kovynev, Wietse In Het Panhuis, Anne Binnendijk, Sabine van Der Poel, Amanda C. M. Pronk, Trea C. M. Streefland, Menno Hoekstra, Sander Kooijman, Patrick C. N. Rensen
Summary: The timing of exercise training plays a critical role in reducing fat mass and early-stage atherosclerotic lesions, as well as affecting the composition of gut microbiota.
Article
Biochemistry & Molecular Biology
Carmen Tatiana Kalinowski, Monica B. Betancor, Silvia Torrecillas, Matthew Sprague, Laurence Larroquet, Vincent Veron, Stephane Panserat, Maria Soledad Izquierdo, Sadasivam J. Kaushik, Stephanie Fontagne-Dicharry
Summary: This study investigated the influence of dietary astaxanthin (AX) on glucose and lipid metabolism in rainbow trout liver. The results showed that dietary AX had a significant impact on neutral and polar lipids in the liver, hepatocyte size, cytoplasm vacuolization, and gene expression related to TAG turnover, beta-oxidation, PL and cholesterol synthesis. Overall, dietary AX modulates the oxidative phase of the pentose phosphate pathway and the last step of glycolysis, affecting various aspects of lipid metabolism in rainbow trout liver.
Article
Nutrition & Dietetics
Johanna M. S. Lemons, LinShu Liu
Summary: Understanding the impact of diet on gut microbiota and its effect on human health is crucial for future personalized nutrition and healthcare.
Article
Biochemistry & Molecular Biology
Gege Liu, Lixia Chen, Haining Tian, Guoliang Sun, Fulei Wei, Yuqiong Meng, Rui Ma
Summary: The study found that triploid rainbow trout can adapt to different levels of dietary lipids by coordinating metabolism in different tissues. The liver plays a key role in lipid metabolism, with low lipid diets leading to increased lipid transport and glycolysis. Moderate lipid intake enhances lipid uptake and lipogenesis in muscle, while excess lipids are preferentially stored in abdominal adipose tissue through coordinated fatty acid uptake and de novo synthesis.
Article
Multidisciplinary Sciences
Volha Mezhnina, Oghogho P. Ebeigbe, Nikkhil Velingkaar, Allan Poe, Yana Sandlers, Roman V. Kondratov
Summary: The study reveals that caloric restriction and time-restricted feeding can induce rhythmic production of ketone bodies in the blood, which is regulated by PPARα and FGF21 and involves the circadian clock.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Review
Nutrition & Dietetics
Lauren N. Woodie, Kaan T. Oral, Brianna M. Krusen, Mitchell A. Lazar
Summary: Obesity and metabolic diseases are common in industrialized societies due to circadian disruption caused by shift work, jet lag, and social obligations. The circadian rhythm of the hypothalamic suprachiasmatic nucleus (SCN) plays a critical role in regulating physiological, metabolic, and behavioral processes. However, disruptions in external cues or metabolic flexibility can lead to the development of obesity and metabolic disease. This review explores the circadian rhythm of nutrient metabolism and discusses obesity as a circadian disease.
Article
Multidisciplinary Sciences
Paul Petrus, Jacob G. Smith, Kevin B. Koronowski, Siwei Chen, Tomoki Sato, Carolina M. Greco, Thomas Mortimer, Patrick-Simon Welz, Valentina M. Zinna, Kohei Shimaji, Marlene Cervantes, Daniela Punzo, Pierre Baldi, Pura Munoz-Canoves, Paolo Sassone-Corsi, Salvador Aznar Benitah
Summary: Life on Earth relies on molecular clocks and intertissue communication to regulate circadian and metabolic rhythms, with the central clock playing a crucial role in governing metabolic rhythms.
Article
Biochemistry & Molecular Biology
Hanying Xu, Ce Shi, Yangfang Ye, Changbin Song, Changkao Mu, Chunlin Wang
Summary: Artificial night light can disrupt circadian rhythm and lipid metabolism, while time-restricted feeding helps maintain metabolic homeostasis. This study found that continuous light exposure led to lipid accumulation and decreased levels of long-chain polyunsaturated fatty acids in juvenile rainbow trout. However, time-restricted feeding failed to alleviate these negative effects.
Review
Neurosciences
Harry A. Smith, James A. Betts
Summary: Daily rhythms and the timing of meals play a crucial role in coordinating metabolism and health. Experimental manipulation of feeding-fasting cycles can provide insights into the effects of meal timing on metabolism and health.
JOURNAL OF PHYSIOLOGY-LONDON
(2022)
Article
Fisheries
Shuaibo Li, Zhigang Yang, Hongyan Tian, Shengjie Ren, Wuxiao Zhang, Aimin Wang
Summary: Understanding the effects of dietary nutrient ratios on crayfish health and growth can help improve aquaculture production. This study found that an optimal carbohydrate-to-lipid ratio promoted growth performance in red swamp crayfish.
AQUACULTURE REPORTS
(2022)
Article
Biology
Ruth Montero, Justin Tze Ho Chan, Claudia Mueller, Philip Niclas Just, Sven Ostermann, Margareth overland, Kevin Maisey, Tomas Korytar, Bernd Kollner
Summary: This study demonstrates that the immune system and physiological functions of rainbow trout are regulated seasonally, beyond the influence of photoperiod and water temperature. In winter, the fish's immune response is reduced, but the levels of natural antibodies increase.
Article
Nutrition & Dietetics
Lin Yan, Sneha Sundaram, Bret M. Rust, Daniel G. Palmer, LuAnn K. Johnson, Huawei Zeng
Summary: The study hypothesized that consumption of a high-fat diet alters metabolic rhythms in pubertal mice. The results showed that the high-fat diet affected the expression of certain genes related to metabolism in the liver of mice, with the greatest changes occurring during the dark phase. These alterations in metabolic rhythms may disrupt metabolic homeostasis during puberty and contribute to the development of metabolic disorders.
FRONTIERS IN NUTRITION
(2023)
Article
Fisheries
Zhen-Lu Liu, Wei Zhao, Wei-Shan Hu, Bo Zhu, Jia-Jun Xie, Yong-Jian Liu, Li-Xia Tian, Jin Niu
Summary: The study evaluated the effects of dietary lipid levels on lipid metabolism, growth performance, antioxidant ability, and intestinal morphology of rainbow trout under cage culture with flowing water. Results showed that weight gain, growth rate, feed intake, and certain body compositions were influenced by dietary lipid levels. Hepatic SOD activity and mRNA expression of SOD were also affected by dietary lipid levels, indicating a requirement of at least 26.06% lipid for optimal growth and health of rainbow trout in this culture system.
AQUACULTURE REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Kevin P. Kelly, Kate L. J. Ellacott, Heidi Chen, Owen P. McGuinness, Carl Hirschie Johnson
Summary: Time-restricted feeding is crucial for weight management as it affects metabolism, but previous studies have often confused feeding time with fasting time; Researchers have introduced a new time-optimized feeding plan to better analyze the effects of meal timing on the body, and to more accurately simulate human eating patterns in the laboratory; According to the data, controlling the timing of carbohydrate and fat oxidation can effectively limit fat accumulation.
Article
Neurosciences
Adrian Diaz-Rua, Mauro Chivite, Cristina Velasco, Sara Comesana, Jose L. Soengas, Marta Conde-Sieira
Summary: This study evaluated the main components of the cannabinoid system related to feeding conditions in fish. The results suggest a potential role of the endocannabinoid system in the regulation of food intake in fish, but further research is needed.
NUTRITIONAL NEUROSCIENCE
(2022)
Article
Environmental Sciences
Sara Comesana, Floriana Lai, Ann-Elise Olderbakk Jordal, Tiziano Verri, Marit Espe, Jose L. Soengas, Ivar Ronnestad
Summary: The sensing of amino acids in the fish brain, particularly branched-chain amino acids like leucine, plays a role in regulating feed intake through various mechanisms. Studies suggest that members of the SLC family may be involved in the anorectic effect of leucine and serve as an additional amino acid sensing mechanism in fish regulation of feed intake, particularly in brain areas such as the hypothalamus and telencephalon. The different paralogues of amino acid carriers, including LAT1 and SNAT2, showed changes in mRNA abundance in response to varying levels of leucine in the diet in Atlantic salmon.
FRONTIERS IN MARINE SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Nuria Saiz, Lisbeth Herrera-Castillo, Esther Isorna, Maria Jesus Delgado, Marta Conde-Sieira, Jose Luis Soengas, Nuria de Pedro
Summary: This study demonstrates, for the first time in fish, the effects of REV-ERB alpha activation via SR9009, promoting a negative energy balance by reducing energetic inputs and regulating lipid and glucose metabolism.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Physiology
Adrian Diaz-Rua, Mauro Chivite, Sara Comesana, Marta Conde-Sieira, Jose L. Soengas
Summary: We investigated the role of the opioid system in the regulation of food intake in rainbow trout. Our results suggest that the opioid system is not critical for the homeostatic regulation of food intake, but it may play a role in the hedonic regulation.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Plant Sciences
Antia Verde, Jesus M. Miguez, Mercedes Gallardo
Summary: The role of melatonin during the growth and ripening of apple fruit was studied using local varieties. It was found that melatonin stimulates fruit ripening through the induction of ethylene synthesis, and melatonin treatments before ripening improve the final fruit quality.
Article
Fisheries
Ana Basto, Luisa M. P. Valente, Jose L. Soengas, Marta Conde-Sieira
Summary: Understanding the regulation of food intake in fish is crucial for formulating aquafeeds. This study evaluated the short- and mid-term response of European sea bass fed diets with partial and total fishmeal replacement by defatted Tenebrio molitor larvae meal (dTM). The results showed that dTM replacement did not affect food intake regulation in sea bass, but may lead to long-term changes in intermediary metabolism.
Article
Fisheries
Sara Comesana, Mauro Chivite, Ayelen M. Blanco, Maria Alborja-Valado, Jessica Calo, Marta Conde-Sieira, Jose L. Soengas
Summary: This study clarifies the importance of mTOR in the central orexigenic effect of valine in fish. The activation of mTOR is associated with increased feed intake levels, but the precise mechanisms are still unclear.
AQUACULTURE NUTRITION
(2022)
Article
Fisheries
Jessica Calo, Marta Conde-Sieira, Sara Comesana, Jose L. Soengas, Ayelen M. Blanco
Summary: This study demonstrates the presence of a gut-brain axis in fish, as different types and lengths of fatty acids impact feed intake and appetite-regulatory centers in rainbow trout. The findings have important implications for aquaculture due to variations in fatty acid composition in aquafeeds.
Article
Behavioral Sciences
Mauro Chivite, Sara Comesana, Jessica Calo, Jose L. Soengas, Marta Conde-Sieira
Summary: This study demonstrated the presence of a rewarding response mediated by the endocannabinoid system (ECs) in rainbow trout fed a lipid-enriched diet. The agonists of ECs had a bimodal effect on feed intake, and the involvement of specific receptors of ECs in this response was assessed using receptor antagonists.
HORMONES AND BEHAVIOR
(2022)
Article
Fisheries
Jessica Calo, Jose L. Soengas, Jose J. Pastor, Ayelen M. Blanco, Sofia Morais
Summary: This study aimed to investigate the amino acid sensing capacity and hormone production in the gastrointestinal tract (GIT) of rainbow trout in response to proline, fishmeal amino acids, and fishmeal aqueous extract. The results showed that the presence of proline in the GIT led to changes in amino acid sensing systems and hormone production, especially in the proximal regions, accompanied by anorectic response in the hypothalamus. Both the fishmeal aqueous extract and the fishmeal amino acids induced anorectic responses in the hypothalamus, accompanied by increased production of anorectic hormones in the intestine.
Article
Fisheries
F. Lai, S. Comesana, A. S. Gomes, D. Flatejord, I. Tolas, M. Espe, C. De Santis, M. B. Hartviksen, T. Verri, J. L. Soengas, I. Ronnestad
Summary: This study found that high leucine diets reduce feed intake, growth, and hepatosomatic index in Atlantic salmon. It was also found that high leucine diets activate amino acid sensing mechanisms in the brain, which further affects the expression of genes related to appetite control.
Article
Biochemistry & Molecular Biology
Jessica Calo, Sara Comesana, Angel L. Alonso-Gomez, Jose L. Soengas, Ayelen M. Blanco
Summary: This study provides the first evidence of fatty acid sensing mechanisms in the gastrointestinal tract (GIT) of fish and identifies differences in these mechanisms between rainbow trout and mammals.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Nuria Saiz, Cristina Velasco, Nuria de Pedro, Jose Luis Soengas, Esther Isorna
Summary: This study aimed to investigate the potential role of insulin as an intake signal mediating liver entrainment in fish. The experiments showed that the presence of insulin directly increased the abundance of per1a and per2 transcripts in the fish liver. It was found that the involvement of the PI3K/AKT pathway is crucial for insulin-mediated liver entrainment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Alejandra Godino-Gimeno, Per-Ove Thornqvist, Mauro Chivite, Jesus M. Miguez, Svante Winberg, Jose Miguel Cerda-Reverter
Summary: In the past decade, the zebrafish has become an important model organism for studying behavior, neurological disorders, and metabolic diseases. This study used the zebrafish model to investigate how obesity induced by overfeeding affects emotional and cognitive processes. The results showed that obesity impaired short-term memory in zebrafish, but had no effect on anxiety-like behavior.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Agriculture, Dairy & Animal Science
Ana Basto, Luisa M. P. Valente, Vera Sousa, Marta Conde-Sieira, Jose L. Soengas
Summary: This study evaluated the impact of partial and total fishmeal replacement by insect meal on intermediary metabolism of European sea bass. The results showed that the selected insect meal can replace 50% of fishmeal without adversely affecting liver health or intermediary metabolism. However, total fishmeal replacement may compromise fish health in the long-term.
JOURNAL OF ANIMAL SCIENCE
(2023)
