Bile acids induce activation of alveolar epithelial cells and lung fibroblasts through farnesoid X receptor-dependent and independent pathways

Acid and Weakly Acidic Gastroesophageal Reflux and Pepsin Isoforms (A and C) in Tracheal Secretions of Critically Ill Children

(2015) Cristiane Hallal et al.   CHEST

Bile acids stimulate chloride secretion through CFTR and calcium-activated Cl− channels in Calu-3 airway epithelial cells

(2014) Siobhán M. Hendrick et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Gastro-oesophageal reflux and gastric aspiration in idiopathic pulmonary fibrosis patients

(2013) Edoardo Savarino et al.   EUROPEAN RESPIRATORY JOURNAL

Bile acids increase alveolar epithelial permeability via mitogen-activated protein kinase, cytosolic phospholipase A2, cyclooxygenase-2, prostaglandin E2and junctional proteins

(2013) Kang-Cheng Su et al.   RESPIROLOGY

Anti-acid treatment and disease progression in idiopathic pulmonary fibrosis: an analysis of data from three randomised controlled trials

(2013) Joyce S Lee et al.   Lancet Respiratory Medicine

Selective Cox-2 inhibitor celecoxib induces epithelial-mesenchymal transition in human lung cancer cells via activating MEK-ERK signaling

(2012) Z.-l. Wang et al.   CARCINOGENESIS

Glycochenodeoxycholate induces rat alveolar epithelial type II cell death and inhibits surfactant secretion in vitro

(2012) Hu Zhangxue et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gastroesophageal Reflux Therapy Is Associated with Longer Survival in Patients with Idiopathic Pulmonary Fibrosis

(2011) Joyce S. Lee et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

(2011) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Idiopathic Pulmonary Fibrosis: A Disorder of Epithelial Cell Dysfunction

(2011) Donald F. Zoz et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Bile Acids in Sputum and Increased Airway Inflammation in Patients With Cystic Fibrosis

(2011) Ans Pauwels et al.   CHEST

Dose-Response of Five Bile Acids on Serum and Liver Bile Acid Concentrations and Hepatotoxicty in Mice

(2011) Peizhen Song et al.   TOXICOLOGICAL SCIENCES

Does Chronic Microaspiration Cause Idiopathic Pulmonary Fibrosis?

(2010) Joyce S. Lee et al.   AMERICAN JOURNAL OF MEDICINE

Bile Acid Aspiration in Suspected Ventilator-Associated Pneumonia

(2009) Yu-Chung Wu et al.   CHEST

Efficacy of Esomeprazole for Treatment of Poorly Controlled Asthma

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Bile acids repress E-cadherin through the induction of Snail and increase cancer invasiveness in human hepatobiliary carcinoma

(2008) Koji Fukase et al.   CANCER SCIENCE

FXR: a metabolic regulator and cell protector

(2008) Yan-Dong Wang et al.   CELL RESEARCH

Pulmonary Histopathology in an Experimental Model of Chronic Aspiration Is Independent of Acidity

(2008) Tacy E. Downing et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Bile Acid-Induced Lung Injury in Newborn Infants: A Bronchoalveolar Lavage Fluid Study

(2008) E. Zecca et al.   PEDIATRICS