Transforming growth factor (TGF) β1 and Smad signalling pathways: A likely key to EMT-associated COPD pathogenesis

Imprinting of the COPD airway epithelium for dedifferentiation and mesenchymal transition

(2015) Sophie T. Gohy et al.   EUROPEAN RESPIRATORY JOURNAL

TGF-β/Smad signaling through DOCK4 facilitates lung adenocarcinoma metastasis

(2015) Jia-Ray Yu et al.   GENES & DEVELOPMENT

TGF-β-activated SMAD3/4 complex transcriptionally upregulates N-cadherin expression in non-small cell lung cancer

(2015) Haiping Yang et al.   LUNG CANCER

Epithelial mesenchymal transition in smokers: large versus small airways and relation to airflow obstruction

(2015) Malik Mahmood et al.   International Journal of Chronic Obstructive Pulmonary Disease

Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD Risk Locus 19q13.2

(2014) Dorothy M. Ryan et al.   PLoS One

Airway epithelial platelet-activating factor receptor expression is markedly upregulated in chronic obstructive pulmonary disease

(2014) Shakti Shukla et al.   International Journal of Chronic Obstructive Pulmonary Disease

Small Airway Obstruction in COPD

(2013) James C. Hogg et al.   CHEST

Vessel-Associated Transforming Growth Factor-Beta1 (TGF-β1) Is Increased in the Bronchial Reticular Basement Membrane in COPD and Normal Smokers

(2012) Amir Soltani et al.   PLoS One

Common pathogenic mechanisms and pathways in the development of COPD and lung cancer

(2011) Ian A Yang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Angiotensin receptor blockade attenuates cigarette smoke–induced lung injury and rescues lung architecture in mice

(2011) Megan Podowski et al.   JOURNAL OF CLINICAL INVESTIGATION

New insights into the immunology of chronic obstructive pulmonary disease

(2011) Guy G Brusselle et al.   LANCET

Reticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease

(2010) Sukhwinder S. SOHAL et al.   RESPIROLOGY

Regulation of TGF-  signaling by Smad7

(2009) X. Yan et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Meta-analyses on Suspected Chronic Obstructive Pulmonary Disease Genes

(2009) Joanna Smolonska et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

The Pathology of Chronic Obstructive Pulmonary Disease

(2008) James C. Hogg et al.   Annual Review of Pathology-Mechanisms of Disease

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Functional Wnt Signaling Is Increased in Idiopathic Pulmonary Fibrosis

(2008) Melanie Königshoff et al.   PLoS One