Article
Chemistry, Physical
Gunjan P. Deshmukh, Ganapati D. Yadav
Summary: This study explores the use of different polymorphs of MnO2 as catalysts for the selective synthesis of glycerol carbonate through transesterification. The comparison between microwave and conventional heating methods is made, showing advantages in using microwave heating. A kinetic model is developed for the process, enhancing its overall green and sustainable nature.
MOLECULAR CATALYSIS
(2021)
Article
Chemistry, Physical
Marius Chereches, Dana Bejan, Elena Ionela Chereches, Alina Adriana Minea
Summary: The aim of this research is to study the influence of MWCNTs nanoparticles on the thermophysical properties and structure of polyethylene glycol PEG 400. The experimental results show that the samples have good electrical properties, while the viscosity increases with the addition of MWCNTs. The melting and phase transitions were explored, and the relationship between the experimental outcomes and the literature values was discussed.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Physical
Dengfeng Wang, Dong Bai, Jie Xiong, Zheng Chen, Xueying Zhao, Hongwei Wu, Jianfeng Shan, Shuwei Wei, Xuelan Zhang
Summary: A series of Al2O3-ZrO2-nF solid solution catalysts with adjustable acidic-basic properties were fabricated by co-precipitation method. The catalyst with F/Al=1.0 exhibited appropriate acidic-basic property and achieved quantitative and selective transformation of glycerol to glycerol carbonate with a yield of 91.2%. The uniform solid solution structure ensured excellent stability of the catalyst.
APPLIED CATALYSIS A-GENERAL
(2023)
Article
Chemistry, Applied
Araya Chotchuang, Pawitra Kunsuk, Amornpun Phanpitakkul, Sarun Chanklang, Metta Chareonpanich, Anusorn Seubsai
Summary: This study investigated the production of glycerol carbonate using modified sodium aluminate catalysts. The results showed that the catalyst modified with calcium oxide and glycerol as a template produced the most active catalyst. By optimizing the operational parameters, a high yield of glycerol carbonate was achieved.
Article
Chemistry, Physical
Zhihai Zhang, Qinyong Zhang, Jilei Liang, Tingting Ding, Jiaying Wang, Kai Zhu
Summary: A KF/gamma-Al2O3 solid base catalyst was prepared and applied to the synthesis of eugenol ethyl ether (EEE). The effects of different factors on catalyst performance were investigated through measuring the yield of EEE. The results showed that the KF/ gamma-Al2O3 catalyst had good catalytic activity and the optimal conditions were identified.
Article
Biochemistry & Molecular Biology
Mariana Alvarez Serafini, David Gonzalez-Miranda, Gabriela Tonetto, Felix Garcia-Ochoa, Miguel Ladero
Summary: The solventless transcarbonation of glycerol with other organic carbonates driven by alkaline catalysts allows the high yield production of glycerol carbonate, which serves as an advanced humectant and monomer for diverse polycarbonates. The main operational variables affecting the transcarbonation reaction of glycerol and ethylene carbonate catalyzed by zinc stearate were studied, including catalyst concentration, reagent molar ratio, and temperature. A kinetic model was fitted to the experimental data and extended to different temperatures, revealing a bimolecular and elemental reaction mechanism with interfacial behavior.
Article
Green & Sustainable Science & Technology
Shivali Arora, Vijayalakshmi Gosu, U. K. Arun Kumar, Verraboina Subbaramaiah
Summary: The present study investigated the catalytic activity of heterogeneous catalyst for transesterification of glycerol into glycerol carbonate. The study found that lithium impregnated on MCM-41 framework showed better catalytic activity, leading to an increase in the average pore diameter. The optimal conditions for glycerol carbonate yield were determined as 5% Li impregnation, calcination at 450°C, reaction temperature of 90°C for 3 hours, achieving a 93.14% yield.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Chemistry, Physical
Praveen Kumar, Romana Cerc Korosec, Urska Lavrencic Stangar
Summary: A series of Cu-Al hydrotalcite-like compounds were prepared and investigated as catalysts for the transcarbonation of glycerol with dimethyl carbonate. The Cu/Al molar ratio significantly influenced glycerol conversion and glycerol carbonate yield. Among the synthesized catalysts, the Copper-Aluminum (3Cu-Al@500) catalyst exhibited excellent catalytic activity.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Junzheng Shu, Zeyu Wang, Zhifang Zhang, Yichun Ding, Qinlong Zhang, Wenwen Gao, Guilin Liu, Yonglin Yang
Summary: A specific catalyst can efficiently convert phenolic substances in wastewater into ether products, which is beneficial for improving wastewater treatment efficiency and resource utilization.
Article
Energy & Fuels
Rafael Belo Duarte, Marcos Lucio Corazza, Joao Lourenco Castagnari Willimann Pimenta, Luiz Mario de Matos Jorge
Summary: A kinetic study of glycerol hydrodeoxygenation (HDO) on NiMo2C/Al2O3 and Al2O3 catalysts, prepared by sol-gel technique, was conducted at high glycerol concentration (95wt%) in a batch reactor, from 250 degrees C to 285 degrees C. The catalysts' structural and surface properties were characterized, and it was found that impregnation of alumina with Ni and Mo followed by carburization increased crystallite sizes and reduced total acidity. The reactions followed a zeroth order model and had no diffusion limitation. The main products were propanediols, ethylene glycol, long-chain molecules, as well as methane, ethane, and propane.
Review
Energy & Fuels
Najaa Rozulan, Siti Atikah Halim, Nurul Razali, Su Shiung Lam
Summary: Concerns about global warming and energy demand have driven the interest in and action to produce biodiesel as a substitute for fossil fuels. However, the increase in biodiesel production results in the generation of glycerol waste. Utilizing and upgrading this waste can reduce waste volume and increase the market value of glycerol and the sustainability of biodiesel production. This review focuses on the carboxylation of glycerol waste to produce glycerol carbonate (GC) and discusses the impact of catalysts, dehydrating agents, solvents, and other reaction conditions on the conversion and selectivity of glycerol to GC. The use and applications of GC are also reviewed.
BIOMASS CONVERSION AND BIOREFINERY
(2022)
Article
Engineering, Environmental
Shivali Arora, Vijayalakshmi Gosu, Verraboina Subbaramaiah, B. H. Hameed
Summary: In this study, coal fly ash was utilized as a catalytic support for lithium ions by impregnation, with the resulting catalyst's basic properties and catalytic activity towards glycerol conversion being experimentally determined. The maximum catalytic activity was achieved with 2 wt% lithium loaded CFA, calcined at 500 degrees C, leading to a maximum yield of glycerol carbonate. The proposed work has the potential to potentially boost the economy of the biodiesel industry.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Energy & Fuels
Arpita Das, Da Shi, Gopinath Halder, Samuel Lalthazuala Rokhum
Summary: This study investigates the application of Mangifera indica peel calcined ash (MIPCA) as a heterogeneous solid base catalyst for the synthesis of glycerol carbonate (GC) by glycerol transesterification with dimethyl carbonate (DMC) under microwave irradiation. The high basicity, substantial surface area, and mesoporous nature of MIPCA contribute to efficient glycerol conversion. Moreover, the catalyst is readily available, economical, biodegradable, and environmentally friendly as it is derived from biowaste. Under optimal reaction conditions, microwave irradiation achieves high conversion (98.1 +/- 0.6%) and improved selectivity (100%). The catalyst can be reused for up to five consecutive cycles, making it crucial for glycerol to GC transesterification.
Article
Engineering, Environmental
Jialin Yu, Ke Wang, Shibo Shao, Wei Li, Shangfeng Du, Xianfeng Chen, Cong Chao, Xianfeng Fan
Summary: This paper systematically studied the influence of ionic radius, valence state, surface concentration, and basicity of dopants on the catalytic performance of La2O3 in transesterification of glycerol and dimethyl carbonate. It was found that the ionic radius and valence state of the dopants are the determining factors, while the basic site density is not crucial. Among alkali and alkaline earth metals, 25 mol% Na/La2O3 catalyst achieved the highest glycerol conversion (85%) and glycerol carbonate yield (60%). A plausible mechanism of glycerol and dimethyl carbonate transesterification on Na/La2O3 catalyst has been proposed. This research could help understand the promotional role of alkali metals and alkaline earth metals and guide future design of metal oxide catalysts.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Nanoscience & Nanotechnology
Nagendra Kulal, Rajappan Vetrivel, N. S. Ganesh Krishna, Ganapati Shanbhag
Summary: The modification of CeO2 nanorods with divalent transition metal ions enhances oxygen vacancies and improves CO2 activation for glycerol carbonate synthesis. Zn-doped CeO2 nanorods exhibit higher surface reducibility, leading to increased efficiency in the conversion process.
ACS APPLIED NANO MATERIALS
(2021)
Article
Biochemistry & Molecular Biology
Elton L. Borges, Helen A. Goulart, Gelson Perin, Paulo H. Schneider, Guilherme S. Rieder, Pablo A. Nogara, Joao B. T. da Rocha
Summary: This study presents a simple two-step method for the synthesis of arylselanyl hydrazide derivatives, using hypophosphorous acid and polyethylene glycol as a reducing system and hydrazine hydrate as a substrate. The synthesized molecules, structurally similar to isoniazid, showed similar in silico interaction with the lactoperoxidase enzyme as isoniazid. Given the similar in silico interaction of the selenium derivatives of isoniazid, further testing against Mycobacterium tuberculosis is recommended.
CHEMISTRY & BIODIVERSITY
(2022)
Article
Neurosciences
Jaini J. Paltian, Angelica S. Dos Reis, Amanda W. S. Martins, Eduardo B. Blodorn, Eduardo N. Dellagostin, Liane K. Soares, Ricardo F. Schumacher, Vinicius F. Campos, Diego Alves, Cristiane Luchese, Ethel Antunes Wilhelm
Summary: Paclitaxel-induced peripheral neuropathy (PIPN) is a common and complex painful condition associated with paclitaxel (PTX) exposure, leading to decreased quality of life, anxiety, and cognitive impairment. However, there are limited treatment options available. In this study, the therapeutic potential of 4-PSQ was assessed for reversing PIPN and its comorbidities. The results showed that 4-PSQ reduced PTX-induced hypersensitivity, anxiety, and cognitive impairment, possibly through modulation of oxidative stress, neuroinflammation, and calcium homeostasis.
MOLECULAR NEUROBIOLOGY
(2022)
Article
Chemistry, Organic
Ritiele Heck, Thiago Anjos, Maira R. Giehl, Ricardo F. Schumacher, Benhur Godoi
Summary: Flavone and its analogues are important biologically active substances commonly found in diverse plants. This study demonstrates an efficient synthetic strategy for preparing functionalized flavones using catalytic amounts of base and a thiol. The reactions proceed smoothly under transition-metal-free and open to air conditions, yielding the desired compounds in short reaction time.
SYNTHESIS-STUTTGART
(2022)
Article
Chemistry, Organic
Raquel G. Jacob, Daniela Hartwig, Jose Edmilson R. Nascimento, Paola B. Abib, Camila P. Ebersol, Pamela P. P. Nunes, Paloma T. Birmann, Angela M. Casaril, Lucielli Savegnago, Ricardo F. Schumacher
Summary: This study presents a simple and efficient method for the one-pot synthesis of 5-amino-4-(arylselanyl)-1H-pyrazoles catalyzed by CuI/bpy. The obtained compounds showed promising antioxidant effects in various in vitro trials, indicating their potential in protecting against oxidative diseases.
TETRAHEDRON LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Thiago Anjos, Elba L. L. Gutterres, Daniela A. A. Barancelli, Roberta Cargnelutti, Benhur Godoi, Thiago Barcellos, Ricardo F. F. Schumacher
Summary: A synthetic method for organochalcogen-functionalized chromenones has been developed using diorganyl dichalcogenides and alkynyl aryl ketones. Selectfluor(R) mediates the cyclization/organochalcogenation reactions under mild and open-to-air conditions. The versatile methodology allows for the synthesis of organochalcogen-substituted thiochromenone and isocromenone derivatives.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Organic
Helen A. A. Goulart, Daniela R. R. Araujo, Lucas E. B. Iarocz, Bruna R. R. Pizzi, Thiago Barcellos, Marcio S. Silva, Gelson Perin
Summary: We developed a new synthetic method for the production of dialkyl(1-(organolthio)naphthalen-2-yl)phosphates and derivatives. This method involves a dehydrogenative phosphorylation reaction between functionalized naphthols and H-phosphonates, using diphenyl ditelluride as an organocatalyst and sonochemistry as an alternative energy source. The reaction conditions were optimized using factorial design approach, and under ultrasound irradiation, the desired products were obtained in yields ranging from 51-98% after 2 hours of sonication. The protocol also worked well with phenol and thiophenol starting materials.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2023)
Review
Chemistry, Physical
Ricardo H. Bartz, Luiz H. Dapper, Jean C. Kazmierczak, Ricardo F. Schumacher, Gelson Perin, Samuel Thurow, Filipe Penteado, Eder J. Lenardao
Summary: This review provides an overview of recent advances in photocatalyzed reactions for the formation of carbon-sulfur and carbon-selenium bonds. The authors present a comprehensive update on the state of the art in the light-induced synthesis of organochalcogen compounds from 2019 to present, with a total of 136 references and 81 cited articles. The discussion covers topics such as direct sulfenylation of C-C p-bonds to synthesize sulfides, sulfone synthesis, activation of C-sp2-N bond for C-sp2-S bond formation, thiol ester/thioether/thioacetal synthesis, and organoselenium compound synthesis, with detailed reaction conditions and selected examples for each protocol.
Article
Chemistry, Multidisciplinary
Andrei Lucca Belladona, Marina Cardoso Dilelio, Roberta Cargnelutti, Thiago Barcellos, Claudio Cruz Silveira, Ricardo Frederico Schumacher
Summary: A mild and regioselective method for the direct selenylation of 4-(N-substituted-amino)-2H-chromen-2-ones using Selectfluor (R) and diorganyl diselenides has been developed. The reactions were conducted under metal-free conditions at room temperature under air using NaHCO3 as a mild base. This approach provides a wide substrate scope and excellent yields of 3-selenyl-4-(N-substituted-amino)-2H-chromen-2-ones.
Article
Chemistry, Multidisciplinary
Joao M. Anghinoni, Sabrina S. Ferreira, Paulo C. Piquini, Bernardo A. Iglesias, Gelson Perin, Filipe Penteado, Eder J. Lenardao
Summary: This paper describes a new method for synthesizing α-carbonyl selenocyanates by reacting triselenium dicyanide and styrenes under blue light irradiation and O2 atmosphere. The method provides a useful tool for synthesizing α-carbonyl selenocyanates and demonstrates their potential in the synthesis of other compounds. α-Carbonyl selenocyanates were also explored as a synthetic platform for preparing 2-phenylimidazo[1,2-a]pyridine derivatives, which were evaluated for their photophysical properties.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Loana I. Monzon, Nicole C. M. Rocha, Gabriela T. Quadros, Pamela P. P. Nunes, Roberta Cargnelutti, Raquel G. Jacob, Eder J. Lenardao, Gelson Perin, Daniela Hartwig
Summary: A general methodology for synthesizing valuable 4-(phenylchalcogenyl)tetrazolo[1,5-a]quinolines was developed by reacting 2-azidobenzaldehyde with phenylchalcogenylacetonitriles using potassium carbonate as a catalyst. The method tolerated a variety of functional groups and yielded twelve different 4-(phenylchalcogenyl)tetrazolo[1,5-a]quinolines selectively. The structure of the synthesized 4-(phenylselenyl)tetrazolo[1,5-a]quinoline was confirmed by X-ray analysis.
Article
Chemistry, Multidisciplinary
Joao M. Anghinoni, Sabrina S. S. Ferreira, Ricardo F. F. Schumacher, Bernardo A. A. Iglesias, Gelson Perin, Filipe Penteado, Eder J. J. Lenardao
Summary: Benzeneseleninic acid (BSA) derivatives were used as a convenient source of Se(ii)-based electrophiles for the formation of C-Se bonds via thermal decomposition. The reaction with 2-substituted imidazopyridines resulted in the synthesis of 3-selanylimidazopyridines. A total of thirty-four derivatives were prepared, with seventeen of them being previously unreported. The reaction protocol is simple and efficient, yielding only H2O and diaryl diselenide as by-products, which can be easily recovered and reused.
NEW JOURNAL OF CHEMISTRY
(2023)
Review
Chemistry, Multidisciplinary
Paola S. Hellwig, Helen A. Goulart, Laura Abenante, Eder J. Lenardao, Gelson Perin
Summary: Organochalcogen compounds have attracted the attention of research groups due to their powerful chemical and biological activities. Vinyl selenides and tellurides have proven to be important tools in organic synthesis and possess significant biological properties.
RUSSIAN CHEMICAL REVIEWS
(2022)
Article
Chemistry, Organic
Ricardo H. Bartz, Krigor B. Silva, Thiago J. Peglow, Angelita M. Barcellos, Raquel G. Jacob, Eder J. Lenardao, Gelson Perin
Summary: A strategy for the direct synthesis of 3-organylselanylthiochromones and 3-organylselanylchromones via a radical cyclization reaction has been reported in this study. Using Oxone (R) as an oxidizing agent, the method allows for the synthesis of various substituted compounds at good to excellent yields.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
