Article
Biotechnology & Applied Microbiology
Hanyu Chen, Carmen Moraru
Summary: This study explores the potential of using sequential treatments with different wavelengths to enhance the disinfection performance of individual treatments against foodborne pathogens. The results show that pre-treatments with 280 and 222 nm can increase the effectiveness of follow-up 405 nm treatments by inducing higher levels of cellular membrane damage and oxidative stress. These findings provide useful information for light equipment manufacturers, food processors, and healthcare users, and have the potential to improve germicidal light technologies and enhance food safety and public health.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2023)
Article
Oncology
Irena Maliszewska, Waldemar Goldeman
Summary: Antimicrobial photodynamic inactivation using 5-ALA and pentamidine showed significant killing effects on A. baumannii, with a better performance under blue and red laser light in the presence of pentamidine. Pentamidine plays an important role in enhancing the photodynamic inactivation effect.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2021)
Article
Microbiology
Nada T. Felifel, Mahmoud A. Sliem, Zienat Kamel, Joanna Bojarska, Mohamed G. Seadawy, Rehab M. Amin, Sherif M. Elnagdy
Summary: Multidrug-resistant microorganisms pose a significant public health threat, and the use of traditional antibiotics is becoming less effective. Photodynamic therapy (PDT), which utilizes photosensitizers and light to generate Reactive Oxygen Species (ROS) for microorganism killing, shows promise as an alternative. Zinc phthalocyanine (ZnPc) is a potentially suitable photosensitizer due to its antimicrobial properties and ability to be encapsulated in nanoemulsions. In this study, a nanoemulsion was prepared using Miglyol 812N and distilled water, serving as an efficient nanocarrier system for hydrophobic drugs such as ZnPc. The results demonstrated that ZnPc encapsulated in the nanoemulsion significantly reduced cell survival percentages of Staphylococcus aureus and Escherichia coli, highlighting the potential of nanoemulsion-based PDT as an effective alternative for treating multidrug-resistant microorganisms.
Article
Food Science & Technology
Yuchen Zhang, Zhaoyang Ding, Changbo Shao, Jing Xie
Summary: This study evaluated the effect of chlorophyllin-based photodynamic inactivation (Chl-PDI) on biofilm formation and fresh-cut pakchoi quality. The results showed that Chl-PDI reduced biofilm formation, inactivated food spoilage bacteria, and improved the quality of fresh-cut pakchoi. These findings have significant implications for effective processing and traditional vegetable preservation.
Article
Multidisciplinary Sciences
Yuling Xu, Chonglu Li, Shuai Lu, Zhizheng Wang, Shuang Liu, Xiujun Yu, Xiaopeng Li, Yao Sun
Summary: In this study, a Ru(II) metallacycle with long-wavelength emission was rationally designed for deep optical penetration and enhanced chemo-phototherapy activity in vivo. The metallacycle exhibited prominent anticancer capability against various cancer cell lines, especially cisplatin-resistant cells, through inducing cell apoptosis and cell cycle arrest. Precise NIR-II fluorescence imaging guided and long-term monitored chemo-phototherapy was achieved with minimal side effects in A549 tumor model.
NATURE COMMUNICATIONS
(2022)
Article
Chemistry, Applied
Ranulfo Combuca da Silva Junior, Katieli da Silva Souza Campanholi, Fabiana dos Santos Rando, Renato Sonchini Goncalves, Daniele Lazarin-Bidoia, Flavia Amanda Pedroso de Morais, Ana Paula Alves dos Santos Silva, Celso Vataru Nakamura, Magali Soares dos Santos Pozza, Wilker Caetano
Summary: The study aimed to evaluate the photodynamic efficiency of Safranine-O in inactivating Escherichia coli and Staphylococcus aureus, with promising results showing effective inactivation of both bacteria.
Article
Agronomy
Audrey Chua, Leonard Chong, Vinayak Ghate, Hyun-Gyun Yuk, Weibiao Zhou
Summary: This study found that 405 nm LED illumination can effectively inhibit the growth of Botrytis cinerea and Rhizopus stolonifer on tomatoes, while also increasing the antioxidant content of the tomato samples. However, it may lead to a reduction in quality and lycopene content of the tomatoes as well.
POSTHARVEST BIOLOGY AND TECHNOLOGY
(2021)
Article
Oncology
Kamogelo Hlabangwane, Refilwe Matshitse, Muthumuni Managa, Tebello Nyokong
Summary: This research explores the use of photodynamic antimicrobial chemotherapy to develop a new nanomaterial that exhibits good antimicrobial activity against Staphylococcus aureus.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2023)
Article
Multidisciplinary Sciences
Hanyu Chen, Yifan Cheng, Carmen I. Moraru
Summary: This study investigates the antimicrobial effectiveness of 405 nm LEDs against various pathogens and evaluates the impact of different surfaces and packaging materials. The results demonstrate the significant potential of 405 nm LEDs for antimicrobial applications in food processing and healthcare industry.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Applied
Erhan Keyvan, Hatice Ahu Kahraman, Hidayet Tutun, Soner Donmez, Erdi Sen, Zuhal Caliskan, Jerina Rugji, Ahu Demirtas, Ali Ozhan Akyuz
Summary: The antibacterial activity of 405nm LED illumination combined with carvacrol and curcumin against Salmonella Enteritidis and S. Enteritidis PT4 was evaluated at different temperatures and time parameters. The results showed that the combination of LED illumination and carvacrol or curcumin had a stronger antibacterial effect compared to individual treatment. Future studies on adapting the photodynamic inactivation system to control bacteria in various foods may help develop novel strategies to fight against foodborne bacterial pathogens.
FOOD SCIENCE AND TECHNOLOGY INTERNATIONAL
(2023)
Article
Optics
Ye Liu, Yu Liu, Hongling Li, Huidong Xiao, Yingkai Xia, Ruihong Gao, Xiang Li, Quan Zheng
Summary: This article introduces a 405 nm external-cavity semiconductor laser using a volume Bragg grating (VBG) as the feedback element. By adjusting the external cavity length and reducing the wavelength difference, the semiconductor laser achieves stable emission at 405.1 nm. It has a narrow linewidth and good wavelength stability, making it suitable for spectroscopy applications.
Article
Food Science & Technology
Vinayak Ghate, Isabelle Yew (Jia Min), Weibiao Zhou, Hyun-Gyun Yuk
Summary: This study aimed to investigate the influence of temperature and relative humidity on the PDI of fruit spoilage molds and demonstrated its efficacy on fruit surfaces.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2021)
Article
Oncology
Yolande Ikala Openda, Balaji Babu, Tebello Nyokong
Summary: This study discovered that positively charged phthalocyanine complexes can be used for photodynamic therapy and photodynamic antimicrobial chemotherapy, exhibiting stronger inactivation against pathogenic bacteria and higher affinity for biofilm cells. They also showed potential antibacterial and anticancer activity.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2022)
Article
Engineering, Electrical & Electronic
Jose M. Castro, Rick Pimpinella, Bulent Kose, Paul Huang, Asher Novick, Brett Lane
Summary: This study introduces a theoretical model and experiments focusing on estimating and measuring MCDI over multimode optical channels using VCSEL transceivers, evaluating the impact on PAM-4 signals and bit error rate performance at data rates between 100 and 112 Gbps. The analysis highlights potential methods to improve the reach of multimode fiber channels.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Tao Liang, Huanhuan Zhang, Haobo Pan, Ying Zhao
Summary: This research systematically explored the microbiologically induced corrosion (MIC) performance of magnesium in tryptic soy broth with S. aureus or E. coli. The results showed that magnesium in the biotic solution exhibited higher mass loss, thicker degradation product layer, and more severe pitting corrosion compared to the abiotic solution. Electrochemical measurements indicated that the corrosion rate of magnesium in the biotic solution initially increased due to the decrease in pH caused by the consumption of glucose and the accumulation of acidic metabolites, but subsequently decreased due to the reduction of acidic metabolites, production of alkaline compounds, and corrosion protection provided by the corrosion product and biofilm. Furthermore, the corrosion rate of magnesium was higher in high concentrations of S. aureus and E. coli solution during the initial stage but showed a reverse variation later on. Additionally, magnesium exhibited more severe corrosion in S. aureus solution compared to E. coli solution. These findings suggest that the MIC performance of magnesium is closely related to the concentration and species of bacteria.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2022)
Editorial Material
Biochemical Research Methods
Luis M. Oliveira, Igor Meglinski, Valery V. Tuchin
JOURNAL OF BIOPHOTONICS
(2023)
Article
Biochemical Research Methods
Irina N. N. Dolganova, Arsen K. K. Zotov, Larisa P. P. Safonova, Polina V. V. Aleksandrova, Igor V. V. Reshetov, Kirill I. I. Zaytsev, Valery V. V. Tuchin, Vladimir N. N. Kurlov
Summary: This article introduces a sapphire cryoprobe as a potential solution to the problem of tissue freezing monitoring in modern cryosurgery. The probe consists of a sapphire rod manufactured from Al2O3 melt and optical fibers connected to the source and the detector. It enables the detection of tissue optical response for estimating tissue freezing depth. Experimental tests with a gelatin-intralipid tissue phantom demonstrate the feasibility of this concept, with the probe being able to monitor freezing depth up to 10 mm. This highlights the potential of sapphire-based instruments with optical diagnosis in modern cryosurgery.
JOURNAL OF BIOPHOTONICS
(2023)
Article
Spectroscopy
Ana R. Botelho, Hugo F. Silva, Ines S. Martins, Isa C. Carneiro, Sonia D. Carvalho, Rui M. Henrique, Valery V. Tuchin, Luis M. Oliveira
Summary: A fast calculation method was used to obtain the spectral optical properties of human normal and pathological kidney tissues. Both tissues were found to contain melanin and lipofuscin, with the majority of melanin in the pathological kidney converting into lipofuscin.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Editorial Material
Optics
Qingming Luo, Valery V. Tuchin, Lihong Wang
JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES
(2023)
Article
Medicine, General & Internal
Alexey A. Selifonov, Andrey S. Rykhlov, Valery V. Tuchin
Summary: The method of immersion optical clearing can reduce light scattering in tissues, improving the use of optical technologies by clinicians. This study examined the optical and molecular diffusion properties of cat ovarian tissues in the follicular and luteal phases under the influence of glycerol. Results showed that the reflectance and transmittance of the ovaries were significantly lower in the range of 200 to 600 nm compared to longer wavelengths, and the efficiency of optical clearing was lower in the luteal phase. The diffusion coefficient of glycerol/tissue water was estimated, and the time of complete dehydration of ovarian samples was determined.
Article
Engineering, Electrical & Electronic
Jiawei Song, Nan Zeng, Hui Ma, Valery V. Tuchin
Summary: This study proposes a non-invasive polarization optical method to evaluate the microstructural changes in tissues during agent diffusion. The method is validated through experiments using skeletal muscle samples and Monte Carlo simulations. It provides a quantitative characterization of tissue changes and offers insights into the optical clearing stages in tissues.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2023)
Article
Engineering, Electrical & Electronic
Alexey Selifonov, Ekaterina Selifonova, Valery V. V. Tuchin
Summary: The study used diffuse reflectance spectroscopy to investigate the changes in the optical properties of gingival mucosa caused by e-liquids in the range of 200-800 nm. It revealed the presence of three dynamic windows of gingival optical transparency in the ultraviolet (UV) range. The diffusion coefficients of e-liquids with different compositions in the gingival mucosa were estimated, which is of practical importance in disease prevention, pharmaceutical toxicity associated with vaping, and improving the effectiveness of oral UV therapy.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2023)
Article
Engineering, Electrical & Electronic
Maria Rosario Pinheiro, Valery V. V. Tuchin, Luis Manuel Oliveira
Summary: This article explores the use of diffuse reflectance (R-d) spectroscopy to evaluate water and sucrose diffusion properties in skeletal muscle during optical clearing treatments. By treating muscle samples with sucrose-water solutions of different osmolarities, collimated transmittance (T-c) and R-d measurements were performed to obtain diffusion time (t) and diffusion coefficient (D) values. The results show that the estimated t and D values for water in the muscle are 63.1s and 1.72x10(-6) cm(2)/s, while for sucrose they are 261s and 4.86x10(-7) cm(2)/s. Comparing these values with the ones estimated from T-c measurements, the relative differences for t and D are 1.6% and 2.8% for water, and 0.3% and 0.4% for sucrose.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2023)
Article
Biochemical Research Methods
Ali Jaafar, Abbas Albarazanchi, Mohammed Jawad Kadhim, Maxim E. Darvin, Tamas Vaczi, Valery V. Tuchin, Miklos Veres
Summary: The influence of e-liquid on porcine lung immersed in it was investigated using confocal Raman micro-spectroscopy. The results showed that the Raman band intensities related to the lung increased after treatment, except for the surface, which was due to the optical clearing effect caused by alveoli filling with e-liquid. Additionally, oxidative stress and collagen dehydration induced by e-liquid were observed. These findings suggest that nicotine-flavour-free e-liquids could potentially be used as optical clearing agents for enhanced Raman-guided bronchoscopy.
JOURNAL OF BIOPHOTONICS
(2023)
Article
Biochemical Research Methods
Yimeng Wang, Da Huang, Kaiqiang Shu, Yingtong Xu, Yixiang Duan, Qingwen Fan, Qingyu Lin, Valery V. Tuchin
Summary: In this study, an innovative method based on laser-induced breakdown spectroscopy (LIBS) combined with machine learning was developed to distinguish and classify different tumor cell lines. Convolutional neural network (CNN) and support vector machine (SVM) algorithms achieved impressive discrimination performances for tumor cell distinguishing, with an accuracy of 97.72%. The results demonstrate the important role of element heterogeneity in tumor cell distinction and suggest the potential application of LIBS technique for fast classification of tumor cells.
JOURNAL OF BIOPHOTONICS
(2023)
Correction
Biochemistry & Molecular Biology
Roman Verkhovskii, Alexey Ermakov, Oleg Grishin, Mikhail A. Makarkin, Ilya Kozhevnikov, Mikhail Makhortov, Anastasiia Kozlova, Samia Salem, Valery Tuchin, Daniil Bratashov
Article
Medicine, General & Internal
Irina Yu. Yanina, Vadim D. Genin, Elina A. Genina, Dmitry A. Mudrak, Nikita A. Navolokin, Alla B. Bucharskaya, Yury V. Kistenev, Valery V. Tuchin
Summary: This study investigated the effects of e-liquid vaping on the morphological and optical properties of lung tissue. The results showed that e-liquid vaping led to optical clearing of lung tissue and caused emphysematous expansion of the alveoli and thickening of the alveolar septa. Spectral analysis also revealed that the hyperosmotic properties of glycerol and propylene glycol in e-liquids can cause dehydration of lung tissue.
Review
Biochemical Research Methods
Ines S. Martins, Hugo F. Silva, Ekaterina N. Lazareva, Nikita Chernomyrdin, Kirill Zaytsev, Luis M. Oliveira, Valery V. Tuchin
Summary: A critical analysis of methods and results of measurements of the optical properties of tissues in a wide spectral range is presented in this review. The refractive index of biological tissues and liquids is emphasized, as it is crucial for the effective application of optical imaging and diagnostics. The differences in optical parameters between healthy and pathological tissues are discussed, along with the scattering properties of tissues in the terahertz range and the challenges in measuring the optical properties in this range. Additionally, a method for dynamically analyzing the optical properties of tissues under optical clearing is introduced.
BIOMEDICAL OPTICS EXPRESS
(2023)
Article
Biochemical Research Methods
K. V. Berezin, E. V. Grabarchuk, A. M. Lichter, K. N. Dvoretski, V. V. Tuchin
Summary: The results of in vivo immersion optical clearing of human skin under the action of two different optical clearing agents were obtained using optical coherence tomography and molecular modeling methods. The correlations between the efficiency of optical clearing and the energy of intermolecular interaction of the clearing agents with collagen peptide were established.
JOURNAL OF BIOPHOTONICS
(2023)
Article
Physics, Applied
A. S. Kucheryavenko, I. N. Dolganova, A. A. Zhokhov, V. M. Masalov, G. R. Musina, V. V. Tuchin, N. V. Chernomyrdin, A. A. Gavdush, D. R. Il'enkova, S. V. Garnov, K. I. Zaytsev
Summary: In this paper, the researchers studied the use of Terahertz (THz) technology in medical spectroscopy and imaging. They found that tissues can have inhomogeneities at the THz wavelength scale, leading to scattering effects. To address this challenge, they developed a tissue-mimicking phantom and found that the effective optical properties can still be described using the effective medium theory (EMT).
PHYSICAL REVIEW APPLIED
(2023)
