Adenosine A2B receptors play an important role in bone homeostasis

Mesenchymal Stem Cells Ageing: Targeting the “Purinome” to Promote Osteogenic Differentiation and Bone Repair

(2016) J.B. Noronha-Matos et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Biomineralized Matrices Dominate Soluble Cues To Direct Osteogenic Differentiation of Human Mesenchymal Stem Cells through Adenosine Signaling

(2015) Heemin Kang et al.   BIOMACROMOLECULES

Dietary patterns and bone mineral density in Brazilian postmenopausal women with osteoporosis: a cross-sectional study

(2015) N A G de França et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Direct or indirect stimulation of adenosine A2A receptors enhances bone regeneration as well as bone morphogenetic protein-2

(2015) Aránzazu Mediero et al.   FASEB JOURNAL

Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators

(2014) Maria Letizia Trincavelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Long-term Coffee Consumption in Relation to Fracture Risk and Bone Mineral Density in Women

(2013) H. Hallstrom et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Rolofylline, an adenosine A1receptor antagonist, inhibits osteoclast differentiation as an inverse agonist

(2013) Wenjie He et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of adenosine A2Areceptor reduces osteoclast formation via PKA- and ERK1/2-mediated suppression of NFκB nuclear translocation

(2013) Aránzazu Mediero et al.   BRITISH JOURNAL OF PHARMACOLOGY

Adenosine regulates bone metabolism via A1, A2A, and A2B receptors in bone marrow cells from normal humans and patients with multiple myeloma

(2013) Wenjie He et al.   FASEB JOURNAL

Adenosine and bone metabolism

(2013) Aránzazu Mediero et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A2B Adenosine Receptor Promotes Mesenchymal Stem Cell Differentiation to Osteoblasts and Bone Formationin Vivo

(2012) Shannon H. Carroll et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blocking A2B Adenosine Receptor Alleviates Pathogenesis of Experimental Autoimmune Encephalomyelitis via Inhibition of IL-6 Production and Th17 Differentiation

(2012) W. Wei et al.   JOURNAL OF IMMUNOLOGY

Adenosine A1 receptor regulates osteoclast formation by altering TRAF6/TAK1 signaling

(2012) W. He et al.   Purinergic Signalling

Adenosine A2A Receptor Activation Prevents Wear Particle-Induced Osteolysis

(2012) A. Mediero et al.   Science Translational Medicine

Extracellular Purines Promote the Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells to the Osteogenic and Adipogenic Lineages

(2012) Marilena Ciciarello et al.   STEM CELLS AND DEVELOPMENT

Adenosine A2A Receptor Ligation Inhibits Osteoclast Formation

(2011) Aránzazu Mediero et al.   AMERICAN JOURNAL OF PATHOLOGY

CD73-generated adenosine promotes osteoblast differentiation

(2011) Masahide Takedachi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Adenosine A1 receptors (A1Rs) play a critical role in osteoclast formation and function

(2010) Firas M. Kara et al.   FASEB JOURNAL

Role for interleukin-6 in structural joint damage and systemic bone loss in rheumatoid arthritis

(2010) Benoit Le Goff et al.   JOINT BONE SPINE

Cellular and Molecular Mechanisms of Bone Remodeling

(2010) Liza J. Raggatt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY