Differential metformin dose-dependent effects on cognition in rats: role of Akt
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Differential metformin dose-dependent effects on cognition in rats: role of Akt
Authors
Keywords
Cognitive impairment, Metformin, Scopolamine, Akt, Phosphorylated tau, Acetyl cholinesterase activity
Journal
PSYCHOPHARMACOLOGY
Volume 233, Issue 13, Pages 2513-2524
Publisher
Springer Nature
Online
2016-04-25
DOI
10.1007/s00213-016-4301-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Downstream modulation of extrinsic apoptotic pathway in streptozotocin-induced Alzheimer's dementia in rats: Erythropoietin versus curcumin
- (2016) Doaa M. Samy et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The beneficial effects of AMP kinase activation against oxidative stress are associated with prevention of PPARα-cyclophilin D interaction in cardiomyocytes
- (2015) Giselle Barreto-Torres et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Clinical Characteristics for the Relationship between Type-2 Diabetes Mellitus and Cognitive Impairment: A Cross-Sectional Study
- (2015) Yi Zhou et al. Aging and Disease
- Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation
- (2014) Peng-xin Xu et al. BEHAVIOURAL BRAIN RESEARCH
- Metformin protects against seizures, learning and memory impairments and oxidative damage induced by pentylenetetrazole-induced kindling in mice
- (2014) Ran-ran Zhao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inhibitory Effects of Eucommia ulmoides Oliv. Bark on Scopolamine-Induced Learning and Memory Deficits in Mice
- (2014) Seung-Hwan Kwon et al. Biomolecules & Therapeutics
- Type 3 diabetes is sporadic Alzheimer׳s disease: Mini-review
- (2014) Suzanne M. de la Monte EUROPEAN NEUROPSYCHOPHARMACOLOGY
- IFN-γ and TNF-α Are Involved During Alzheimer Disease Progression and Correlate with Nitric Oxide Production: A Study in Algerian Patients
- (2014) Mourad Belkhelfa et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Comparison of the independent and combined effects of sub-chronic therapy with metformin and a stable GLP-1 receptor agonist on cognitive function, hippocampal synaptic plasticity and metabolic control in high-fat fed mice
- (2014) Rachael Lennox et al. NEUROPHARMACOLOGY
- Acute treatment with metformin improves cardiac function following isoproterenol induced myocardial infarction in rats
- (2014) Hamid Soraya et al. Pharmacological Reports
- Metformin Impairs Mitochondrial Function in Skeletal Muscle of Both Lean and Diabetic Rats in a Dose-Dependent Manner
- (2014) Bart Wessels et al. PLoS One
- Decaffeinated coffee prevents scopolamine-induced memory impairment in rats
- (2013) Young Jin Jang et al. BEHAVIOURAL BRAIN RESEARCH
- Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin
- (2013) E. M. Moore et al. DIABETES CARE
- Rivastigmine Alleviates Experimentally Induced Colitis in Mice and Rats by Acting at Central and Peripheral Sites to Modulate Immune Responses
- (2013) Helena Shifrin et al. PLoS One
- A Novel Mechanism of Formaldehyde Neurotoxicity: Inhibition of Hydrogen Sulfide Generation by Promoting Overproduction of Nitric Oxide
- (2013) Xiao-Qing Tang et al. PLoS One
- Metformin: an old but still the best treatment for type 2 diabetes
- (2013) Lilian Beatriz Aguayo Rojas et al. Diabetology & Metabolic Syndrome
- Diabetes drugs and neurological disorders: new views and therapeutic possibilities
- (2013) Cesare Patrone et al. Lancet Diabetes & Endocrinology
- Metformin Activates an Atypical PKC-CBP Pathway to Promote Neurogenesis and Enhance Spatial Memory Formation
- (2012) Jing Wang et al. Cell Stem Cell
- A high-fat-diet-induced cognitive deficit in rats that is not prevented by improving insulin sensitivity with metformin
- (2012) A. D. McNeilly et al. DIABETOLOGIA
- Metformin, Other Antidiabetic Drugs, and Risk of Alzheimer's Disease: A Population-Based Case-Control Study
- (2012) Patrick Imfeld et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Phellodendron amurenseand Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats
- (2012) Bombi Lee et al. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
- Effects of metformin on learning and memory behaviors and brain mitochondrial functions in high fat diet induced insulin resistant rats
- (2012) Hiranya Pintana et al. LIFE SCIENCES
- Aβ Toxicity in Alzheimer's Disease
- (2012) Virve Cavallucci et al. MOLECULAR NEUROBIOLOGY
- Agmatine protects against scopolamine-induced water maze performance impairment and hippocampal ERK and Akt inactivation
- (2012) Maryam Moosavi et al. NEUROPHARMACOLOGY
- Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats
- (2012) Pankaj K. Bagul et al. PHARMACOLOGICAL RESEARCH
- Agmatine, a metabolite of L-arginine, reverses scopolamine-induced learning and memory impairment in rats
- (2012) Tijen Utkan et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice
- (2012) Jiejie Li et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure
- (2011) Claire Thornton et al. BIOCHEMICAL JOURNAL
- Involvement of nitric oxide in granisetron improving effect on scopolamine-induced memory impairment in mice
- (2011) Mehrak Javadi-Paydar et al. BRAIN RESEARCH
- Rehmannia glutinosa Ameliorates Scopolamine-Induced Learning and Memory Impairment in Rats
- (2011) Bombi Lee JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
- Peripheral insulin-sensitizer drug metformin ameliorates neuronal insulin resistance and Alzheimer’s-like changes
- (2011) Amit Gupta et al. NEUROPHARMACOLOGY
- Suppression of nitric oxide synthesis by L-NAME reverses the beneficial effects of pioglitazone on scopolamine-induced memory impairment in mice
- (2010) Nika Allami et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer's type (SDAT)☆
- (2009) Tauheed Ishrat et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Regulation of visceral adipose tissue-derived serine protease inhibitor by nutritional status, metformin, gender and pituitary factors in rat white adipose tissue
- (2009) C. R. González et al. JOURNAL OF PHYSIOLOGY-LONDON
- Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription
- (2009) Y. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cognitive-enhancing and antioxidant activities of iridoid glycosides from Scrophularia buergeriana in scopolamine-treated mice
- (2008) Eun Ju Jeong et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Akt and CHIP coregulate tau degradation through coordinated interactions
- (2008) C. A. Dickey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Methylthioninium chloride reverses cognitive deficits induced by scopolamine: comparison with rivastigmine
- (2008) Serena Deiana et al. PSYCHOPHARMACOLOGY
- Amyloid beta oligomers induce impairment of neuronal insulin receptors
- (2007) Wei-Qin Zhao et al. FASEB JOURNAL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now