Recent Progress on Cu-Catalyzed Asymmetric Conjugate Borylation to alpha,beta-Unsaturated Compounds

Organoborons are an important class of organic compounds, because organoboronic acids and their derivatives can be readily converted into a wide variety of functionalities in a stereospecific manner. Cu-catalyzed asymmetric conjugate borylation of unsaturated compounds with bis(pinacolato)diboron (B(2)pin(2)) has emerged as a novel synthetic tool to afford a variety of organoboron compounds. Herein, this research progress, which involves using bisphosphine, N-heterocyclic carbine, and other chiral ligands, is summarized.