Article
Chemistry, Physical
Shuqi Dong, Jinjin Chen, Kening Qiao, Jian Fang, Yan Yang, Laurent Maron, Bo Liu
Summary: This study focused on using rare-earth metal bisalkyl complexes to catalyze hydroamination reactions and investigated Th, Tb, and Gd-based catalysts for the first time. It was found that in intramolecular hydroamination, an increase in metal ion radius led to a linear increase in rate, while the reactivity pattern in intermolecular hydroamination showed the opposite trend with respect to ionic radius size.
Article
Chemistry, Multidisciplinary
Showkat Ahmad Bhat, Qazi Naveed Ahmed, Khursheed Ahmad Bhat
Summary: An efficient strategy for the stereoselective amidation of alkynes has been reported. This method is characterized by its operational simplicity, excellent tolerance of functional groups, broad substrate scope, and fast kinetics to produce Z-enamides. Additionally, this method has been successfully used for the facile synthesis of natural products such as lansiumamide A, lansiumamide B, and Z-alatamide. Notably, DMSO plays a crucial dual role as both a hydrogen source and solvent.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Applied
Xin-Hua Peng, Rui Bai, Shanshan Liu, Zhuo Li, Lin-Yu Jiao
Summary: A novel and efficient protocol for the rare-earth metal salt-catalyzed substitution of phosphoryl azides with amines was disclosed. The methodology generated a series of phosphoryl amides, but secondary analogues or anilines were reluctant to undergo desired transformations.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Shona Banjo, Keisuke Nakata, Eiko Nakasuji, Soichiro Yasui, Noritaka Chida, Takaaki Sato
Summary: This study reports a copper-catalyzed electrophilic enamidation starting from alkynes. Hydrozirconation of an alkyne with the Schwartz reagent forms a vinyl zirconium intermediate, which undergoes a copper-catalyzed electrophilic enamidation with dioxazolones. The high functional group tolerance of hydrozirconation enables the use of functionalized alkynes, including esters. The developed conditions are successfully applied to synthesize partial structures found in biologically active natural products.
Article
Multidisciplinary Sciences
Yao Zhang, Deyong Qiao, Mei Duan, You Wang, Shaolin Zhu
Summary: In this study, a new synthetic method was reported for the highly enantioselective synthesis of chiral alpha-aminoboronates and their derivatives under mild conditions. The method was demonstrated to be efficient for the synthesis of a current pharmaceutical agent.
NATURE COMMUNICATIONS
(2022)
Article
Chemistry, Inorganic & Nuclear
Nadia Ismaeel, Zhixing Zhuo, Sajid Imran, Dan Yuan, Yingming Yao
Summary: Rare earth/lithium complexes stabilized by ethylenediamine-bridged bis(phenolate) ligands have been synthesized and characterized. Among them, the yttrium/lithium complex showed high catalytic activity for the amidation of primary aliphatic amines.
DALTON TRANSACTIONS
(2022)
Article
Biochemistry & Molecular Biology
Annemiek van Zadelhoff, Jean-Paul Vincken, Wouter J. C. de Bruijn
Summary: Phenol amides are bioactive compounds found naturally in plants, known for their antioxidant, anti-inflammatory, and anticancer activities. However, purification from plants is difficult and existing syntheses are complex and limited. In this study, a simple and efficient one-pot synthesis of phenol amides was developed, allowing for the synthesis of diverse compounds with different subunits. This method provides a valuable tool for further studies on phenol amides.
Article
Chemistry, Multidisciplinary
William I. Nicholson, Fabien Barreteau, Jamie A. Leitch, Riley Payne, Ian Priestley, Edouard Godineau, Claudio Battilocchio, Duncan L. Browne
Summary: The direct mechanochemical amidation of esters by ball milling is a simple and efficient method for preparing a diverse library of amide structures. This method is specifically effective for heteroaromatic and heterocyclic components. It has been successfully applied to the synthesis of active pharmaceutical ingredients and agrochemicals, as well as gram-scale synthesis of active pharmaceuticals without the need for a reaction solvent.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Organic
Joydev K. K. Laha, Anjali Gupta, Upma Gulati, Mandeep Kaur Hunjan, J. Patrick Weber, Martin Breugst
Summary: This study explores the application of isoniazid and other pyridine acyl radicals in organic synthesis. The radicals are generated through denitrogenation reactions and react with amines to yield pyridine carboxamides in moderate to high yields. The method offers mild and metal-free reaction conditions, water as a solvent, a wide substrate scope, and excellent functional-group tolerance.
ORGANIC CHEMISTRY FRONTIERS
(2022)
Article
Chemistry, Inorganic & Nuclear
Yuyuan Xiao, Rong Sun, Jiefeng Liang, Yuhui Fang, Zheng Liu, Shangda Jiang, Bingwu Wang, Song Gao, Wenliang Huang
Summary: The synthesized rare earth metal complexes exhibit complex electronic structures and magnetic behaviors. The structural and magnetic data are consistent with density functional theory calculations, revealing the antiferromagnetic coupling between the radical anions.
INORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Organic
Michael Hitt, Andrew Norris, Andrei N. N. Vedernikov
Summary: A series of N-aroyloxyquinuclidinium salts were synthesized and used as reagents for efficient three-component Ritter-Mumm-type oxidative C-H imidation reactions. The benzylic C-H bonds of 1 & DEG; and 2 & DEG; substituents were used as limiting reagents, with nitriles as the source of imide nitrogen under photocatalytic conditions. These reagents also showed slightly lower reactivity towards cycloalkanes.
Article
Chemistry, Organic
Sumi Changmai, Tribeni Gogoi, Jyotshna Phukon, Bipul Das, Sanjib Gogoi
Summary: This article describes the first use of sulfoxonium ylides for the synthesis of alpha-ketoamides via a Ru(ii)-catalyzed amidation reaction with amines. Interestingly, when sulfoxonium ylides were reacted with 2-phenylindoles using the same Ru(ii)-catalyzed reaction, indolo[2,1-a]isoquinolines were obtained instead of alpha-ketoamides.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Metallurgy & Metallurgical Engineering
Vladimir Rychkov, Vladimir Baulin, Evgeny Kirillov, Sergey Kirillov, Grigory Bunkov, Denis Smyshlyaev, Maxim Botalov, Vladimir Semenishchev, Andrey Malyshev, Aslanbek Taukin, Alina Yuldashbaeva, Egor Gaidashov
Summary: A series of extraction chromatographic resins containing various phosphorus-containing and DGA-based extractants and ionic liquids were synthesized and studied for their sorption characteristics for rare earth elements (REE) in sulfate solutions. The study found that the resin capacity for REE in sulfuric acid solutions was not affected by the matrix type, and the acidity of the aqueous phase played a significant role in lanthanides sorption from sulfate solutions.
Article
Polymer Science
Fen You, Xiaoyu Wang, Wenyu Shi, Xuyang Yan, Xiaochao Shi
Summary: This study successfully synthesized polymers with diverse polar functionalities, including highly regular polymers and copolymers, using a rare-earth metal catalytic system. The composition of the copolymers could be easily controlled by the initial comonomer feed ratio.
Article
Engineering, Environmental
Pengcheng Li, Long Chen, Zuxin Wen, Daxu Zhang, Ying Zhang, Ning Zhang, Gen Chen, Xiaohe Liu
Summary: In this study, rare earth metal salts were used as electrolyte additives to optimize the solvation structure of lithium ions and improve the performance of lithium metal anode. The resulting interphase from electrochemical reactions facilitated stable and efficient Li deposition, leading to enhanced safety and cycling stability of lithium metal batteries. This strategy provides a promising approach for the design and optimization of electrolytes for next-generation high-capacity lithium batteries.
CHEMICAL ENGINEERING JOURNAL
(2022)
