Journal
PROTEOMICS
Volume 16, Issue 11-12, Pages 1607-1612Publisher
WILEY
DOI: 10.1002/pmic.201600133
Keywords
Image fusion; Molecular analysis; Technology; Tissue imaging mass spectrometry
Funding
- NIH [P 41 GM 103391]
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Imagingmass spectrometry provides a powerful tool formonitoring and discovery ofmolecular processes in the spatial domain in tissues for research and practical applications in both biology and medicine. This technology directly measures molecular compounds in tissues without the use of target-specific reagents such as antibodies, is applicable to a wide variety of analytes, and can provide spatial resolutions below the single cell level. Importantly, it has paradigm shifting capabilities in clinical applications, especially for anatomic pathology.
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