Conserved 33-kb haplotype in the MHC class III region regulates chronic arthritis

Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat

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Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases

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The genetics of human autoimmune disease: A perspective on progress in the field and future directions

(2015) Michael F. Seldin   JOURNAL OF AUTOIMMUNITY

Immunogenetics of rheumatoid arthritis: Understanding functional implications

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Positional Identification ofRT1-B(HLA-DQ) as Susceptibility Locus for Autoimmune Arthritis

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Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies

(2015) Judy H Cho et al.   NATURE MEDICINE

Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity

(2014) Buhm Han et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Etanercept: A Review of Its Use in Autoimmune Inflammatory Diseases

(2014) Lesley J. Scott   DRUGS

Lymphotoxin-LIGHT Pathway Regulates the Interferon Signature in Rheumatoid Arthritis

(2014) Jadwiga Bienkowska et al.   PLoS One

Natural Polymorphisms in Tap2 Influence Negative Selection and CD4∶CD8 Lineage Commitment in the Rat

(2014) Jonatan Tuncel et al.   PLoS Genetics

Genome Sequencing Reveals Loci under Artificial Selection that Underlie Disease Phenotypes in the Laboratory Rat

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Etanercept in the treatment of rheumatoid arthritis

(2013) Laura Hunt et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Population-specific recombination sites within the human MHC region

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Genetics of rheumatoid arthritis contributes to biology and drug discovery

(2013) Yukinori Okada et al.   NATURE

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats

(2013) Amelie Baud et al.   NATURE GENETICS

Class II major histocompatibility complex-associated response to type XI collagen regulates the development of chronic arthritis in rats

(2012) Jonatan Tuncel et al.   ARTHRITIS AND RHEUMATISM

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

(2012) Soumya Raychaudhuri et al.   NATURE GENETICS

Predicting the Functional Effect of Amino Acid Substitutions and Indels

(2012) Yongwook Choi et al.   PLoS One

Meta-analysis identified the TNFA -308G > A promoter polymorphism as a risk factor for disease severity in patients with rheumatoid arthritis

(2012) Erik JM Toonen et al.   ARTHRITIS RESEARCH & THERAPY

The balance of expression of PTPN22 splice forms is significantly different in rheumatoid arthritis patients compared with controls

(2012) Marcus Ronninger et al.   Genome Medicine

The Long Path from QTL to Gene

(2012) Norman R. Drinkwater et al.   PLoS Genetics

Integrating Autoimmune Risk Loci with Gene-Expression Data Identifies Specific Pathogenic Immune Cell Subsets

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Pervasive haplotypic variation in the spliceo-transcriptome of the human major histocompatibility complex

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Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

(2011) Nicolas F Delahaye et al.   NATURE MEDICINE

Multiple common variants for celiac disease influencing immune gene expression

(2010) Patrick C A Dubois et al.   NATURE GENETICS

Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci

(2009) Charlotte Vignal et al.   ARTHRITIS AND RHEUMATISM

Mapping complex disease traits with global gene expression

(2009) William Cookson et al.   NATURE REVIEWS GENETICS

Progress and prospects in rat genetics: a community view

(2008) Timothy J Aitman et al.   NATURE GENETICS

Positional cloning of the Igl genes controlling rheumatoid factor production and allergic bronchitis in rats

(2008) C. Rintisch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High levels of Lymphotoxin-Beta (LT-Beta) gene expression in rheumatoid arthritis synovium: clinical and cytokine correlations

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