Comprehensive structural and dynamical view of an unfolded protein from the combination of single-molecule FRET, NMR, and SAXS

Single-Molecule FRET Spectroscopy and the Polymer Physics of Unfolded and Intrinsically Disordered Proteins

(2016) Benjamin Schuler et al.   Annual Review of Biophysics

Probing the Action of Chemical Denaturant on an Intrinsically Disordered Protein by Simulation and Experiment

(2016) Wenwei Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative Assessments of the Distinct Contributions of Polypeptide Backbone Amides versus Side Chain Groups to Chain Expansion via Chemical Denaturation

(2015) Alex S. Holehouse et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-molecule spectroscopy of protein conformational dynamics in live eukaryotic cells

(2015) Iwo König et al.   NATURE METHODS

Progress in studying intrinsically disordered proteins with atomistic simulations

(2015) Nathaniel Stanley et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Exploring Free-Energy Landscapes of Intrinsically Disordered Proteins at Atomic Resolution Using NMR Spectroscopy

(2014) Malene Ringkjøbing Jensen et al.   CHEMICAL REVIEWS

Single-Molecule Studies of Intrinsically Disordered Proteins

(2014) Marco Brucale et al.   CHEMICAL REVIEWS

Introducing Protein Intrinsic Disorder

(2014) Johnny Habchi et al.   CHEMICAL REVIEWS

Long-Range Correlated Dynamics in Intrinsically Disordered Proteins

(2014) Giacomo Parigi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Concerted Dihedral Rotations Give Rise to Internal Friction in Unfolded Proteins

(2014) Ignacia Echeverria et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Temperature-dependent solvation modulates the dimensions of disordered proteins

(2014) R. Wuttke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular origins of internal friction effects on protein-folding rates

(2014) David de Sancho et al.   Nature Communications

Combining Experiments and Simulations Using the Maximum Entropy Principle

(2014) Wouter Boomsma et al.   PLoS Computational Biology

Single-molecule spectroscopy of protein folding dynamics—expanding scope and timescales

(2013) Benjamin Schuler et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Single-molecule spectroscopy of the unexpected collapse of an unfolded protein at low pH

(2013) Hagen Hofmann et al.   JOURNAL OF CHEMICAL PHYSICS

Exploring the role of internal friction in the dynamics of unfolded proteins using simple polymer models

(2013) Ryan R. Cheng et al.   JOURNAL OF CHEMICAL PHYSICS

Single-Molecule Spectroscopy of Cold Denaturation and the Temperature-Induced Collapse of Unfolded Proteins

(2013) Mikayel Aznauryan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recovering a Representative Conformational Ensemble from Underdetermined Macromolecular Structural Data

(2013) Konstantin Berlin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Conformational Ensembles of α-Synuclein and Tau: Combining Single-Molecule FRET and Simulations

(2012) Abhinav Nath et al.   BIOPHYSICAL JOURNAL

Small-Angle X-ray Scattering and Single-Molecule FRET Spectroscopy Produce Highly Divergent Views of the Low-Denaturant Unfolded State

(2012) Tae Yeon Yoo et al.   JOURNAL OF MOLECULAR BIOLOGY

Sequence-Specific Mapping of the Interaction between Urea and Unfolded Ubiquitin from Ensemble Analysis of NMR and Small Angle Scattering Data

(2012) Jie-rong Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Peptide Chain Dynamics in Light and Heavy Water: Zooming in on Internal Friction

(2012) Julius C. F. Schulz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantifying internal friction in unfolded and intrinsically disordered proteins with single-molecule spectroscopy

(2012) A. Soranno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polymer scaling laws of unfolded and intrinsically disordered proteins quantified with single-molecule spectroscopy

(2012) H. Hofmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy

(2012) Alessandro Borgia et al.   Nature Communications

How, when and why proteins collapse: the relation to folding

(2011) Gilad Haran   CURRENT OPINION IN STRUCTURAL BIOLOGY

Effect of Urea on the β-Hairpin Conformational Ensemble and Protein Denaturation Mechanism

(2011) Anna Berteotti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural analysis of intrinsically disordered proteins by small-angle X-ray scattering

(2011) Pau Bernadó et al.   Molecular BioSystems

Side-Chain χ1Conformations in Urea-Denatured Ubiquitin and Protein G from3JCoupling Constants and Residual Dipolar Couplings

(2010) Navratna Vajpai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Charge interactions can dominate the dimensions of intrinsically disordered proteins

(2010) S. Muller-Spath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improving the quality of NMR and crystallographic protein structures by means of a conformational database potential derived from structure databases

(2010) John Kuszewski et al.   PROTEIN SCIENCE

Protein dynamics from single-molecule fluorescence intensity correlation functions

(2009) Irina V. Gopich et al.   JOURNAL OF CHEMICAL PHYSICS

Quantitative Description of Backbone Conformational Sampling of Unfolded Proteins at Amino Acid Resolution from NMR Residual Dipolar Couplings

(2009) Gabrielle Nodet et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative Modelfree Analysis of Urea Binding to Unfolded Ubiquitin Using a Combination of Small Angle X-ray and Neutron Scattering

(2009) Frank Gabel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DOTA-M8: An Extremely Rigid, High-Affinity Lanthanide Chelating Tag for PCS NMR Spectroscopy

(2009) Daniel Häussinger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ensemble Calculations of Unstructured Proteins Constrained by RDC and PRE Data: A Case Study of Urea-Denatured Ubiquitin

(2009) Jie-rong Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interplay of  -synuclein binding and conformational switching probed by single-molecule fluorescence

(2009) A. C. M. Ferreon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-molecule spectroscopy of the temperature-induced collapse of unfolded proteins

(2009) D. Nettels et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational distributions of unfolded polypeptides from novel NMR techniques

(2008) Sebastian Meier et al.   JOURNAL OF CHEMICAL PHYSICS

Unfolded Protein and Peptide Dynamics Investigated with Single-Molecule FRET and Correlation Spectroscopy from Picoseconds to Seconds†

(2008) Daniel Nettels et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Collapse transition in proteins

(2008) Guy Ziv et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Urea denaturation by stronger dispersion interactions with proteins than water implies a 2-stage unfolding

(2008) L. Hua et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA