Distinct cortical and striatal actions of a β-arrestin–biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties

Function and developmental origin of a mesocortical inhibitory circuit

(2015) Anna Kabanova et al.   NATURE NEUROSCIENCE

Gamma Rhythms Link Prefrontal Interneuron Dysfunction with Cognitive Inflexibility in Dlx5/6+/− Mice

(2015) Kathleen K.A. Cho et al.   NEURON

Transgenic Mice for Intersectional Targeting of Neural Sensors and Effectors with High Specificity and Performance

(2015) Linda Madisen et al.   NEURON

Effects of β-Arrestin-Biased Dopamine D2 Receptor Ligands on Schizophrenia-Like Behavior in Hypoglutamatergic Mice

(2015) Su M Park et al.   NEUROPSYCHOPHARMACOLOGY

Deficits in Prefrontal Cortical and Extrastriatal Dopamine Release in Schizophrenia

(2015) Mark Slifstein et al.   JAMA Psychiatry

Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity

(2015) Sean M. Peterson et al.   PLoS One

The Novel Object Recognition Test in Rodents in Relation to Cognitive Impairment in Schizophrenia

(2014) Lakshmi Rajagopal et al.   CURRENT PHARMACEUTICAL DESIGN

Cell type–specific mRNA purification by translating ribosome affinity purification (TRAP)

(2014) Myriam Heiman et al.   Nature Protocols

Obsessive–compulsive disorder: an integrative genetic and neurobiological perspective

(2014) David L. Pauls et al.   NATURE REVIEWS NEUROSCIENCE

Clozapine Acts as an Agonist at Serotonin 2A Receptors to Counter MK-801-Induced Behaviors through a βArrestin2-Independent Activation of Akt

(2014) Cullen L Schmid et al.   NEUROPSYCHOPHARMACOLOGY

Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia

(2014) M. Heiman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure–Functional Selectivity Relationship Studies of β-Arrestin-Biased Dopamine D2 Receptor Agonists

(2012) Xin Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dual Control of Dopamine Synthesis and Release by Presynaptic and Postsynaptic Dopamine D2 Receptors

(2012) A. Anzalone et al.   JOURNAL OF NEUROSCIENCE

Hippocampal volume and total cell numbers in major depressive disorder

(2012) Justin A. Cobb et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Quantitative Analysis of Focused A-To-I RNA Editing Sites by Ultra-High-Throughput Sequencing in Psychiatric Disorders

(2012) Hu Zhu et al.   PLoS One

Deletion of GSK3  in D2R-expressing neurons reveals distinct roles for  -arrestin signaling in antipsychotic and lithium action

(2012) N. M. Urs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strategies to Discover Unexpected Targets for Drugs Active at G Protein–Coupled Receptors

(2011) John A. Allen et al.   Annual Review of Pharmacology and Toxicology

Melanocortin-4 Receptors Expressed by Cholinergic Neurons Regulate Energy Balance and Glucose Homeostasis

(2011) Jari Rossi et al.   Cell Metabolism

GABAergic interneuron origin of schizophrenia pathophysiology

(2011) Kazu Nakazawa et al.   NEUROPHARMACOLOGY

Discovery of  -Arrestin-Biased Dopamine D2 Ligands for Probing Signal Transduction Pathways Essential for Antipsychotic Efficacy

(2011) J. A. Allen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia

(2011) David A. Lewis et al.   TRENDS IN NEUROSCIENCES

Expression of Interneuron Markers in the Dorsolateral Prefrontal Cortex of the Developing Human and in Schizophrenia

(2010) Samantha J. Fung et al.   AMERICAN JOURNAL OF PSYCHIATRY

A Dopamine D1 Receptor-Dependent β-Arrestin Signaling Complex Potentially Regulates Morphine-Induced Psychomotor Activation but not Reward in Mice

(2010) Nikhil M Urs et al.   NEUROPSYCHOPHARMACOLOGY

A kinesin signaling complex mediates the ability of GSK-3  to affect mood-associated behaviors

(2010) J. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors

(2010) H. S. Bateup et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physiology and Pharmacology of Striatal Neurons

(2009) Anatol C. Kreitzer   Annual Review of Neuroscience

Getting specialized: presynaptic and postsynaptic dopamine D2 receptors

(2009) Claudia De Mei et al.   CURRENT OPINION IN PHARMACOLOGY

β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice

(2009) Robert W. Walters et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of Glycogen Synthase Kinase-3  Is Required for Hyperdopamine and D2 Receptor-Mediated Inhibition of Synaptic NMDA Receptor Function in the Rat Prefrontal Cortex

(2009) Y.-C. Li et al.   JOURNAL OF NEUROSCIENCE

In Vitro and in Vivo Evidence for a Lack of Interaction with Dopamine D2 Receptors by the Metabotropic Glutamate 2/3 Receptor Agonists 1S,2S,5R,6S-2-Aminobicyclo[3.1.0]hexane-2,6-bicaroxylate Monohydrate (LY354740) and (-)-2-Oxa-4-aminobicyclo[3.1.0] Hexane-4,6-dicarboxylic Acid (LY379268)

(2009) M. J. Fell et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Decreased glutamic acid decarboxylase67 mRNA expression in multiple brain areas of patients with schizophrenia and mood disorders

(2009) Mia Thompson et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

(2009) Vikaas S. Sohal et al.   NATURE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

The Dopamine Hypothesis of Schizophrenia: Version III--The Final Common Pathway

(2009) O. D. Howes et al.   SCHIZOPHRENIA BULLETIN

Conserved Regional Patterns of GABA-Related Transcript Expression in the Neocortex of Subjects With Schizophrenia

(2008) Takanori Hashimoto et al.   AMERICAN JOURNAL OF PSYCHIATRY

A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior

(2008) Jean-Martin Beaulieu et al.   CELL

Quantitative Analysis of the Expression of Dopamine D1 and D2 Receptors in Pyramidal and GABAergic Neurons of the Rat Prefrontal Cortex

(2008) N. Santana et al.   CEREBRAL CORTEX

A Neonatal Ventral Hippocampal Lesion Causes Functional Deficits in Adult Prefrontal Cortical Interneurons

(2008) K. Y. Tseng et al.   JOURNAL OF NEUROSCIENCE

Cell type–specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs

(2008) Helen S Bateup et al.   NATURE NEUROSCIENCE

Recruitment of β-arrestin2 to the dopamine D2 receptor: Insights into anti-psychotic and anti-parkinsonian drug receptor signaling

(2008) I KLEWE et al.   NEUROPHARMACOLOGY

Antipsychotic Drugs: Comparison in Animal Models of Efficacy, Neurotransmitter Regulation, and Neuroprotection

(2008) J. A. Lieberman et al.   PHARMACOLOGICAL REVIEWS

Antagonism of dopamine D2 receptor/ -arrestin 2 interaction is a common property of clinically effective antipsychotics

(2008) B. Masri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA