Mode of action and resistance studies unveil new roles for tropodithietic acid as an anticancer agent and the γ-glutamyl cycle as a proton sink

CDD: NCBI's conserved domain database

(2014) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Natural products: A continuing source of novel drug leads

(2013) Gordon M. Cragg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules

(2013) P. Nonejuie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polyether ionophores—promising bioactive molecules for cancer therapy

(2012) Adam Huczyński   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Mammalian proapoptotic factor ChaC1 and its homologues function as γ-glutamyl cyclotransferases acting specifically on glutathione

(2012) Akhilesh Kumar et al.   EMBO REPORTS

Phaeobacter gallaeciensis genomes from globally opposite locations reveal high similarity of adaptation to surface life

(2012) Sebastian Thole et al.   ISME Journal

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Genomic Insights into Bacterial DMSP Transformations

(2011) Mary Ann Moran et al.   Annual Review of Marine Science

Resistance and Tolerance to Tropodithietic Acid, an Antimicrobial in Aquaculture, Is Hard To Select

(2011) Cisse Hedegaard Porsby et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tropodithietic Acid Production in Phaeobacter gallaeciensis Is Regulated by N-Acyl Homoserine Lactone-Mediated Quorum Sensing

(2011) M. Berger et al.   JOURNAL OF BACTERIOLOGY

TdaA Regulates Tropodithietic Acid Synthesis by Binding to the tdaC Promoter Region

(2011) H. Geng et al.   JOURNAL OF BACTERIOLOGY

Roseobacticides: Small Molecule Modulators of an Algal-Bacterial Symbiosis

(2011) Mohammad R. Seyedsayamdost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Jekyll-and-Hyde chemistry of Phaeobacter gallaeciensis

(2011) Mohammad R. Seyedsayamdost et al.   Nature Chemistry

Inactivation of Vibrio anguillarum by Attached and Planktonic Roseobacter Cells

(2010) P. W. D'Alvise et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Molecular mechanisms underlying roseobacter–phytoplankton symbioses

(2010) Haifeng Geng et al.   CURRENT OPINION IN BIOTECHNOLOGY

Chemoattraction to Dimethylsulfoniopropionate Throughout the Marine Microbial Food Web

(2010) J. R. Seymour et al.   SCIENCE

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

Phaeobacter and Ruegeria Species of the Roseobacter Clade Colonize Separate Niches in a Danish Turbot (Scophthalmus maximus)-Rearing Farm and Antagonize Vibrio anguillarum under Different Growth Conditions

(2008) C. H. Porsby et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Genetic Dissection of Tropodithietic Acid Biosynthesis by Marine Roseobacters

(2008) H. Geng et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Diversity, ecology, and genomics of the Roseobacter clade: a short overview

(2008) Thorsten Brinkhoff et al.   ARCHIVES OF MICROBIOLOGY

Computational Studies of the Tropone Natural Products, Thiotropocin, Tropodithietic Acid, and Troposulfenin. Significance of Thiocarbonyl−Enol Tautomerism

(2007) Edyta M. Greer et al.   JOURNAL OF ORGANIC CHEMISTRY

A fresh look at natural tropolonoids

(2007) Ronald Bentley   NATURAL PRODUCT REPORTS