The innate immune receptor Dectin-2 mediates the phagocytosis of cancer cells by Kupffer cells for the suppression of liver metastasis

CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer

(2016) Kipp Weiskopf et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunology in the liver — from homeostasis to disease

(2016) Felix Heymann et al.   Nature Reviews Gastroenterology & Hepatology

Microbially Driven TLR5-Dependent Signaling Governs Distal Malignant Progression through Tumor-Promoting Inflammation

(2015) Melanie R. Rutkowski et al.   CANCER CELL

The Nlrp3 Inflammasome Suppresses Colorectal Cancer Metastatic Growth in the Liver by Promoting Natural Killer Cell Tumoricidal Activity

(2015) Jeremy Dupaul-Chicoine et al.   IMMUNITY

C-Type Lectin Receptor MCL Facilitates Mincle Expression and Signaling through Complex Formation

(2015) Yasunobu Miyake et al.   JOURNAL OF IMMUNOLOGY

CD47 blockade triggers T cell–mediated destruction of immunogenic tumors

(2015) Xiaojuan Liu et al.   NATURE MEDICINE

Macrophages eat cancer cells using their own calreticulin as a guide: Roles of TLR and Btk

(2015) Mingye Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tissue-Specific Signals Control Reversible Program of Localization and Functional Polarization of Macrophages

(2014) Yasutaka Okabe et al.   CELL

Tumor cell-activated CARD9 signaling contributes to metastasis-associated macrophage polarization

(2014) M Yang et al.   CELL DEATH AND DIFFERENTIATION

Fungal Engagement of the C-Type Lectin Mincle Suppresses Dectin-1-Induced Antifungal Immunity

(2014) Brigitte A. Wevers et al.   Cell Host & Microbe

Platelets promote tumour metastasis via interaction between TLR4 and tumour cell-released high-mobility group box1 protein

(2014) Le-Xing Yu et al.   Nature Communications

Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses

(2014) Shiho Chiba et al.   eLife

The Multifaceted Role of the Microenvironment in Liver Metastasis: Biology and Clinical Implications

(2013) G. G. Van den Eynden et al.   CANCER RESEARCH

Siglec-h on activated microglia for recognition and engulfment of glioma cells

(2013) Jens Kopatz et al.   GLIA

C-Type Lectin Receptors Dectin-3 and Dectin-2 Form a Heterodimeric Pattern-Recognition Receptor for Host Defense against Fungal Infection

(2013) Le-Le Zhu et al.   IMMUNITY

C-type Lectin MCL Is an FcRγ-Coupled Receptor that Mediates the Adjuvanticity of Mycobacterial Cord Factor

(2013) Yasunobu Miyake et al.   IMMUNITY

Role of Dectin-2 for Host Defense against Systemic Infection with Candida glabrata

(2013) Daniela C. Ifrim et al.   INFECTION AND IMMUNITY

Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection

(2013) H. Yanai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

(2013) N. Iida et al.   SCIENCE

The innate immune response during liver inflammation and metabolic disease

(2013) Veerle Bieghs et al.   TRENDS IN IMMUNOLOGY

Signaling by Myeloid C-Type Lectin Receptors in Immunity and Homeostasis

(2012) David Sancho et al.   Annual Review of Immunology

Intravital Microscopy Through an Abdominal Imaging Window Reveals a Pre-Micrometastasis Stage During Liver Metastasis

(2012) L. Ritsma et al.   Science Translational Medicine

Eaten alive! Cell death by primary phagocytosis: ‘phagoptosis’

(2012) Guy C. Brown et al.   TRENDS IN BIOCHEMICAL SCIENCES

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

(2010) Shinobu Saijo et al.   IMMUNITY

Rapid Extravasation and Establishment of Breast Cancer Micrometastases in the Liver Microenvironment

(2010) Michelle D. Martin et al.   MOLECULAR CANCER RESEARCH

Role of activated protein C and its receptor in inhibition of tumor metastasis

(2009) M. Bezuhly et al.   BLOOD

Role of Kupffer cells in the outgrowth of colorectal cancer liver metastases

(2009) Konstantinos A. Paschos et al.   HEPATOLOGY RESEARCH

Enhanced Tumor Metastasis in Response to Blockade of the Chemokine Receptor CXCR6 Is Overcome by NKT Cell Activation

(2009) R. Cullen et al.   JOURNAL OF IMMUNOLOGY

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

(2009) Sunhwa Kim et al.   NATURE

C-type lectin Mincle is an activating receptor for pathogenic fungus,Malassezia

(2009) Sho Yamasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA