Ethanol and High Cholesterol Diet Causes Severe Steatohepatitis and Early Liver Fibrosis in Mice

Insulin receptor sensitizer, dicholine succinate, prevents both Toll-like receptor 4 (TLR4) upregulation and affective changes induced by a high-cholesterol diet in mice

(2016) Tatyana Strekalova et al.   JOURNAL OF AFFECTIVE DISORDERS

Review article: alcohol and gut microbiota - the possible role of gut microbiota modulation in the treatment of alcoholic liver disease

(2015) G. Vassallo et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Liver Fibrosis in Alcoholic Liver Disease

(2015) Bin Gao et al.   SEMINARS IN LIVER DISEASE

Mechanisms of Action of Acetaldehyde in the Up-Regulation of the Human α2(I) Collagen Gene in Hepatic Stellate Cells

(2014) Karina Reyes-Gordillo et al.   AMERICAN JOURNAL OF PATHOLOGY

Impaired VLDL assembly: a novel mechanism contributing to hepatic lipid accumulation following ovariectomy and high-fat/high-cholesterol diets?

(2014) Isabelle Côté et al.   BRITISH JOURNAL OF NUTRITION

Role of duodenal iron transporters and hepcidin in patients with alcoholic liver disease

(2014) Marketa Dostalikova-Cimburova et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

miR-33a levels in hepatic and serum after chronic HBV-induced fibrosis

(2014) Chuan-Feng Huang et al.   JOURNAL OF GASTROENTEROLOGY

Western diet in ApoE-LDLR double-deficient mouse model of atherosclerosis leads to hepatic steatosis, fibrosis and tumorigenesis

(2014) Marian Kampschulte et al.   LABORATORY INVESTIGATION

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(2014) Ruochan Chen et al.   MOLECULAR MEDICINE

Acute Ethanol Causes Hepatic Mitochondrial Depolarization in Mice: Role of Ethanol Metabolism

(2014) Zhi Zhong et al.   PLoS One

Caffeine Inhibits the Activation of Hepatic Stellate Cells Induced by Acetaldehyde via Adenosine A2A Receptor Mediated by the cAMP/PKA/SRC/ERK1/2/P38 MAPK Signal Pathway

(2014) He Wang et al.   PLoS One

Mitochondrial cholesterol accumulation in alcoholic liver disease: Role of ASMase and endoplasmic reticulum stress

(2014) Montserrat Marí et al.   Redox Biology

Ethanol and dietary unsaturated fat (corn oil/linoleic acid enriched) cause intestinal inflammation and impaired intestinal barrier defense in mice chronically fed alcohol

(2013) Irina A. Kirpich et al.   ALCOHOL

Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice

(2013) Kengo Tomita et al.   HEPATOLOGY

Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy

(2013) Virginia Hernández-Gea et al.   JOURNAL OF HEPATOLOGY

Role of Oxidative Stress and Molecular Changes in Liver Fibrosis: A Review

(2012) V. Sanchez-Valle et al.   CURRENT MEDICINAL CHEMISTRY

Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis

(2012) Christopher Savard et al.   HEPATOLOGY

Zinc and Liver Disease

(2012) Mohammad K. Mohammad et al.   NUTRITION IN CLINICAL PRACTICE

Liver Ischemia and Reperfusion Injury: New Insights into Mechanisms of Innate-Adaptive Immune-Mediated Tissue Inflammation

(2011) Y. Zhai et al.   AMERICAN JOURNAL OF TRANSPLANTATION

A High-Cholesterol Diet Exacerbates Liver Fibrosis in Mice via Accumulation of Free Cholesterol in Hepatic Stellate Cells

(2011) Toshiaki Teratani et al.   GASTROENTEROLOGY

Enteral nutrition with or without N-acetylcysteine in the treatment of severe acute alcoholic hepatitis: A randomized multicenter controlled trial

(2010) Christophe Moreno et al.   JOURNAL OF HEPATOLOGY

The translocation of HMGB1 during cell activation and cell death

(2009) Julie Gauley et al.   AUTOIMMUNITY

Mitochondrial calcium and the permeability transition in cell death

(2009) John J. Lemasters et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Chronic intake of a high-cholesterol diet resulted in hepatic steatosis, focal nodular hyperplasia and fibrosis in non-obese mice

(2009) Maho Sumiyoshi et al.   BRITISH JOURNAL OF NUTRITION

Association between dietary nutrient composition and the incidence of cirrhosis or liver cancer in the united states population

(2009) George N. Ioannou et al.   HEPATOLOGY

Betaine administration corrects ethanol-induced defective VLDL secretion

(2009) Kusum K. Kharbanda et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

(2008) Kristiaan Wouters et al.   HEPATOLOGY

NIM811 (N-Methyl-4-isoleucine Cyclosporine), a Mitochondrial Permeability Transition Inhibitor, Attenuates Cholestatic Liver Injury but Not Fibrosis in Mice

(2008) H. Rehman et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS