Enhancement of Radiation Sensitivity in Lung Cancer Cells by a Novel Small Molecule Inhibitor That Targets the β-Catenin/Tcf4 Interaction

Enrichment of the  -catenin-TCF complex at the S and G2 phases ensures cell survival and cell cycle progression

(2014) Y. Ding et al.   JOURNAL OF CELL SCIENCE

2,3,6-Trisubstituted quinoxaline derivative, a small molecule inhibitor of the Wnt/beta-catenin signaling pathway, suppresses cell proliferation and enhances radiosensitivity in A549/Wnt2 cells

(2013) Sang Bum Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Wnt Signaling Pathway in Non-Small Cell Lung Cancer

(2013) D. J. Stewart   JNCI-Journal of the National Cancer Institute

 -Catenin induces T-cell transformation by promoting genomic instability

(2013) M. Dose et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of nuclear β-catenin in rectal adenocarcinoma is associated with radioresistance

(2013) Lin Wang   WORLD JOURNAL OF GASTROENTEROLOGY

IDENTIFICATION OF CD133+/NESTIN+ PUTATIVE CANCER STEM CELLS IN NON-SMALL CELL LUNG CANCER

(2012) Maria Janikova et al.   BIOMEDICAL PAPERS-OLOMOUC

Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship

(2012) Julian R. Molina et al.   MAYO CLINIC PROCEEDINGS

Structure-Based Discovery of a Novel Inhibitor Targeting the β-Catenin/Tcf4 Interaction

(2011) Wang Tian et al.   BIOCHEMISTRY

Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy

(2011) Emil Kendziorra et al.   CARCINOGENESIS

Discovery of a novel proteasome inhibitor selective for cancer cells over non-transformed cells

(2011) Aslamuzzaman Kazi et al.   CELL CYCLE

Stem cell and lung cancer development: blaming the Wnt, Hh and Notch signalling pathway

(2011) María Rosario García Campelo et al.   Clinical & Translational Oncology

MK-1775, a Novel Wee1 Kinase Inhibitor, Radiosensitizes p53-Defective Human Tumor Cells

(2011) K. A. Bridges et al.   CLINICAL CANCER RESEARCH

Radiosensitizing Effects of Ectopic miR-101 on Non–Small-Cell Lung Cancer Cells Depend on the Endogenous miR-101 Level

(2011) Susie Chen et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers

(2011) Siwanon Jirawatnotai et al.   NATURE

Cancer Stem Cell Radioresistance and Enrichment: Where Frontline Radiation Therapy May Fail in Lung and Esophageal Cancers

(2011) Giang Huong Nguyen et al.   Cancers

Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy

(2010) James P. Sullivan et al.   CANCER AND METASTASIS REVIEWS

Tumor Cell Kill by c-MYC Depletion: Role of MYC-Regulated Genes that Control DNA Double-Strand Break Repair

(2010) K. R. Luoto et al.   CANCER RESEARCH

Chemoradiation therapy in nonsmall cell lung cancer

(2010) Paul Baas et al.   CURRENT OPINION IN ONCOLOGY

Terameprocol (Tetra-O-Methyl Nordihydroguaiaretic Acid), an Inhibitor of Sp1-Mediated Survivin Transcription, Induces Radiosensitization in Non-small Cell Lung Carcinoma

(2010) Yunguang Sun et al.   Journal of Thoracic Oncology

Improving Radiation Conformality in the Treatment of Non–Small-Cell Lung Cancer

(2010) Joe Y. Chang et al.   SEMINARS IN RADIATION ONCOLOGY

Emerging links between CDK cell cycle regulators and Wnt signaling

(2010) Gary Davidson et al.   TRENDS IN CELL BIOLOGY

Radiosensitizing Effect of YM155, a Novel Small-Molecule Survivin Suppressant, in Non-Small Cell Lung Cancer Cell Lines

(2008) T. Iwasa et al.   CLINICAL CANCER RESEARCH

Survival of the Fittest: Cancer Stem Cells in Therapeutic Resistance and Angiogenesis

(2008) Christine E. Eyler et al.   JOURNAL OF CLINICAL ONCOLOGY

Induction therapy of loco-regional non-small-cell lung cancer with reliable response and low toxicity (low dose radiotherapy sensitizes tumor to subsequent chemotherapy?)

(2008) Hiroshi Takita et al.   LUNG CANCER