Article
Ophthalmology
Fei Luo, Jie Hao, Lei Li, Jiawen Liu, Weiwei Chen, Jing Fu, Nathan Congdon
Summary: The purpose of this study was to investigate the association between refractive error, habitual accommodative tone (HAT) and the incidence and progression of myopia in Tibetan children. The results showed that baseline spherical equivalent (SE) was significantly associated with the occurrence of myopia and its progression. Additionally, lower baseline HAT was found to be potentially associated with myopic development in hyperopic children.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Article
Medicine, General & Internal
Hanyu Zhang, Carly S. Y. Lam, Wing-Chun Tang, Myra Leung, Hua Qi, Paul H. Lee, Chi-Ho To
Summary: The aim of this study is to investigate the influence of baseline relative peripheral refraction (RPR) on myopia control effects in Chinese myopic children wearing Defocus Incorporated Multiple Segments (DIMS) lenses. The results showed that baseline myopic RPR was associated with more myopic progression and greater axial elongation in the DIMS group, but not in the single vision (SV) group. Children with baseline myopic RPR in the DIMS group had statistically significant more myopia progression and axial elongation compared to those with baseline hyperopic RPR.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Ophthalmology
Chia-Wei Lee, Chi-Chen Chiang, Der-Chong Tsai, Ching-Yao Tsai, Yiing Mei Liou
Summary: This population-based cohort study aimed to investigate the incidence rate and risk factors for anisometropia among young schoolchildren in Taipei City. The results showed an annual incidence rate of 3.8% for anisometropia. Baseline spherical equivalent and female sex were significantly associated with incident anisometropia. Among lifestyle risk factors, less time spent outdoors and shorter eye-to-object distances during near work increased the risk of incident anisometropia.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Medicine, General & Internal
Aparna Gopalakrishnan, Jameel Rizwana Hussaindeen, Viswanathan Sivaraman, Meenakshi Swaminathan, Yee Ling Wong, James Andrew Armitage, Alex Gentle, Simon Backhouse
Summary: This study aimed to compare the agreement between cycloplegic and non-cycloplegic autorefraction and establish a myopia threshold. The results showed that non-cycloplegic refraction underestimates hyperopia and overestimates myopia, but the difference is minimal and not clinically significant for myopic subjects. A threshold of SE <= -0.75 D for defining myopia prevalence using non-cycloplegic refraction is comparable to the standard definition of SE <= -0.50 D for cycloplegic myopic refraction.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Ophthalmology
Ian Flitcroft, John Ainsworth, Audrey Chia, Susan Cotter, Elise Harb, Zi-Bing Jin, Caroline C. W. Klaver, Anthony T. Moore, Ken K. Nischal, Kyoko Ohno-Matsui, Evelyn A. Paysse, Michael X. Repka, Irina Y. Smirnova, Martin Snead, Virginie J. M. Verhoeven, Pavan K. Verkicharla
Summary: The purpose of this study was to evaluate the epidemiology, etiology, clinical assessment, investigation, management, and visual consequences of high myopia in infants and young children. The findings suggest that high myopia is rare in pre-school children, with a prevalence less than 1%. The etiology of myopia in these children differs from older children, with a high rate of secondary myopia associated with prematurity or genetic causes. The clinical management of high myopia in infants and young children is complex and often requires a multidisciplinary approach, including investigation, optical correction, and myopia control treatments.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Article
Medicine, General & Internal
Ning-Yi Hsia, Li-Yen Wen, Ching-Ying Chou, Cheng-Li Lin, Lei Wan, Hui-Ju Lin
Summary: This study found that children with ptosis have a higher risk of astigmatism, myopia, hyperopia, and amblyopia. Children diagnosed with ptosis at an age older than 3 years have a higher risk of myopia than those diagnosed before the age of 3. However, there is no significant difference in the risk of astigmatism, amblyopia, and hyperopia between different age groups.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Wenzheng Du, Gang Ding, Xiying Guo, Kadiya Abudukeyimu, Yanzhu Wang, Lijun Wang, Xiaoli Qi, Yuxian Ning, Ning Hua, Linlin Song, Xue Li, Jing Li, Ying Zhang, Nan Wei, Xuehan Qian
Summary: Investigated the associations between anthropometric indicators and refraction in school-aged children post-COVID-19. Analyzing data from 25,644 children aged 7 to 12 years in 48 elementary schools in Tianjin, it was found that height, weight, and blood pressure were correlated with refraction. Changes in height and weight were also correlated with changes in refraction. Therefore, children's height, weight, and growth rate can be used as reference indicators for predicting myopia risk and monitoring myopia progression.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Ophthalmology
Zhenghua Lin, Xiaoyun Xi, Longbo Wen, Zhiwei Luo, Pablo Artal, Zhikuan Yang, Weizhong Lan
Summary: This study investigates the role of peripheral refraction in children's myopization. The results show that the distribution of refraction across the retina is significantly different in children who were initially emmetropic. Specifically, myopia in the superior retina is correlated with central myopic shift. Changes in relative peripheral refraction are more likely a consequence of myopia progression rather than a cause.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Article
Public, Environmental & Occupational Health
Wenjing Wang, Shuzhen Peng, Faxue Zhang, Boya Zhu, Longjiang Zhang, Xiaodong Tan
Summary: This study investigated the changes in vision among children before and after the COVID-19 pandemic. It found an increase in myopia prevalence among younger children, but slight improvement in vision in 2021. These results suggest the need to focus on vision prevention and control in preschool-aged children even after the pandemic.
INTERNATIONAL JOURNAL OF PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Kiwako Mori, Hidemasa Torii, Yutaka Hara, Michiko Hara, Erisa Yotsukura, Akiko Hanyuda, Kazuno Negishi, Toshihide Kurihara, Kazuo Tsubota
Summary: The study found through a double-blinded randomized clinical trial that violet light-transmitting eyeglasses (VL glasses) have a suppressive effect on myopia in children, particularly in those with shorter near-work time and those who had never worn eyeglasses before the trial. The axial elongation suppressive rate in the VL glasses group was 21.4% over two years.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Ophthalmology
Meng-Tian Kang, Catherine Jan, ShiMing Li, Mayinuer Yusufu, Xintong Liang, Kai Cao, Luo-Ru Liu, He Li, Ningli Wang, Nathan Congdon
Summary: Pseudomyopia is more common in younger, more hyperopic children. Only a small percentage of optometry stores use cycloplegia for refracting children, indicating potential need for wider adoption of this practice.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Ophthalmology
W. Neil Charman, Hema Radhakrishnan
Summary: This study aims to better understand the development of juvenile myopia in the context of overall refractive development during childhood. It suggests more informative ways of analyzing relevant data, particularly in relation to early identification of children who are likely to become markedly myopic and would benefit from myopia control.
CONTACT LENS & ANTERIOR EYE
(2022)
Article
Orthopedics
Jidapa Wongcharoenwatana, Jariya Tarugsa, Kamolporn Kaewpornsawan, Perajit Eamsobhana, Chatupon Chotigavanichaya, Thanase Ariyawatkul
Summary: This study evaluated the characteristics of abused children, families, and abusive events, identifying child age and abusive parents as risk factors associated with recurrence of child abuse. Prompt intervention based on these risk factors could help recognize children at risk of abuse.
JOURNAL OF ORTHOPAEDIC SURGERY
(2021)
Article
Endocrinology & Metabolism
Tran Quang Binh, Pham Tran Phuong, Nguyen Thanh Chung, Bui Thi Nhung, Do Dinh Tung, Duong Tuan Linh, Tran Ngoc Luong, Le Danh Tuyen
Summary: The study aimed to identify an easily applicable nomogram for detecting undiagnosed type 2 diabetes in high-risk individuals. By developing and validating nomograms in both regional and national populations, it was found that the non-lab nomogram had a higher area under the receiver operating characteristic curve.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Review
Medicine, General & Internal
Hou-Ren Tsai, Tai-Li Chen, Jen-Hung Wang, Huei-Kai Huang, Cheng-Jen Chiu
Summary: This study investigated the efficacy and safety of 0.01% atropine in slowing axial elongation in children with myopia, finding that it significantly slowed the progression of refraction and axial length over a 1-year period with no significant adverse effects.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Ophthalmology
Xianwen Shang, Zhuoting Zhu, Yu Huang, Xueli Zhang, Wei Wang, Danli Shi, Yu Jiang, Xiaohong Yang, Mingguang He
Summary: This study aimed to investigate the independent and interactive associations of ophthalmic and systemic conditions with incident dementia. The findings revealed that age-related macular degeneration, cataract, and diabetes-related eye disease were associated with an increased risk of dementia. Individuals with both ophthalmic and systemic conditions had a higher risk of dementia.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Dolly Shuo-Teh Chang, Yuzhen Jiang, Julia Anne Kim, Shengsong Huang, Beatriz Munoz, Tin Aung, Mingguang He, Paul J. Foster, David Friedman
Summary: This study assessed the long-term impact of laser peripheral iridotomy (LPI) on cataract formation in Chinese primary angle-closure suspect (PACS) patients. The results showed that LPI treatment did not cause significant cataract progression and did not increase the risk of developing clinically meaningful cataract worsening over time.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Xiangui He, Padmaja Sankaridurg, Jingjing Wang, Jun Chen, Thomas Naduvilath, Mingguang He, Zhuoting Zhu, Wayne Li, Ian G. Morgan, Shuyu Xiong, Jianfeng Zhu, Haidong Zou, Kathryn A. Rose, Bo Zhang, Rebecca Weng, Serge Resnikoff, Xun Xu
Summary: The study aimed to evaluate the efficacy of time spent outdoors per school day on myopia onset and shift. The results showed that increasing outdoor time reduced the risk of myopia, especially in nonmyopic children. The protective effect was related to the duration of exposure and light intensity.
Article
Ophthalmology
Ruilin Xiong, Zhuoting Zhu, Yu Jiang, Xiangbin Kong, Jian Zhang, Wei Wang, Katerina Kiburg, Yixiong Yuan, Yanping Chen, Shiran Zhang, Meng Xuan, Junwen Zeng, Ian G. Morgan, Mingguang He
Summary: This study evaluated the long-term efficacy and safety of repeated low-level red-light therapy for myopia control in children. The results showed that continued RLRL therapy had promising effects in slowing myopia progression, but a modest rebound effect was noted after treatment cessation.
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2022)
Article
Medicine, Research & Experimental
Kate Thomson, Cindy Karouta, Faran Sabeti, Nicola Anstice, Myra Leung, Tina Jong, Ted Maddess, Ian G. Morgan, Jeremy Game, Regan Ashby
Summary: This study reports on the safety profile of a novel dopamine-based ophthalmic treatment for myopia, levodopa/carbidopa eye drops. The results suggest that topical levodopa/carbidopa is safe and tolerable to the eye, paving the way for future studies on the efficacy of this novel ophthalmic formulation in the treatment of human myopia.
CTS-CLINICAL AND TRANSLATIONAL SCIENCE
(2022)
Article
Ophthalmology
Wei Wang, Yu Jiang, Zhuoting Zhu, Shiran Zhang, Meng Xuan, Yanping Chen, Ruilin Xiong, Gabriella Bulloch, Junwen Zeng, Ian G. G. Morgan, Mingguang He
Summary: This study evaluated the frequency and associated factors of clinically significant axial length shortening among myopic children following repeated low-level red light therapy. The findings showed that more than a quarter of children had axial length shortening > 0.05 mm following the therapy, with an overall mean axial length change of -0.142 mm/year. Further studies are needed to explore the underlying mechanisms of axial length shortening.
OPHTHALMOLOGY AND THERAPY
(2023)
Article
Public, Environmental & Occupational Health
Jingjing Wang, Padmaja Sankaridurg, Thomas Naduvilath, Wayne Li, Ian G. Morgan, Kathryn A. Rose, Rebecca Weng, Xun Xu, Xiangui He
Summary: This study investigates the relationship between outdoor time and academic performance among school-aged children. It found that outdoor time and sleep duration were non-linearly associated with academic performance, suggesting that promoting outdoor time may not have a negative impact on academic performance.
Article
Medicine, General & Internal
Jingjing Feng, Catherine Jan, Yaguang Peng, Mingguang He, Lei An, Leilei Zhan, Wei Shi, Xiaoxia Peng, Wenhan Shang, Wei Li, Xiao Xu, Li Yao
Summary: This study evaluated the benefits of cataract surgery for patients and made recommendations for Chinese national health policy makers based on the quality of cataract treatments. Using real-world data, an observational study was conducted. The results found that various factors influenced the improvement of visual acuity after surgery. Overall, the study is important for informing health policy decisions.
Editorial Material
Medicine, General & Internal
Ian G. Morgan
Article
Medicine, Research & Experimental
Kate Thomson, Cindy Karouta, Daniel Weber, Nichola Hoffmann, Ian Morgan, Tamsin Kelly, Regan Ashby
Summary: Atropine, a commonly used drug for myopia treatment, inhibits the development of myopia by modulating serotonin receptor activity. This finding suggests the potential use of atropine in combination with serotonergic signaling regulation therapy for treating myopia.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Editorial Material
Ophthalmology
Ian G. Morgan, Weizhong Lan
Article
Ophthalmology
Xiaohu Ding, Ian G. Morgan, Yin Hu, Xianghua Tang, Jiayu Zhang, Lan Guo, Yangfeng Guo, Nali Deng, Xueying Du, Yingfeng Zheng, Mingguang He, Ciyong Lu, Xiao Yang, Yizhi Liu
Summary: The purpose of this study is to distinguish the effects of age and grade on the development of myopia. The data of Grade 1 and Grade 2 students in 2018 and 2019 were examined, and regression analysis and regression discontinuity analysis were used to assess the development of refraction. The results indicate that grade increase has a more significant impact on the myopic shift than age.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Article
Ophthalmology
Yanxian Chen, Cheng Tan, Li-Lian Foo, Siyan He, Jian Zhang, Gabriella Bulloch, Seang-Mei Saw, Jinying Li, Ian Morgan, Xiaobo Guo, Mingguang He
Summary: This study developed and validated models to predict the development of myopia based on cycloplegic refraction or ocular biometry. The study identified thresholds of premyopia and found that cycloplegic refraction at baseline is a better predictor of myopia onset compared to other ocular biometric measurements. The findings suggest that premyopia can be successfully defined and used to predict the need for more aggressive myopia prophylaxis.
ASIA-PACIFIC JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Danli Shi, Weiyi Zhang, Shuang He, Yanxian Chen, Fan Song, Shunming Liu, Ruobing Wang, Yingfeng Zheng, Mingguang He
Summary: This study developed a deep learning model that can transform color fundus photography into corresponding venous and late-phase fundus fluorescein angiography images. The model was validated on multiple datasets and showed promising results for diagnosing diabetic retinopathy and diabetic macular edema.
OPHTHALMOLOGY SCIENCE
(2023)
Article
Ophthalmology
Shengsong Xu, Jinyun Jiang, Mengting Yu, Jiajia Gao, Mengyi Wang, Longhao Kuang, Yin Hu, Chea-su Kee, Xiao Yang, Mingguang He
Summary: This study investigated the impact of COVID-19 home confinement on the effectiveness of interventions for controlling myopia. The results suggest that ortho-k may be a better therapy for children in this high-risk environment.
ACTA OPHTHALMOLOGICA
(2023)