Anti-Tumor Effects of Second Generation β-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression

Aspartate β-hydroxylase expression promotes a malignant pancreatic cellular phenotype

(2015) Xiaoqun Dong et al.   Oncotarget

Mutations in ASPH Cause Facial Dysmorphism, Lens Dislocation, Anterior-Segment Abnormalities, and Spontaneous Filtering Blebs, or Traboulsi Syndrome

(2014) Nisha Patel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

LRH1 promotes pancreatic cancer metastasis

(2014) Qiushi Lin et al.   CANCER LETTERS

Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET

(2014) Erinn B. Rankin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gas6/Axl mediates tumor cell apoptosis, migration and invasion and predicts the clinical outcome of osteosarcoma patients

(2013) Ju Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Suppression of Androgen Receptor Enhances the Self-renewal of Mesenchymal Stem Cells Through Elevated Expression of EGFR

(2013) Chiung-Kuei Huang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Critical Role for Notch Signaling in the Formation of Cholangiocellular Carcinomas

(2013) Steffen Zender et al.   CANCER CELL

Cell Lineage Tracing Reveals a Biliary Origin of Intrahepatic Cholangiocarcinoma

(2013) R. V. Guest et al.   CANCER RESEARCH

Pharmacological Inactivation of Skp2 SCF Ubiquitin Ligase Restricts Cancer Stem Cell Traits and Cancer Progression

(2013) Chia-Hsin Chan et al.   CELL

Notch Pathway Activity Identifies Cells with Cancer Stem Cell-like Properties and Correlates with Worse Survival in Lung Adenocarcinoma

(2013) K. A. Hassan et al.   CLINICAL CANCER RESEARCH

Hepatocytes as a source of cholangiocytes in injured liver

(2013) Frédéric P. Lemaigre   HEPATOLOGY

Side population cell fractions from hepatocellular carcinoma cell lines increased with tumor dedifferentiation, but lack characteristic features of cancer stem cells

(2013) Masamichi Nakayama et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers

(2013) Waraporn Chan-on et al.   NATURE GENETICS

KrasG12D and p53 Mutation Cause Primary Intrahepatic Cholangiocarcinoma

(2012) M. R. O'Dell et al.   CANCER RESEARCH

Targeting androgen receptor in bone marrow mesenchymal stem cells leads to better transplantation therapy efficacy in liver cirrhosis

(2012) Chiung-Kuei Huang et al.   HEPATOLOGY

Endothelial Cells Create a Stem Cell Niche in Glioblastoma by Providing NOTCH Ligands That Nurture Self-Renewal of Cancer Stem-Like Cells

(2011) T. S. Zhu et al.   CANCER RESEARCH

Not(ch) just development: Notch signalling in the adult brain

(2011) Jessica L. Ables et al.   NATURE REVIEWS NEUROSCIENCE

siRNA inhibition of aspartyl-asparaginyl β-hydroxylase expression impairs cell motility, Notch signaling, and fetal growth

(2011) Fusun Gundogan et al.   PATHOLOGY RESEARCH AND PRACTICE

Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver

(2010) S. Benhamouche et al.   GENES & DEVELOPMENT

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

Prognostic value of aspartyl (asparaginyl)-β-hydroxylase/humbug expression in non–small cell lung carcinoma

(2009) Martin Luu et al.   HUMAN PATHOLOGY

Risk of hepatobiliary and pancreatic cancers after hepatitis C virus infection: A population-based study of U.S. veterans

(2008) Hashem B. El-Serag et al.   HEPATOLOGY

Efficient tumour formation by single human melanoma cells

(2008) Elsa Quintana et al.   NATURE