Inhibition of CXCR4 by LY2624587, a Fully Humanized Anti-CXCR4 Antibody Induces Apoptosis of Hematologic Malignancies

Antileukemia activity of the novel peptidic CXCR4 antagonist LY2510924 as monotherapy and in combination with chemotherapy

(2015) B.-S. Cho et al.   BLOOD

CXCR4/CXCL12 Mediate Autocrine Cell- Cycle Progression in NF1-Associated Malignant Peripheral Nerve Sheath Tumors

(2013) Wei Mo et al.   CELL

Targeting the CD20 and CXCR4 Pathways in Non-Hodgkin Lymphoma with Rituximab and High-Affinity CXCR4 Antagonist BKT140

(2013) K. Beider et al.   CLINICAL CANCER RESEARCH

The High-Affinity CXCR4 Antagonist BKT140 Is Safe and Induces a Robust Mobilization of Human CD34+ Cells in Patients with Multiple Myeloma

(2013) A. Peled et al.   CLINICAL CANCER RESEARCH

CXCR4-SERINE339 regulates cellular adhesion, retention and mobilization and is a marker for poor prognosis in acute myeloid leukemia

(2013) L Brault et al.   LEUKEMIA

High CXCR4 and low VLA-4 expression predicts poor survival in adults with acute lymphoblastic leukemia

(2013) Sun-Young Ko et al.   LEUKEMIA RESEARCH

Small Molecule Inhibitors of CXCR4

(2013) Bikash Debnath et al.   Theranostics

BMS-936564/MDX-1338: A Fully Human Anti-CXCR4 Antibody Induces Apoptosis In Vitro and Shows Antitumor Activity In Vivo in Hematologic Malignancies

(2012) M. R. Kuhne et al.   CLINICAL CANCER RESEARCH

High-content multiplexed tissue imaging and quantification for cancer drug discovery

(2012) Beverly L. Falcon et al.   DRUG DISCOVERY TODAY

A review on CXCR4/CXCL12 axis in oncology: No place to hide

(2012) Urszula M. Domanska et al.   EUROPEAN JOURNAL OF CANCER

Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4)

(2012) Shinya Oishi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model

(2012) Y Zhang et al.   Cell Death & Disease

Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia

(2011) K. O'Callaghan et al.   BLOOD

RNAi Targeting CXCR4 Inhibits Tumor Growth Through Inducing Cell Cycle Arrest and Apoptosis

(2011) Tao Yu et al.   MOLECULAR THERAPY

The Cyclic Pentapeptide d-Arg3FC131, a CXCR4 Antagonist, Induces Apoptosis of Somatotrope Tumor and Inhibits Tumor Growth in Nude Mice

(2010) Jeong Mo Kim et al.   ENDOCRINOLOGY

Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice

(2010) Mitomu Kioi et al.   JOURNAL OF CLINICAL INVESTIGATION

Successful Stem Cell Remobilization Using Plerixafor (Mozobil) Plus Granulocyte Colony-Stimulating Factor in Patients with Non-Hodgkin Lymphoma: Results from the Plerixafor NHL Phase 3 Study Rescue Protocol

(2009) Ivana N. Micallef et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy

(2009) A. K. Azab et al.   BLOOD

An antagonist of the chemokine receptor CXCR4 induces mitotic catastrophe in ovarian cancer cells

(2009) J. Kwong et al.   MOLECULAR CANCER THERAPEUTICS

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

(2008) Z. Zeng et al.   BLOOD

Prognostic value of CXCR4 and FAK expression in acute myelogenous leukemia

(2008) Emmanuelle Tavernier-Tardy et al.   LEUKEMIA RESEARCH

The roles of chemokine CXCL12 in embryonic and brain tumor angiogenesis

(2008) Meizhang Li et al.   SEMINARS IN CANCER BIOLOGY