Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa

Antimicrobial interactions: mechanisms and implications for drug discovery and resistance evolution

(2015) Tobias Bollenbach   CURRENT OPINION IN MICROBIOLOGY

A new antibiotic kills pathogens without detectable resistance

(2015) Losee L. Ling et al.   NATURE

PheNetic: network-based interpretation of molecular profiling data

(2015) Dries De Maeyer et al.   NUCLEIC ACIDS RESEARCH

The Evolving Role of Chemical Synthesis in Antibacterial Drug Discovery

(2014) Peter M. Wright et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Identification and characterization of an anti-pseudomonal dichlorocarbazol derivative displaying anti-biofilm activity

(2014) Veerle Liebens et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Evaluation of the Toxicity of 5-Aryl-2-Aminoimidazole-Based Biofilm Inhibitors against Eukaryotic Cell Lines, Bone Cells and the Nematode Caenorhabditis elegans

(2014) Hans Steenackers et al.   MOLECULES

A putative de-N-acetylase of the PIG-L superfamily affects fluoroquinolone tolerance inPseudomonas aeruginosa

(2014) Veerle Liebens et al.   Pathogens and Disease

Design and synthesis of cationic antibacterial peptide based on Leucrocin I sequence, antibacterial peptide from crocodile (Crocodylus siamensis) white blood cell extracts

(2013) Nualyai Yaraksa et al.   JOURNAL OF ANTIBIOTICS

Antibiotics in the clinical pipeline in 2013

(2013) Mark S Butler et al.   JOURNAL OF ANTIBIOTICS

Functional characterization of the NfxB repressor of the mexCD-oprJ multidrug efflux operon of Pseudomonas aeruginosa

(2013) A. Purssell et al.   MICROBIOLOGY-SGM

Two Hits Are Better than One: Membrane-Active and DNA Binding-Related Double-Action Mechanism of NK-18, a Novel Antimicrobial Peptide Derived from Mammalian NK-Lysin

(2012) Jiexi Yan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Target of Daptomycin Is Absent from Escherichia coli and Other Gram-Negative Pathogens

(2012) Christopher P. Randall et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Transposon library screening for identification of genetic loci participating in intrinsic susceptibility and acquired resistance to antistaphylococcal agents

(2012) K. L. Blake et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

(2012) Anna E Grzegorzewicz et al.   Nature Chemical Biology

Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections in Adults and Children

(2011) Catherine Liu et al.   CLINICAL INFECTIOUS DISEASES

Attenuation of Colistin Bactericidal Activity by High Inoculum of Pseudomonas aeruginosa Characterized by a New Mechanism-Based Population Pharmacodynamic Model

(2010) J. B. Bulitta et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

Resistance to polymyxins: Mechanisms, frequency and treatment options

(2010) Matthew E. Falagas et al.   DRUG RESISTANCE UPDATES

Mutation ofnfxBCauses Global Changes in the Physiology and Metabolism ofPseudomonas aeruginosa

(2010) Hannah G. Stickland et al.   JOURNAL OF PROTEOME RESEARCH

Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections

(2010) Julian G. Hurdle et al.   NATURE REVIEWS MICROBIOLOGY

Pseudomonas Genome Database: improved comparative analysis and population genomics capability for Pseudomonas genomes

(2010) G. L. Winsor et al.   NUCLEIC ACIDS RESEARCH

Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa

(2010) N. Srinivas et al.   SCIENCE

A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

(2010) Kevin Pethe et al.   Nature Communications

Vancomycin in Combination with Other Antibiotics for the Treatment of Serious Methicillin‐ResistantStaphylococcus aureusInfections

(2009) Stan Deresinski   CLINICAL INFECTIOUS DISEASES

Antifungal Carbazoles

(2009) Karin Thevissen et al.   CURRENT MEDICINAL CHEMISTRY

XF-73, a novel antistaphylococcal membrane-active agent with rapid bactericidal activity

(2009) N. Ooi et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Pseudomonas aeruginosa – a phenomenon of bacterial resistance

(2009) Tanya Strateva et al.   JOURNAL OF MEDICAL MICROBIOLOGY

The RAST Server: Rapid Annotations using Subsystems Technology

(2008) Ramy K Aziz et al.   BMC GENOMICS

Consequences of daptomycin-mediated membrane damage in Staphylococcus aureus

(2008) J. K. Hobbs et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

STRING 8--a global view on proteins and their functional interactions in 630 organisms

(2008) L. J. Jensen et al.   NUCLEIC ACIDS RESEARCH