An Open-Label Trial of 12-Week Simeprevir plus Peginterferon/Ribavirin (PR) in Treatment-Naïve Patients with Hepatitis C Virus (HCV) Genotype 1 (GT1)

Virology analyses of HCV isolates from genotype 1-infected patients treated with simeprevir plus peginterferon/ribavirin in Phase IIb/III studies

(2015) Oliver Lenz et al.   JOURNAL OF HEPATOLOGY

Simeprevir With Peginterferon and Ribavirin Leads to High Rates of SVR in Patients With HCV Genotype 1 Who Relapsed After Previous Therapy: A Phase 3 Trial

(2014) Xavier Forns et al.   GASTROENTEROLOGY

Simeprevir with peginterferon/ribavirin for treatment-naïve hepatitis C genotype 1 patients in Japan: CONCERTO-1, a phase III trial

(2014) Norio Hayashi et al.   JOURNAL OF HEPATOLOGY

P1127 SIMEPREVIR (TMC435) WITH PEGINTERFERON/RIBAVIRIN FOR TREATMENT OF CHRONIC HCV GENOTYPE 1 INFECTION IN TREATMENT-NAIVE EUROPEAN PATIENTS IN THE QUEST-1 AND QUEST-2 PHASE III TRIALS

(2014) G.R. Foster et al.   JOURNAL OF HEPATOLOGY

Simeprevir with peginterferon/ribavirin for treatment of chronic hepatitis C virus genotype 1 infection: pooled safety analysis from Phase IIb and III studies

(2014) M. P. Manns et al.   JOURNAL OF VIRAL HEPATITIS

Simeprevir with pegylated interferon alfa 2a plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-1): a phase 3, randomised, double-blind, placebo-controlled trial

(2014) Ira M Jacobson et al.   LANCET

Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial

(2014) Michael Manns et al.   LANCET

881 HIGH SVR RATES (SVR4) FOR 12-WEEK TOTAL TELAPREVIR COMBINATION THERAPY IN IL28B CC TREATMENT-NAÏVES AND PRIOR RELAPSERS WITH G1 CHRONIC HEPATITIS C: CONCISE INTERIM ANALYSIS

(2013) D.R. Nelson et al.   JOURNAL OF HEPATOLOGY

Sofosbuvir for Previously Untreated Chronic Hepatitis C Infection

(2013) Eric Lawitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sustained Virologic Response to Antiviral Therapy for Chronic Hepatitis C Virus Infection: A Cure and So Much More

(2011) B. L. Pearlman et al.   CLINICAL INFECTIOUS DISEASES

An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases

(2011) Marc G. Ghany et al.   HEPATOLOGY

1167 COST BENEFIT ANALYSIS OF RESPONSE GUIDED THERAPY: DYNAMIC DISEASE MARKOV MODELING FOR PATIENTS WITH CHRONIC HEPATITIS (HCV) BY FIBROSIS STAGES

(2011) P. McEwan et al.   JOURNAL OF HEPATOLOGY

IL28B SNP rs12979860 Is a Critical Predictor for On-Treatment and Sustained Virologic Response in Patients with Hepatitis C Virus Genotype-1 Infection

(2011) Chun-Yen Lin et al.   PLoS One

Eradication of Hepatitis C Virus in Patients Successfully Treated for Chronic Hepatitis C

(2008) Sarah Maylin et al.   GASTROENTEROLOGY

Expert opinion on the treatment of patients with chronic hepatitis C

(2008) S. Zeuzem et al.   JOURNAL OF VIRAL HEPATITIS