Second Generation Amphiphilic Poly-Lysine Dendrons Inhibit Glioblastoma Cell Proliferation without Toxicity for Neurons or Astrocytes
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Title
Second Generation Amphiphilic Poly-Lysine Dendrons Inhibit Glioblastoma Cell Proliferation without Toxicity for Neurons or Astrocytes
Authors
Keywords
Small interfering RNAs, Glioblastoma cells, Mitochondria, Toxicity, Neurons, Astrocytes, High performance liquid chromatography, Nanoparticles
Journal
PLoS One
Volume 11, Issue 11, Pages e0165704
Publisher
Public Library of Science (PLoS)
Online
2016-11-11
DOI
10.1371/journal.pone.0165704
References
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- (2010) K. T. Al-Jamal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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