Up-Regulation of CYP2C19 Expression by BuChang NaoXinTong via PXR Activation in HepG2 Cells

Identification of key active constituents of Buchang Naoxintong capsules with therapeutic effects against ischemic stroke by using an integrative pharmacology-based approach

(2016) Xu Haiyu et al.   Molecular BioSystems

Influence ofCYP2C19loss-of-function variants on the metabolism of clopidogrel in patients from north-western China

(2015) R. Lin et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Characterization and rapid identification of chemical constituents of NaoXinTong capsules by UHPLC-linear ion trap/Orbitrap mass spectrometry

(2015) Wang Songsong et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

A randomized controlled trial of adjunctive Bunchang Naoxintong Capsule (步长脑心通胶囊) versus maintenance dose clopidogrel in patients with CYP2C19*2 polymorphism

(2014) Hui Chen et al.   Chinese Journal of Integrative Medicine

BNC Protects H9c2 Cardiomyoblasts from H2O2-Induced Oxidative Injury through ERK1/2 Signaling Pathway

(2013) Fangbo Zhang et al.   Evidence-based Complementary and Alternative Medicine

In Vitro Assessment of Cytochrome P450 2C19 Potential of Naoxintong

(2012) Hui Chen et al.   Evidence-based Complementary and Alternative Medicine

CAR-mediated Up-regulation of CYP3A4 Expression in LS174T Cells by Chinese Herbal Compounds

(2011) Ling Huang et al.   Drug Metabolism and Pharmacokinetics

Comparison of Adjunctive Naoxintong versus Clopidogrel in Volunteers with the CYP2C19*2 Gene Mutation Accompanied with Qi Deficiency and Blood Stasis Constitution

(2011) Hui Chen et al.   Evidence-based Complementary and Alternative Medicine

Identification of novel pregnane X receptor activators from traditional Chinese medicines

(2011) Chunna Yu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes

(2010) L. Guo et al.   DRUG METABOLISM AND DISPOSITION

Hepatocyte Nuclear Factor 4  Regulates Rifampicin-Mediated Induction of CYP2C Genes in Primary Cultures of Human Hepatocytes

(2010) R. Rana et al.   DRUG METABOLISM AND DISPOSITION

A Comparison of Whole Genome Gene Expression Profiles of HepaRG Cells and HepG2 Cells to Primary Human Hepatocytes and Human Liver Tissues

(2010) S. N. Hart et al.   DRUG METABOLISM AND DISPOSITION

Synergistically Enhanced CYP2B6 Inducibility between a Polymorphic Mutation in CYP2B6 Promoter and Pregnane X Receptor Activation

(2010) H. Li et al.   MOLECULAR PHARMACOLOGY

Cytochrome P450 Genetic Polymorphisms and the Response to Prasugrel

(2009) Jessica L. Mega et al.   CIRCULATION

Association of Cytochrome P450 2C19 Genotype With the Antiplatelet Effect and Clinical Efficacy of Clopidogrel Therapy

(2009) Alan R. Shuldiner   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Danqi Piantang Jiaonang (DJ), a Traditional Chinese Medicine, in Poststroke Recovery

(2009) Christopher Chen et al.   STROKE

PXR-mediated transcriptional activation of CYP3A4 by cryptotanshinone and tanshinone IIA

(2008) Chunna Yu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study

(2008) Jean-Philippe Collet et al.   LANCET

Cytochrome P-450 Polymorphisms and Response to Clopidogrel

(2008) Jessica L. Mega et al.   NEW ENGLAND JOURNAL OF MEDICINE