Validation of Synthetic CRISPR Reagents as a Tool for Arrayed Functional Genomic Screening

Tankyrase Inhibitor Sensitizes Lung Cancer Cells to Endothelial Growth Factor Receptor (EGFR) Inhibition via Stabilizing Angiomotins and Inhibiting YAP Signaling

(2016) Hui Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer

(2016) Mark L. McCleland et al.   JOURNAL OF CLINICAL INVESTIGATION

A CRISPR screen defines a signal peptide processing pathway required by flaviviruses

(2016) Rong Zhang et al.   NATURE

Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

(2016) Caleb D. Marceau et al.   NATURE

CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes

(2016) Bastiaan Evers et al.   NATURE BIOTECHNOLOGY

Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting

(2016) A. J. Aguirre et al.   Cancer Discovery

TRAIP is involved in chromosome alignment and SAC regulation in mouse oocyte meiosis

(2016) Yi-Feng Yuan et al.   Scientific Reports

A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells

(2016) Judd F. Hultquist et al.   Cell Reports

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics

(2016) George Savidis et al.   Cell Reports

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62

(2016) Rowena DeJesus et al.   eLife

A genome-scale CRISPR-Cas9 screening method for protein stability reveals novel regulators of Cdc25A

(2016) Yuanzhong Wu et al.   Cell Discovery

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

(2015) Traver Hart et al.   CELL

Genetic screens and functional genomics using CRISPR/Cas9 technology

(2015) Ella Hartenian et al.   FEBS Journal

Identification and characterization of essential genes in the human genome

(2015) T. Wang et al.   SCIENCE

Synthesis of an arrayed sgRNA library targeting the human genome

(2015) Tobias Schmidt et al.   Scientific Reports

A CRISPR-Based Screen Identifies Genes Essential for West-Nile-Virus-Induced Cell Death

(2015) Hongming Ma et al.   Cell Reports

TRAIP is a regulator of the spindle assembly checkpoint

(2014) C. Chapard et al.   JOURNAL OF CELL SCIENCE

Computational detection and suppression of sequence-specific off-target phenotypes from whole genome RNAi screens

(2014) Rui Zhong et al.   NUCLEIC ACIDS RESEARCH

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

(2013) Hiroko Koike-Yusa et al.   NATURE BIOTECHNOLOGY

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Genetic Screens in Human Cells Using the CRISPR-Cas9 System

(2013) Tim Wang et al.   SCIENCE

An Arrayed Genome-Scale Lentiviral-Enabled Short Hairpin RNA Screen Identifies Lethal and Rescuer Gene Candidates

(2012) Bhavneet Bhinder et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens

(2012) Frederic D Sigoillot et al.   NATURE METHODS

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Fast and SNP-tolerant detection of complex variants and splicing in short reads

(2010) T. D. Wu et al.   BIOINFORMATICS

Selective Killing of Cancer Cells by Suppression of Geminin Activity

(2009) W. Zhu et al.   CANCER RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH