A Systematic Investigation into Aging Related Genes in Brain and Their Relationship with Alzheimer’s Disease

Inflammaging: disturbed interplay between autophagy and inflammasomes

(2016) Antero Salminen et al.   Aging-US

Age-related increase of VGF-expression in T lymphocytes

(2016) Stefan Busse et al.   Aging-US

Condition-specific target prediction from motifs and expression

(2014) Guofeng Meng et al.   BIOINFORMATICS

The good and the bad of being connected: the integrons of aging

(2014) Andrew Dillin et al.   CURRENT OPINION IN CELL BIOLOGY

Intrinsic TGF-β signaling promotes age-dependent CD8+ T cell polyfunctionality attrition

(2014) Rajarshi Bhadra et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcriptional activation of p21WAF1/CIP1 is mediated by increased DNA binding activity and increased interaction between p53 and Sp1 via phosphorylation during replicative senescence of human embryonic fibroblasts

(2014) Hyun-Seok Kim et al.   MOLECULAR BIOLOGY REPORTS

Brain tumor senescence might be mediated by downregulation of S-phase kinase-associated protein 2 via butylidenephthalide leading to decreased cell viability

(2014) Mao-Hsuan Huang et al.   TUMOR BIOLOGY

Age-related variations in the methylome associated with gene expression in human monocytes and T cells

(2014) Lindsay M. Reynolds et al.   Nature Communications

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Stressing the cell cycle in senescence and aging

(2013) Hollie Chandler et al.   CURRENT OPINION IN CELL BIOLOGY

China’s Rapidly Aging Population Creates Policy Challenges In Shaping A Viable Long-Term Care System

(2013) Zhanlian Feng et al.   HEALTH AFFAIRS

Accelerated neurodegeneration through chaperone-mediated oligomerization of tau

(2013) Laura J. Blair et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH

(2013) Guo Zhang et al.   NATURE

VEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survival

(2013) Piotr Religa et al.   Scientific Reports

oPOSSUM-3: Advanced Analysis of Regulatory Motif Over-Representation Across Genes or ChIP-Seq Datasets

(2013) Andrew T. Kwon et al.   G3-Genes Genomes Genetics

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Gene expression changes with age in skin, adipose tissue, blood and brain

(2013) Daniel Glass et al.   GENOME BIOLOGY

The role of DNA damage and repair in aging through the prism of Koch-like criteria

(2012) Alexey A. Moskalev et al.   AGEING RESEARCH REVIEWS

The transcription factor Sp1 is responsible for aging-dependent altered nucleocytoplasmic trafficking

(2012) Sung Y. Kim et al.   AGING CELL

Aging, Cellular Senescence, and Cancer

(2012) Judith Campisi   Annual Review of Physiology

Identification of novel Sp1 targets involved in proliferation and cancer by functional genomics

(2012) Carlota Oleaga et al.   BIOCHEMICAL PHARMACOLOGY

Hedgehog signalling as an antagonist of ageing and its associated diseases

(2012) Monireh Dashti et al.   BIOESSAYS

AlzPathway: a comprehensive map of signaling pathways of Alzheimer’s disease

(2012) Satoshi Mizuno et al.   BMC Systems Biology

The Critical Role of Metabolic Pathways in Aging

(2012) N. Barzilai et al.   DIABETES

Opportunities in systems biology to discover mechanisms and repurpose drugs for CNS diseases

(2012) Hongkang Mei et al.   DRUG DISCOVERY TODAY

Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice

(2012) Amit Berson et al.   EMBO Molecular Medicine

Nerve growth factor: from the early discoveries to the potential clinical use

(2012) Luigi Aloe et al.   Journal of Translational Medicine

Human Ageing Genomic Resources: Integrated databases and tools for the biology and genetics of ageing

(2012) Robi Tacutu et al.   NUCLEIC ACIDS RESEARCH

Central Role of the EGF Receptor in Neurometabolic Aging

(2012) Sana Siddiqui et al.   International Journal of Endocrinology

Morphological changes in nerve cells during normal aging

(2011) Ennio Pannese   Brain Structure & Function

Temporal dynamics and genetic control of transcription in the human prefrontal cortex

(2011) Carlo Colantuoni et al.   NATURE

Epigenetic Predictor of Age

(2011) Sven Bocklandt et al.   PLoS One

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

(2011) D. R. Green et al.   SCIENCE

A computational evaluation of over-representation of regulatory motifs in the promoter regions of differentially expressed genes

(2010) Guofeng Meng et al.   BMC BIOINFORMATICS

Metabolic Networks of Longevity

(2010) Riekelt H. Houtkooper et al.   CELL

The reproductive-cell cycle theory of aging: An update

(2010) Craig S. Atwood et al.   EXPERIMENTAL GERONTOLOGY

Neural mechanisms of ageing and cognitive decline

(2010) Nicholas A. Bishop et al.   NATURE

Linking functional decline of telomeres, mitochondria and stem cells during ageing

(2010) Ergün Sahin et al.   NATURE

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain

(2010) J. Raphael Gibbs et al.   PLoS Genetics

Biomarkers of aging and disease: Introduction and definitions

(2009) Richard L. Sprott   EXPERIMENTAL GERONTOLOGY

Neuronal death in Alzheimer’s disease and therapeutic opportunities

(2009) Rossen Donev et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

(2008) W. S. Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA