Review
Respiratory System
Haya Jamali, Lauren T. Castillo, Chelsea Cosby Morgan, Jason Coult, Janice L. Muhammad, Oyinkansola O. Osobamiro, Elizabeth C. Parsons, Rosemary Adamson
Summary: The accuracy of pulse oximeters is decreased in patients with dark skin tones, leading to overestimation of oxygen saturation and potential negative clinical outcomes. The degree of inaccuracy varies depending on the pulse oximeter manufacturer, sensor type, and arterial oxygen saturation. Inadequate consideration of melanin's increased absorption of red light during device development and insufficient inclusion of individuals with dark skin tones during device calibration may contribute to the decreased accuracy. Stricter regulatory requirements and increased transparency regarding device performance are needed to address this racial bias.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2022)
Article
Biochemical Research Methods
Neil T. Clancy, Antonio S. Soares, Sophia Bano, Laurence B. Lovat, Manish Chand, Danail Stoyanov
Summary: This study utilizes multispectral imaging laparoscope technology to achieve quantitative measurement of tissue oxygen saturation, demonstrating its potential application in clinical surgeries. The results indicate that this technique can provide surgical guidance by assessing perfusion, helping surgeons in choosing anastomosis points and ensuring the use of well-perfused tissue during surgery.
BIOMEDICAL OPTICS EXPRESS
(2021)
Article
Medicine, General & Internal
Kenta Kawai, Toshiyuki Uchida, Mari Mukai, Masako Matsumoto, Toshiya Itoh, Tomoaki Oda, Yoshimasa Horikoshi, Kazunao Suzuki, Yukiko Kohmura-Kobayashi, Naomi Furuta-Isomura, Chizuko Yaguchi, Masatsugu Niwayama, Hiroaki Itoh, Naohiro Kanayama
Summary: The study evaluated StO(2) levels measured by tissue oximetry in neonates with or without subsequent respiratory disorders diagnosed after an elective cesarean delivery. Lower StO(2) values at 3 and 5 minutes after birth were associated with neonatal respiratory disorders, indicating a potential predisposition for newborns with low StO(2) levels soon after birth.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES
(2021)
Article
Anesthesiology
Fan Cui, Wei Zhao, Dong-Liang Mu, Xu Zhao, Xue-Ying Li, Dong-Xin Wang, Hui-Qun Jia, Feng Dai, Lingzhong Meng
Summary: This study investigated the association between cerebral desaturation and postoperative delirium in thoracic surgical patients undergoing one-lung ventilation (OLV). The results showed that cerebral desaturation defined by <90% baseline for left Scto(2) and <85% baseline for right Scto(2) were associated with an increased risk of delirium, while the minimum Scto(2) and other factors were not significantly associated with delirium.
ANESTHESIA AND ANALGESIA
(2021)
Article
Medicine, General & Internal
Jie Zhang, Haiyan Shen, Huiping Wang, Feng Xiao, Lu Deng, Xiang Chen, Yongqiu Xie
Summary: This study investigated the prevalence and understanding of cerebral oxygen saturation (rSO2) monitoring during anesthesia in geriatric patients among anesthesiologists in China. The results showed a relatively low utilization rate of cerebral oximetry, but the majority of anesthesiologists expressed their willingness to use this technology. The heterogeneity in clinical practice indicated knowledge gaps that should be addressed through further research to optimize treatment.
FRONTIERS IN MEDICINE
(2023)
Article
Veterinary Sciences
Francesca Zanusso, Giulia Maria De Benedictis, Polina Zemko, Luca Bellini
Summary: This study aimed to assess the correlation between the oxygen reserve index (ORi) and partial pressure of oxygen (PaO2), as well as determine its ability to detect mild hyperoxemia in dogs.
BMC VETERINARY RESEARCH
(2023)
Article
Biology
Anouk A. M. A. Lindelauf, Joep A. F. van Rooij, Loes Hartveld, Rene R. W. J. van der Hulst, Patrick W. Weerwind, Rutger M. Schols
Summary: This pilot study investigates the physiological effect of postoperative dangling in lower limb free flap transfer using tissue oximetry. The results showed that tissue oxygen saturation decreased significantly during dangling and improved during the recovery period. Patients with a history of smoking had lower tissue oxygen saturation compared to non-smokers.
Article
Optics
Andrey Tarasov, Denis Lapitan, Dmitry Rogatkin
Summary: Optical non-invasive diagnostic methods and equipment are widely used in various medical disciplines, but there is a lack of a unified engineering theory. Due to limited measured parameters, poorly substantiated technical design parameters, and lack of metrological certification, these devices have limited effectiveness in clinical settings. This study aims to develop a new instrument for non-invasive optical oximetry by creating a more informative tissue oximeter with an enhanced number of measured parameters. It combines two related optical diagnostic techniques on a single hardware platform and applies theoretical modeling for technical design parameter substantiation.
Article
Pediatrics
Ena Suppan, Gerhard Pichler, Corinna Binder-Heschl, Bernhard Schwaberger, Berndt Urlesberger
Summary: Near-infrared spectroscopy (NIRS) measurement of regional cerebral tissue oxygen saturation (rcStO2) in neonatology has attracted great interest. Studies have demonstrated its feasibility in the delivery room and neonatal intensive care unit, and reference ranges for different gestational ages, modes of delivery, and devices have been published. However, interpreting the absolute values and trends of rcStO2 remains challenging, which limits its routine use.
FRONTIERS IN PEDIATRICS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Mark Ooms, Behrus Puladi, Philipp Winnand, Marie Katz, Timm Steiner, Johannes Bickenbach, Frank Holzle, Ali Modabber
Summary: This study aimed to investigate the impact of age on flap perfusion. The results showed that there was no difference in microvascular free flap perfusion between older and younger patients. Age does not affect flap perfusion in radial free forearm flaps, anterolateral thigh flaps, and fibular free flaps.
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY
(2023)
Article
Nursing
Eman Arafa Hassan, Sherouk Nasser Mohamed, Emad Hamdy Hamouda, Nadia Taha Ahmed
Summary: This study found that the pharynx is an accurate site for measuring SpO2 in shocked patients. The results showed that the pharyngeal SpO2 had a bias of less than 0.5% with high precision. Additionally, this method had high sensitivity and specificity in detecting mild and severe hypoxemia.
Review
Chemistry, Analytical
Ana M. Cabanas, Macarena Fuentes-Guajardo, Katina Latorre, Dayneri Leon, Pilar Martin-Escudero
Summary: Pulse oximetry is widely used in primary and intensive care units, especially during the COVID-19 pandemic. However, factors such as skin color can affect its accuracy. Recent studies have found a positive bias in oxygen saturation measurements in patients with darkly pigmented skin. This review aims to assess the influence of skin pigmentation on the accuracy of pulse oximetry through a systematic review.
Article
Anesthesiology
Ilonka N. De Keijzer, Dario Massari, Caren K. Niezen, Reinoud P. H. Bokkers, Jaap Jan Vos, Thomas W. L. Scheeren
Summary: This study validates the use of O3 regional oximetry for monitoring muscle saturation in the quadriceps and flank. However, it is important to note that there is a saturation-level dependent bias and the values obtained at the flank underestimate renal reference values.
JOURNAL OF CLINICAL MONITORING AND COMPUTING
(2023)
Article
Multidisciplinary Sciences
Katharina Raschdorf, Arman Mohseni, Kaavya Hogle, Amanda Cheung, Kitty So, Neda Manouchehri, Mahsa Khalili, Saud Lingawi, Brian Grunau, Calvin Kuo, Jim Christenson, Babak Shadgan
Summary: Sudden cardiac arrest (SCA) is a leading cause of death worldwide, and there is a need for reliable and timely detection methods. We investigated the use of transcutaneous near-infrared spectroscopy (NIRS) to detect changes during cardiac arrest. Our study found that NIRS monitoring can identify rapid hemodynamic changes in a similar timeframe to invasive measurements.
SCIENTIFIC REPORTS
(2023)
Article
Engineering, Electrical & Electronic
Meltem Izzetoglu, Kambiz Pourrezaei, Juan Du, Patricia A. Shewokis
Summary: The study evaluated the performance of multiple commercially available CTO devices using realistic and dynamic multilayer mixed solid and liquid phantom design with controlled and repeatable test procedures. Results indicated that the CTO devices were very precise and highly correlated, but showed varying levels of accuracy, sensitivity, static, and proportional bias under continuously changing oxygen saturation conditions. The Gauge R&R analysis showed that most CTO devices were within acceptable ranges with good precision and reproducibility.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2021)