Journal
PLASMA PROCESSES AND POLYMERS
Volume 13, Issue 6, Pages 588-597Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ppap.201600010
Keywords
bacterial inactivation; fungal inactivation; non-thermal plasmas; onychomycosis
Funding
- National Science Foundation [IIP 1343994]
- National Science Foundation under SBIR program [03603]
- Department of Energy [DE-SC0008380, DE-SC0012500]
- Office of Fusion Energy Science Plasma Science Center
- U.S. Department of Energy (DOE) [DE-SC0008380, DE-SC0012500] Funding Source: U.S. Department of Energy (DOE)
- Directorate For Engineering
- Div Of Industrial Innovation & Partnersh [1533478] Funding Source: National Science Foundation
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We report on the use of three cold atmospheric plasma (CAP) devices in treating model nails that have been coated on the backside of the nail with either Escherichia coli (E. coli) bacteria or Trichophyton rubrum (T. rubrum) fungus. We tested a helium plasma jet; a surface microdischarge plasma device; and a floating electrode dielectric barrier discharge. All of the devices, acting through the model nail, showed significant log reductions of bacterial and fungal targets in several tens of minutes. CAP technology appears to offer promise as a safe, effective, and inexpensive therapy for fungal nail infection treatment.
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