Production of dengue virus envelope protein domain III-based antigens in tobacco chloroplasts using inducible and constitutive expression systems

Cooperation between the chloroplastpsbA5′-untranslated region and coding region is important for translational initiation: the chloroplast translation machinery cannot read a human viral gene coding region

(2016) Masayuki Nakamura et al.   PLANT JOURNAL

Transplastomic plants for innovations in agriculture. A review

(2015) Shabir Hussain Wani et al.   Agronomy for Sustainable Development

Engineering Plastid Genomes: Methods, Tools, and Applications in Basic Research and Biotechnology

(2015) Ralph Bock   Annual Review of Plant Biology

High-value products from plants: the challenges of process optimization

(2015) Rainer Fischer et al.   CURRENT OPINION IN BIOTECHNOLOGY

Dengue vaccines: Challenges, development, current status and prospects

(2015) L Dar et al.   Indian Journal of Medical Microbiology

Expression and characterization of an M cell-specific ligand-fused dengue virus tetravalent epitope using Saccharomyces cerevisiae

(2015) Ngoc-Luong Nguyen et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Preventing Dengue — Is the Possibility Now a Reality?

(2015) Stephen J. Thomas   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic Disease

(2015) Sri Rezeki Hadinegoro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy of a Tetravalent Dengue Vaccine in Children in Latin America

(2015) Luis Villar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Boosting riboswitch efficiency by RNA amplification

(2015) Masoumeh Emadpour et al.   NUCLEIC ACIDS RESEARCH

Phaseolin expression in tobacco chloroplast reveals an autoregulatory mechanism in heterologous protein translation

(2015) Francesca De Marchis et al.   PLANT BIOTECHNOLOGY JOURNAL

A mutant Synechococcus gene encoding glutamate 1-semialdehyde aminotransferase confers gabaculine resistance when expressed in tobacco plastids

(2015) Michele Bellucci et al.   PLANT CELL REPORTS

Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial

(2014) Maria Rosario Capeding et al.   LANCET

Induction of Neutralizing Antibodies against Four Serotypes of Dengue Viruses by MixBiEDIII, a Tetravalent Dengue Vaccine

(2014) Hui Zhao et al.   PLoS One

The HIV-1 Pr55gag polyprotein binds to plastidial membranes and leads to severe impairment of chloroplast biogenesis and seedling lethality in transplastomic tobacco plants

(2014) N. Scotti et al.   TRANSGENIC RESEARCH

Manufacturing Economics of Plant-Made Biologics: Case Studies in Therapeutic and Industrial Enzymes

(2014) Daniel Tusé et al.   Biomed Research International

Transgene-induced pleiotropic effects in transplastomic plants

(2013) N. Scotti et al.   BIOTECHNOLOGY LETTERS

Genetic engineering of the chloroplast: novel tools and new applications

(2013) Ralph Bock   CURRENT OPINION IN BIOTECHNOLOGY

Commercial Aspects of Pharmaceutical Protein Production in Plants

(2013) Rainer Fischer et al.   CURRENT PHARMACEUTICAL DESIGN

Plant biotechnology for food security and bioeconomy

(2013) Jihong Liu Clarke et al.   PLANT MOLECULAR BIOLOGY

pAUL: A Gateway-Based Vector System for Adaptive Expression and Flexible Tagging of Proteins in Arabidopsis

(2013) Dagmar Lyska et al.   PLoS One

Efficient metabolic pathway engineering in transgenic tobacco and tomato plastids with synthetic multigene operons

(2013) Y. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dengue-1 envelope protein domain III produced in Pichia pastoris: Potential use for serological diagnosis

(2013) Silvia A. Cardoso et al.   PROTEIN EXPRESSION AND PURIFICATION

A novel chloroplast transformation vector compatible with the Gateway® recombination cloning technology

(2013) Johanna Gottschamel et al.   TRANSGENIC RESEARCH

The Economic Burden of Dengue

(2012) Duane J. Gubler   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

M Cell-Targeting Ligand and Consensus Dengue Virus Envelope Protein Domain III Fusion Protein Production in Transgenic Rice Calli

(2012) Tae-Geum Kim et al.   MOLECULAR BIOTECHNOLOGY

Plastid Proteostasis and Heterologous Protein Accumulation in Transplastomic Plants

(2012) F. De Marchis et al.   PLANT PHYSIOLOGY

Delivery of multiple transgenes to plant cells by an improved version of MultiRound Gateway technology

(2012) Matthias Buntru et al.   TRANSGENIC RESEARCH

Gateway vectors for transformation of cereals

(2012) Mansour Karimi et al.   TRENDS IN PLANT SCIENCE

Virus-like particles displaying envelope domain III of dengue virus type 2 induce virus-specific antibody response in mice

(2012) Upasana Arora et al.   VACCINE

GMP issues for recombinant plant-derived pharmaceutical proteins

(2011) Rainer Fischer et al.   BIOTECHNOLOGY ADVANCES

Recombinant dengue virus type 3 envelope domain III protein from Escherichia coli

(2011) Nagesh K. Tripathi et al.   Biotechnology Journal

Clinical development of plant-produced recombinant pharmaceuticals: Vaccines, antibodies and beyond

(2011) Vidadi Yusibov et al.   Human vaccines & immunotherapeutics

Plastid expression of a double-pentameric vaccine candidate containing human papillomavirus-16 L1 antigen fused with LTB as adjuvant: transplastomic plants show pleiotropic phenotypes

(2011) Mohammad T. Waheed et al.   PLANT BIOTECHNOLOGY JOURNAL

Chloroplast-derived vaccines against human diseases: achievements, challenges and scopes

(2011) Andreas G. Lössl et al.   PLANT BIOTECHNOLOGY JOURNAL

High-level expression of a suite of thermostable cell wall-degrading enzymes from the chloroplast genome

(2011) Kerstin Petersen et al.   PLANT MOLECULAR BIOLOGY

Plastid biotechnology for crop production: present status and future perspectives

(2011) Jihong Liu Clarke et al.   PLANT MOLECULAR BIOLOGY

Expression of dengue-3 premembrane and envelope polyprotein in lettuce chloroplasts

(2011) Anderson Paul Kanagaraj et al.   PLANT MOLECULAR BIOLOGY

Plastid Biotechnology: Food, Fuel, and Medicine for the 21st Century

(2011) P. Maliga et al.   PLANT PHYSIOLOGY

From research to phase III: Preclinical, industrial and clinical development of the Sanofi Pasteur tetravalent dengue vaccine

(2011) Bruno Guy et al.   VACCINE

Exploring different strategies to express Dengue virus envelope protein in a plant system

(2010) Carolina Andrea Martínez et al.   BIOTECHNOLOGY LETTERS

Domain III of the envelope protein as a dengue vaccine target

(2010) Maria G Guzman et al.   Expert Review of Vaccines

Pichia pastoris-expressed dengue virus type 2 envelope domain III elicits virus-neutralizing antibodies

(2010) Gaurav Batra et al.   JOURNAL OF VIROLOGICAL METHODS

Identification of protein stability determinants in chloroplasts

(2010) Wiebke Apel et al.   PLANT JOURNAL

Inducible gene expression from the plastid genome by a synthetic riboswitch

(2010) A. Verhounig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression, purification and characterization of in vivo biotinylated dengue virus envelope domain III based tetravalent antigen

(2010) Gaurav Batra et al.   PROTEIN EXPRESSION AND PURIFICATION

Solar-powered factories for new vaccines and antibiotics

(2010) Ralph Bock et al.   TRENDS IN BIOTECHNOLOGY

Development of a recombinant tetravalent dengue virus vaccine: Immunogenicity and efficacy studies in mice and monkeys

(2010) David E. Clements et al.   VACCINE

Molecular evolution of dengue viruses: Contributions of phylogenetics to understanding the history and epidemiology of the preeminent arboviral disease

(2009) Scott C. Weaver et al.   INFECTION GENETICS AND EVOLUTION

Plant Physiological Adaptations to the Massive Foreign Protein Synthesis Occurring in Recombinant Chloroplasts

(2009) J. Bally et al.   PLANT PHYSIOLOGY

Plastid production of protein antibiotics against pneumonia via a new strategy for high-level expression of antimicrobial proteins

(2009) M. Oey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dengue and dengue haemorrhagic fever: Indian perspective

(2008) U. C. Chaturvedi et al.   JOURNAL OF BIOSCIENCES

Production and characterization of recombinant dengue virus type 4 envelope domain III protein

(2008) N TRIPATHI et al.   JOURNAL OF BIOTECHNOLOGY

High-level expression of human immunodeficiency virus antigens from the tobacco and tomato plastid genomes

(2008) Fei Zhou et al.   PLANT BIOTECHNOLOGY JOURNAL

Translocation of aprotinin, a therapeutic protease inhibitor, into the thylakoid lumen of genetically engineered tobacco chloroplasts

(2008) Ghislaine Tissot et al.   PLANT BIOTECHNOLOGY JOURNAL

Plastid Transcriptomics and Translatomics of Tomato Fruit Development and Chloroplast-to-Chromoplast Differentiation: Chromoplast Gene Expression Largely Serves the Production of a Single Protein

(2008) S. Kahlau et al.   PLANT CELL

Exhaustion of the chloroplast protein synthesis capacity by massive expression of a highly stable protein antibiotic

(2008) Melanie Oey et al.   PLANT JOURNAL

A modified Gateway cloning strategy for overexpressing tagged proteins in plants

(2008) Manu J Dubin et al.   Plant Methods