Article
Pharmacology & Pharmacy
Lei Zhao, Lei Wang, Zimeng Guo, Ning Zhang, Qisheng Feng, Bo Li
Summary: Two polysaccharide fractions (PCB-1 and PCB2-1) were isolated from Pogostemon cablin and were found to possess significant antioxidant activities. In vitro experiments showed that the polysaccharides exhibited high scavenging activity against hydroxyl radicals and metal ion-chelating abilities. In vivo experiments in a mice model also demonstrated the potential of PCB-1 as an antioxidant by increasing the levels of antioxidant enzymes and inhibiting malondialdehyde formation.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Xingjia Peng, Song Ang, Yizi Zhang, Fenling Fan, Mengshuo Wu, Peiting Liang, Yan Wen, Lishe Gan, Kun Zhang, Dongli Li, Jianmin Yue
Summary: Several compounds with anti-cancer effects were isolated from Pogostemon cablin, with compound 19 showing significant induction of apoptosis in HepG2 cells.
FRONTIERS IN CHEMISTRY
(2022)
Review
Integrative & Complementary Medicine
Chen Junren, Xie Xiaofang, Li Mengting, Xiong Qiuyun, Li Gangmin, Zhang Huiqiong, Chen Guanru, Xu Xin, Yin Yanpeng, Peng Fu, Peng Cheng
Summary: Patchouli, or Pogostemon cablin Benth, is a traditional Chinese medicinal herb known for its therapeutic effects on colds, nausea, fever, and headache. It contains various bioactive compounds with pharmacological impacts such as anti-microbial, anti-oxidative, anti-inflammatory, and analgesic effects. Studies have shown recent progress in phytochemistry and pharmacology of patchouli, providing a basis for future research on its clinical applications.
Article
Agricultural Engineering
Shubham Srivastava, R. K. Lal, V. R. Singh, P. K. Rout, R. C. Padalia, Anju Kumari Yadav, Laldingngheti Bawitlung, Divya Bhatt, Anil K. Maurya, A. Pal, D. U. Bawankule, Anand Mishra, P. Gupta, C. S. Chanotiya
Summary: Pogostemon cablin (Blanco) Benth. plant is known for its high essential oil production, and a new variety has been developed for cultivation in India. The patchouli essential oil exhibits significant anti-inflammatory and antimicrobial activities. Various sesquiterpenoids with these activities have been identified. In addition, a new method for authenticating patchouli essential oils has been reported.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Pharmacology & Pharmacy
Yizhe Cui, Qiuju Wang, Renxu Chang, Ahmad Aboragah, Juan J. Loor, Chuang Xu
Summary: The study found that Pogostemon cablin can prevent and treat nonalcoholic fatty liver disease through various pathways and targets, including regulating lipid metabolism, anti-inflammatory, and antioxidant pathways. Pharmacological experiments demonstrated that Pogostemon cablin can reduce lipid accumulation and improve liver inflammation by inhibiting the activation of NF-kappa B/I kappa B signaling and decreasing the release of pro-inflammatory factors.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Agricultural Engineering
R. K. Lal, C. S. Chanotiya, V. R. Singh, A. Kumar
Summary: Patchouli essential oil is an excellent fixative for strong perfumes, adding strength, character, seductive notes, and enduring properties. Its cultivation and production can provide crucial information about growth patterns and compatibility with different environmental conditions. Patchouli is gaining popularity due to its simplicity in cultivation, especially in shady orchards or forests. The study identified stable patchouli lines with high essential oil yields and distinctive aromas.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Plant Sciences
Zafar I. Warsi, Kahkashan Khatoon, Pooja Singh, Laiq Ur Rahman
Summary: The cultivation of Pogostemon cablin faces challenges due to its susceptibility to drought stress, which reduces propagation and oil yield. This study successfully established an efficient direct regeneration system for transgenic production of P. cablin using Agrobacterium-mediated genetic transformation. Leaf segments showed the highest regeneration frequency of 93.30% on optimal MS medium fortified with 0.2mg/L BAP and 0.1mg/L NAA, with a faster regeneration time compared to other explants.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Horticulture
Le Thi Diem, Truong Hoai Phong, Hoang Thanh Tung, Hoang Dac Khai, Truong Thi Lan Anh, Nguyen Thi Nhu Mai, Do Manh Cuong, Vu Quoc Luan, Tran Que, Hoang Thi Nhu Phuong, Bui Van The Vinh, Duong Tan Nhut
Summary: In this study, a protocol for polyploid induction of Ngoc Linh ginseng was developed using silver nanoparticles for disinfection and colchicine treatment for embryo induction. Tetraploid Ngoc Linh ginseng plants with larger stomatal size, higher stomatal chloroplast density, and better growth were successfully induced.
SCIENTIA HORTICULTURAE
(2022)
Article
Multidisciplinary Sciences
Hongyi Zhang, Wenjing Deng, Changhua Lu, Mengling He, Hanjing Yan
Summary: In this study, the researchers constructed de novo transcriptomes from two chemical types of Pogostemon cablin using the Pacific Biosciences Sequel platform and performed differential expression analysis. They found genetic differences between the two types that contribute to differences in morphology and biosynthetic capabilities. The study identified key pathways involved in the biosynthesis of secondary metabolites and provided important insights for further genome annotation and transcriptome research in P. cablin.
Review
Biochemistry & Molecular Biology
Sehrish Fatima, Iqra Farzeen, Asma Ashraf, Bilal Aslam, Muhammad Umar Ijaz, Sumreen Hayat, Muhammad Hassan Sarfraz, Saima Zafar, Nimrah Zafar, Jeremiah Oshiomame Unuofin, Sogolo Lucky Lebelo, Saima Muzammil
Summary: Plant products have gained increasing importance in the pharmaceutical industry. Pogostemon Cablin, commonly known as patchouli, is a widely used herb in the fragrance industries, and it offers various therapeutic benefits. Patchouli oil has been traditionally used for its flavoring properties and is recognized by the FDA. It has seen a surge in use in recent years, with Indonesia being the largest producer. The oil has diverse applications, from traditional therapies for colds and fevers to aromatherapy for stress relief and enhancing sexual attraction.
Article
Chemistry, Analytical
Bin Xie, Xue-Feng Wu, Hui-Tai Luo, Xiao-Lan Huang, Fang Huang, Qiu-Yan Zhang, Xi Zhou, Hui-Qin Wu
Summary: This study identified and characterized 73 non-volatile constituents of Pogostemon cablin Benth using HPLC-Q-TOF-MS, and classified the samples into herbal decoction pieces and processed medicinal materials. Potential chemical markers were screened to distinguish the two groups, providing valuable information for further quality evaluation of PCB.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Plant Sciences
Yanfen Gao, Junchao Ma, Jiaqi Chen, Qian Xu, Yanxia Jia, Hongying Chen, Weiqi Li, Liang Lin
Summary: This study successfully established a novel method for establishing homogeneous tetraploid embryogenic cell lines in Magnolia officinalis, maximizing the production of solid polyploids through regenerants of single cell origin, and confirming the stability of ploidy level through flow cytometry and chromosome counting.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Chemistry, Medicinal
Puji Astuti, Khairan Khairan, Marthoenis Marthoenis, Kartini Hasballah
Summary: This study investigated the antidepressant potential of patchouli oil containing high concentrations of patchouli alcohol, obtained through vacuum distillation with different temperature ranges. Results showed that the oil with the highest patchouli alcohol content had significant antidepressant effects in a rat model, possibly through increased brain dopamine levels.
Article
Plant Sciences
Jianrong Zeng, Chengmei Li, Jianzhong Liu, Yingying Li, Zhenzhen Hu, Mengling He, Hongyi Zhang, Hanjing Yan
Summary: Researchers utilized geographic records and environmental variables to determine key environmental parameters for P. cablin cultivation, identifying southwestern Guangdong, a portion of central Guangdong, and southern Hainan as most suitable for cultivation; future regions for artificial P. cablin cultivation will also be accessible.
JOURNAL OF APPLIED RESEARCH ON MEDICINAL AND AROMATIC PLANTS
(2021)
Article
Biochemistry & Molecular Biology
Khairan Khairan, Miftahul Hasan, Rinaldi Idroes, Muhammad Diah
Summary: Research was conducted on the manufacture of hydrogel films using polyvinyl alcohol, corn starch, patchouli oil, and silver nanoparticles. The silver nanoparticles were synthesized using green synthesis methods from patchouli plants. The resulting hydrogel films showed flexibility, no holes or air bubbles, and were slightly agglomerated. The hydrogel films exhibited thermal stability and antibacterial activity against Staphylococcus aureus and Staphylococcus epidermis, with the best activity observed in the hydrogel film loaded with silver nanoparticles synthesized in aqueous of patchouli leaf extract and light fraction of patchouli oil.
