CAX-ing a wide net: Cation/H+ transporters in metal remediation and abiotic stress signalling

On the move, lysosomal CAX drives Ca2+transport and motility

(2016) Emyr Lloyd-Evans   JOURNAL OF CELL BIOLOGY

Ca2+/H+exchange by acidic organelles regulates cell migration in vivo

(2016) Manuela Melchionda et al.   JOURNAL OF CELL BIOLOGY

Tissue-specific root ion profiling reveals essential roles of the CAX and ACA calcium transport systems in response to hypoxia in Arabidopsis

(2016) Feifei Wang et al.   JOURNAL OF EXPERIMENTAL BOTANY

Regulation of mitochondrial calcium in plants versus animals

(2016) Stephan Wagner et al.   JOURNAL OF EXPERIMENTAL BOTANY

Phylogenetic analysis and protein structure modelling identifies distinct Ca2+/Cation antiporters and conservation of gene family structure within Arabidopsis and rice species

(2016) Jon K. Pittman et al.   Rice

Functional analysis of CAX2-like transporters isolated from two ecotypes of Sedum alfredii

(2015) M. Zhang et al.   BIOLOGIA PLANTARUM

Vcx1 and ESCRT components regulate intracellular pH homeostasis in the response of yeast cells to calcium stress

(2015) Klara Papouskova et al.   FEMS YEAST RESEARCH

Combining modelling and experimental approaches to explain how calcium signatures are decoded by calmodulin-binding transcription activators (CAMTAs) to produce specific gene expression responses

(2015) Junli Liu et al.   NEW PHYTOLOGIST

pH Regulation by NHX-Type Antiporters Is Required for Receptor-Mediated Protein Trafficking to the Vacuole in Arabidopsis

(2015) Maria Reguera et al.   PLANT CELL

Ca2+-regulated and diurnal rhythm-regulated Na+/Ca2+exchanger AtNCL affects flowering time and auxin signalling inArabidopsis

(2015) Penghui Li et al.   PLANT CELL AND ENVIRONMENT

CATION EXCHANGER1Cosegregates with Cadmium Tolerance in the Metal HyperaccumulatorArabidopsis halleriand Plays a Role in Limiting Oxidative Stress inArabidopsisSpp.

(2015) Cecilia Baliardini et al.   PLANT PHYSIOLOGY

Vacuoles protect plants from high magnesium stress: Fig. 1.

(2015) Caiji Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium signaling mediates the response to cadmium toxicity inSaccharomyces cerevisiaecells

(2014) Lavinia L. Ruta et al.   FEBS LETTERS

Life and death under salt stress: same players, different timing?

(2014) Ahmed Ismail et al.   JOURNAL OF EXPERIMENTAL BOTANY

Genetical and Comparative Genomics ofBrassicaunder Altered Ca Supply IdentifiesArabidopsisCa-Transporter Orthologs

(2014) Neil S. Graham et al.   PLANT CELL

Expression and functional analysis of putative vacuolar Ca2+-transporters (CAXs and ACAs) in roots of salt tolerant and sensitive rice cultivars

(2014) Nana Yamada et al.   PROTOPLASMA

Mn-euvering manganese: the role of transporter gene family members in manganese uptake and mobilization in plants

(2014) Amanda L. Socha et al.   Frontiers in Plant Science

Calcium partitioning and allocation and blossom-end rot development in tomato plants in response to whole-plant and fruit-specific abscisic acid treatments

(2013) Sergio Tonetto de Freitas et al.   JOURNAL OF EXPERIMENTAL BOTANY

Structural basis for alternating access of a eukaryotic calcium/proton exchanger

(2013) Andrew B. Waight et al.   NATURE

Boron deficiency increases the levels of cytosolic Ca2+ and expression of Ca2+-related genes in Arabidopsis thaliana roots

(2013) Carlos Quiles-Pando et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Is Ca2+ involved in the signal transduction pathway of boron deficiency? New hypotheses for sensing boron deprivation

(2013) Agustín González-Fontes et al.   PLANT SCIENCE

GhCAX3 Gene, a Novel Ca2+/H+ Exchanger from Cotton, Confers Regulation of Cold Response and ABA Induced Signal Transduction

(2013) Lian Xu et al.   PLoS One

Crystal structure of Ca2+/H+ antiporter protein YfkE reveals the mechanisms of Ca2+ efflux and its pH regulation

(2013) M. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for the Counter-Transport Mechanism of a H+/Ca2+ Exchanger

(2013) T. Nishizawa et al.   SCIENCE

The Plasmodium berghei Ca2+/H+ Exchanger, PbCAX, Is Essential for Tolerance to Environmental Ca2+ during Sexual Development

(2013) David S. Guttery et al.   PLoS Pathogens

A Na+/Ca2+Exchanger-like Protein (AtNCL) Involved in Salt Stress inArabidopsis

(2012) Peng Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

(2012) Christine Vogel et al.   NATURE REVIEWS GENETICS

Calcium signatures are decoded by plants to give specific gene responses

(2012) Helen J. Whalley et al.   NEW PHYTOLOGIST

In Silico Analysis of Expression Data for Identification of Genes Involved in Spatial Accumulation of Calcium in Developing Seeds of Rice

(2012) Anshita Goel et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Vacuolar CAX1 and CAX3 Influence Auxin Transport in Guard Cells via Regulation of Apoplastic pH

(2012) D. Cho et al.   PLANT PHYSIOLOGY

Knockout of Multiple Arabidopsis Cation/H+ Exchangers Suggests Isoform-Specific Roles in Metal Stress Response, Germination and Seed Mineral Nutrition

(2012) James M. Connorton et al.   PLoS One

Plant Calcium Content: Ready to Remodel

(2012) Jian Yang et al.   Nutrients

Protein Phylogenetic Analysis of Ca2+/cation Antiporters and Insights into their Evolution in Plants

(2012) Laura Emery et al.   Frontiers in Plant Science

Multiple Transport Pathways for Mediating Intracellular pH Homeostasis: The Contribution of H+/ion Exchangers

(2012) Jon K. Pittman   Frontiers in Plant Science

Characterization ofArabidopsisCa2+/H+Exchanger CAX3

(2011) Murli Manohar et al.   BIOCHEMISTRY

Vacuolar Ca2+ uptake

(2011) Jon K. Pittman   CELL CALCIUM

Comparative study of the active cadmium efflux systems operating at the plasma membrane and tonoplast of cucumber root cells

(2011) M. Migocka et al.   JOURNAL OF EXPERIMENTAL BOTANY

Exploiting natural variation to uncover candidate genes that control element accumulation in Arabidopsis thaliana

(2011) Simon J. Conn et al.   NEW PHYTOLOGIST

Plant cation/H+ exchangers (CAXs): biological functions and genetic manipulations

(2011) M. Manohar et al.   PLANT BIOLOGY

Cell-Specific Vacuolar Calcium Storage Mediated byCAX1Regulates Apoplastic Calcium Concentration, Gas Exchange, and Plant Productivity inArabidopsis

(2011) Simon J. Conn et al.   PLANT CELL

Expression of a Suaeda salsa Vacuolar H+/Ca2+ Transporter Gene in Arabidopsis Contributes to Physiological Changes in Salinity

(2011) Ning Han et al.   PLANT MOLECULAR BIOLOGY REPORTER

Vacuolar Ca2+/H+ Transport Activity Is Required for Systemic Phosphate Homeostasis Involving Shoot-to-Root Signaling in Arabidopsis

(2011) T.-Y. Liu et al.   PLANT PHYSIOLOGY

The Role of CAX1 and CAX3 in Elemental Distribution and Abundance in Arabidopsis Seed

(2011) T. Punshon et al.   PLANT PHYSIOLOGY

Zebrafish (Danio rerio) Endomembrane Antiporter Similar to a Yeast Cation/H+Transporter Is Required for Neural Crest Development

(2010) Murli Manohar et al.   BIOCHEMISTRY

Cadmium exposure in the population: from health risks to strategies of prevention

(2010) Tim S. Nawrot et al.   BIOMETALS

Expression of an Arabidopsis Ca2+/H+ antiporter CAX1 variant in petunia enhances cadmium tolerance and accumulation

(2010) Qingyu Wu et al.   JOURNAL OF PLANT PHYSIOLOGY

PfCHA is a mitochondrial divalent cation/H+ antiporter in Plasmodium falciparum

(2010) Alexander Rotmann et al.   MOLECULAR MICROBIOLOGY

Using synchrotron X-ray fluorescence microprobes in the study of metal homeostasis in plants

(2009) Tracy Punshon et al.   ANNALS OF BOTANY

Functional Studies of Split Arabidopsis Ca2+/H+Exchangers

(2009) Jian Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Improved watermelon quality using bottle gourd rootstock expressing a Ca2+/H+ antiporter

(2009) Jeung-Sul Han et al.   MOLECULAR BREEDING

Root development under metal stress inArabidopsis thalianarequires the H+/cation antiporter CAX4

(2009) Hui Mei et al.   NEW PHYTOLOGIST

Root-selective expression ofAtCAX4andAtCAX2results in reduced lamina cadmium in field-grownNicotiana tabacumL.

(2009) Victor Korenkov et al.   PLANT BIOTECHNOLOGY JOURNAL

NCLX is an essential component of mitochondrial Na+/Ca2+ exchange

(2009) R. Palty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative detection of changes in the leaf-mesophyll tonoplast proteome in dependency of a cadmium exposure of barley (Hordeum vulgare L.) plants

(2009) Thomas Schneider et al.   PROTEOMICS

Comparative analysis of CAX2-like cation transporters indicates functional and regulatory diversity

(2008) Clare Edmond et al.   BIOCHEMICAL JOURNAL

Interaction betweenArabidopsisCa2+/H+Exchangers CAX1 and CAX3

(2008) Jian Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Cation-regulated and Proton Gradient-dependent Cation Transporter fromChlamydomonas reinhardtiiHas a Role in Calcium and Sodium Homeostasis

(2008) Jon K. Pittman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shaping the calcium signature

(2008) Martin R. McAinsh et al.   NEW PHYTOLOGIST

Sensory analysis of calcium-biofortified lettuce

(2008) Sunghun Park et al.   PLANT BIOTECHNOLOGY JOURNAL

Nutritional impact of elevated calcium transport activity in carrots

(2008) J. Morris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nutritional improvements in plants: time to bite on biofortified foods

(2008) Kendal Hirschi   TRENDS IN PLANT SCIENCE