Bidirectional cross talk between patient-derived melanoma and cancer-associated fibroblasts promotes invasion and proliferation

Melanoma Cells Block PEDF Production in Fibroblasts to Induce the Tumor-Promoting Phenotype of Cancer-Associated Fibroblasts

(2016) Nkechiyere G. Nwani et al.   CANCER RESEARCH

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Intravital Imaging Reveals How BRAF Inhibition Generates Drug-Tolerant Microenvironments with High Integrin β1/FAK Signaling

(2015) Eishu Hirata et al.   CANCER CELL

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

(2015) Alexandre Calon et al.   NATURE GENETICS

Stromal contribution to the colorectal cancer transcriptome

(2015) Claudio Isella et al.   NATURE GENETICS

Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines

(2015) Ikrame Lazar et al.   Pigment Cell & Melanoma Research

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression

(2014) G Denecker et al.   CELL DEATH AND DIFFERENTIATION

Senescent stroma promotes prostate cancer progression: The role of miR-210

(2014) Maria Letizia Taddei et al.   Molecular Oncology

Regulation of the anti-tumour immune response by cancer-associated fibroblasts

(2014) James Harper et al.   SEMINARS IN CANCER BIOLOGY

Melanoma Cells Revive an Embryonic Transcriptional Network to Dictate Phenotypic Heterogeneity

(2014) Niels Vandamme et al.   Frontiers in Oncology

Stromal fibroblasts in the microenvironment of gastric carcinomas promote tumor metastasis via upregulating TAGLN expression

(2013) Beiqin Yu et al.   BMC CELL BIOLOGY

A Switch in the Expression of Embryonic EMT-Inducers Drives the Development of Malignant Melanoma

(2013) Julie Caramel et al.   CANCER CELL

Senescent Fibroblasts in Melanoma Initiation and Progression: An Integrated Theoretical, Experimental, and Clinical Approach

(2013) E. Kim et al.   CANCER RESEARCH

Carcinoma-associated fibroblasts: Non-neoplastic tumour-promoting mesenchymal cells

(2013) Urszula M. Polanska et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer

(2013) C. Feig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Epidermal Growth Factor Receptor in Cancer Metastasis and Microenvironment

(2013) Takamitsu Sasaki et al.   Biomed Research International

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

(2012) Alexandre Calon et al.   CANCER CELL

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non-Small Cell Lung Cancer In Vivo

(2012) S. Vicent et al.   CANCER RESEARCH

MDA-9/Syntenin and IGFBP-2 Promote Angiogenesis in Human Melanoma

(2012) S. K. Das et al.   CANCER RESEARCH

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

(2012) Ravid Straussman et al.   NATURE

Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B

(2012) Yu Sun et al.   NATURE MEDICINE

Cadherin-23 Mediates Heterotypic Cell-Cell Adhesion between Breast Cancer Epithelial Cells and Fibroblasts

(2012) Maria Apostolopoulou et al.   PLoS One

Origins of the Tumor Microenvironment: Quantitative Assessment of Adipose-Derived and Bone Marrow–Derived Stroma

(2012) Shannon Kidd et al.   PLoS One

Cancer Associated Fibroblasts Exploit Reactive Oxygen Species Through a Proinflammatory Signature Leading to Epithelial Mesenchymal Transition and Stemness

(2011) Elisa Giannoni et al.   ANTIOXIDANTS & REDOX SIGNALING

Plasma Markers for Identifying Patients with Metastatic Melanoma

(2011) H. M. Kluger et al.   CLINICAL CANCER RESEARCH

Cancer-associated fibroblasts correlate with poor prognosis in rectal cancer after chemoradiotherapy

(2011) Saigusa   INTERNATIONAL JOURNAL OF ONCOLOGY

Melanoma Cells Control HA Synthesis in Peritumoral Fibroblasts via PDGF-AA and PDGF-CC: Impact on Melanoma Cell Proliferation

(2011) Anja Willenberg et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer

(2011) R. Navab et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

iRefWeb: interactive analysis of consolidated protein interaction data and their supporting evidence

(2011) B. Turner et al.   Database-The Journal of Biological Databases and Curation

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Matrix Metalloproteinases Contribute Distinct Roles in Neuroendocrine Prostate Carcinogenesis, Metastasis, and Angiogenesis Progression

(2010) L. E. Littlepage et al.   CANCER RESEARCH

Hallmarks of cancer: Interactions with the tumor stroma

(2010) Kristian Pietras et al.   EXPERIMENTAL CELL RESEARCH

Autocrine TGF-  and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

(2010) Y. Kojima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-Associated Fibroblasts as “Trojan Horse” Mediators of Resistance to Anti-VEGF Therapy

(2009) Giulio Francia et al.   CANCER CELL

PDGF-C Mediates the Angiogenic and Tumorigenic Properties of Fibroblasts Associated with Tumors Refractory to Anti-VEGF Treatment

(2009) Yongping Crawford et al.   CANCER CELL

Cancer associated fibroblasts (CAFs) in tumor microenvironment

(2009) Fei Xing   Frontiers in Bioscience-Landmark

Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast

(2009) M. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Modification of the Primary Tumor Microenvironment by Transforming Growth Factor α-Epidermal Growth Factor Receptor Signaling Promotes Metastasis in an Orthotopic Colon Cancer Model

(2008) Takamitsu Sasaki et al.   AMERICAN JOURNAL OF PATHOLOGY

The role of endothelial-to-mesenchymal transition in cancer progression

(2008) S Potenta et al.   BRITISH JOURNAL OF CANCER

Stromal Transforming Growth Factor-  Signaling Mediates Prostatic Response to Androgen Ablation by Paracrine Wnt Activity

(2008) V. R. Placencio et al.   CANCER RESEARCH

Carcinoma-Associated Fibroblast-Like Differentiation of Human Mesenchymal Stem Cells

(2008) P. J. Mishra et al.   CANCER RESEARCH

Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression

(2008) R. F. Hwang et al.   CANCER RESEARCH

Stromal Fibroblasts Activated by Tumor Cells Promote Angiogenesis in Mouse Gastric Cancer

(2008) Xiaoying Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of novel epigenetically modified genes in human melanoma via promoter methylation gene profiling

(2008) Suhu Liu et al.   Pigment Cell & Melanoma Research

Melanoma and the tumor microenvironment

(2008) Jessie Villanueva et al.   Current Oncology Reports