Amylin–Aβ oligomers at atomic resolution using molecular dynamics simulations: a link between Type 2 diabetes and Alzheimer's disease

In Vivo Seeding and Cross-Seeding of Localized Amyloidosis

(2015) Marie E. Oskarsson et al.   AMERICAN JOURNAL OF PATHOLOGY

Insights into the consequences of co-polymerisation in the early stages of IAPP and Aβ peptide assembly from mass spectrometry

(2015) Lydia M. Young et al.   ANALYST

Alzheimer’s Protective A2T Mutation Changes the Conformational Landscape of the Aβ1–42 Monomer Differently Than Does the A2V Mutation

(2015) Payel Das et al.   BIOPHYSICAL JOURNAL

Amyloid β Protein and Alzheimer’s Disease: When Computer Simulations Complement Experimental Studies

(2015) Jessica Nasica-Labouze et al.   CHEMICAL REVIEWS

Coupling of Zinc-Binding and Secondary Structure in Nonfibrillar Aβ40 Peptide Oligomerization

(2015) Liang Xu et al.   Journal of Chemical Information and Modeling

Probing the Sources of the Apparent Irreproducibility of Amyloid Formation: Drastic Changes in Kinetics and a Switch in Mechanism Due to Micellelike Oligomer Formation at Critical Concentrations of IAPP

(2015) Jeffrey R. Brender et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

(2015) Yiling Xiao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

(2015) Yiling Xiao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

High-resolution NMR characterization of low abundance oligomers of amyloid-β without purification

(2015) Samuel A. Kotler et al.   Scientific Reports

Orientations of Residues along the β-Arch of Self-Assembled Amylin Fibril-Like Structures Lead to Polymorphism

(2014) Vered Wineman-Fisher et al.   BIOMACROMOLECULES

Molecular Characterization of the Hetero-Assembly of β-Amyloid Peptide with Islet Amyloid Polypeptide

(2014) Li-Mei Yan et al.   CURRENT PHARMACEUTICAL DESIGN

The Peculiar Role of the A2V Mutation in Amyloid-β (Aβ) 1–42 Molecular Assembly

(2014) Massimo Messa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Alzheimer Disease Protective Mutation A2T Modulates Kinetic and Thermodynamic Properties of Amyloid-β (Aβ) Aggregation

(2014) Iryna Benilova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association between Amylin and Amyloid-β Peptides in Plasma in the Context of Apolipoprotein E4 Allele

(2014) Wei Qiao Qiu et al.   PLoS One

In Silico Cross Seeding of Aβ and Amylin Fibril-like Oligomers

(2013) Workalemahu M. Berhanu et al.   ACS Chemical Neuroscience

Amylin deposition in the brain: A second amyloid in Alzheimer disease?

(2013) Kaleena Jackson et al.   ANNALS OF NEUROLOGY

Conformational Distribution and α-Helix to β-Sheet Transition of Human Amylin Fragment Dimer

(2013) Ruxi Qi et al.   BIOMACROMOLECULES

Cations as Switches of Amyloid-Mediated Membrane Disruption Mechanisms: Calcium and IAPP

(2013) Michele F.M. Sciacca et al.   BIOPHYSICAL JOURNAL

Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue

(2013) Jun-Xia Lu et al.   CELL

Familial Alzheimer A2 V Mutation Reduces the Intrinsic Disorder and Completely Changes the Free Energy Landscape of the Aβ1–28 Monomer

(2013) Phuong H. Nguyen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Molecular links between Alzheimer’s disease and diabetes mellitus

(2013) Y. Yang et al.   NEUROSCIENCE

Interactions between Aβ and Mutated Tau Lead to Polymorphism and Induce Aggregation of Aβ-Mutated Tau Oligomeric Complexes

(2013) Yoav Raz et al.   PLoS One

Lessons from two prevalent amyloidoses—what amylin and Aβ have in common

(2013) Jürgen Götz et al.   Frontiers in Aging Neuroscience

Bacterial curli protein promotes the conversion of PAP248-286into the amyloid SEVI: cross-seeding of dissimilar amyloid sequences

(2013) Kevin Hartman et al.   PeerJ

Cross-seeding and Conformational Selection between Three- and Four-repeat Human Tau Proteins

(2012) Xiang Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploring the Piezophilic Behavior of Natural Cosolvent Mixtures

(2011) Martin A. Schroer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic Interactions between Repeats in Tau Protein and Aβ Amyloids May Be Responsible for Accelerated Aggregation via Polymorphic States

(2011) Yifat Miller et al.   BIOCHEMISTRY

Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment

(2011) Ravi Prakash Reddy Nanga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Polymorphic Triple β-Sheet Structures Contribute to Amide Hydrogen/Deuterium (H/D) Exchange Protection in the Alzheimer Amyloid β42 Peptide

(2011) Buyong Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Molecular Recognition in Amyloid Growth and Transmission and Cross-Species Barriers

(2011) Buyong Ma et al.   JOURNAL OF MOLECULAR BIOLOGY

Polymorphism in Alzheimer Aβ Amyloid Organization Reflects Conformational Selection in a Rugged Energy Landscape

(2010) Yifat Miller et al.   CHEMICAL REVIEWS

Polymorphic C-terminal β-Sheet Interactions Determine the Formation of Fibril or Amyloid β-derived Diffusible Ligand-like Globulomer for the Alzheimer Aβ42 Dodecamer

(2010) Buyong Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergistic Interactions between A , Tau, and  -Synuclein: Acceleration of Neuropathology and Cognitive Decline

(2010) L. K. Clinton et al.   JOURNAL OF NEUROSCIENCE

Molecular Cross Talk between Misfolded Proteins in Animal Models of Alzheimer's and Prion Diseases

(2010) R. Morales et al.   JOURNAL OF NEUROSCIENCE

Role of Zinc in Human Islet Amyloid Polypeptide Aggregation

(2010) Jeffrey R. Brender et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hollow core of Alzheimer's A 42 amyloid observed by cryoEM is relevant at physiological pH

(2010) Y. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common features between diabetes mellitus and Alzheimer’s disease

(2009) J. Götz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Two-dimensional IR spectroscopy and isotope labeling defines the pathway of amyloid formation with residue-specific resolution

(2009) S.-H. Shim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases

(2008) Igor F. Tsigelny et al.   PLoS One

Atomic structure of the cross-β spine of islet amyloid polypeptide (amylin)

(2008) Jed J.W. Wiltzius et al.   PROTEIN SCIENCE