Article
Pediatrics
Nina Mol, Przemyslaw Tomasik, Katarzyna Klimasz, Magdalena Zasada, Przemko Kwinta
Summary: This study finds that irisin is present in infant formulas, although in lower amounts than in human milk. Further research is needed to assess whether children fed with infant formulas may suffer from a lower supply of irisin.
MINERVA PEDIATRICS
(2022)
Article
Environmental Sciences
Joaquim Rovira, Maria Angeles Martinez, Montse Mari, Sara Cristina Cunha, Jose Oliveira Fernandes, Isa Marmelo, Antonio Marques, Line Smastuen Haug, Cathrine Thomsen, Marti Nadal, Jose L. Domingo, Marta Schuhmacher
Summary: Breastfeeding is beneficial for both infants and mothers, but breast milk can contain environmental pollutants. This study measured the levels of various pollutants in the breast milk of Spanish nursing mothers and found correlations between some pollutants and maternal characteristics and smoking. Higher levels of pollutants were detected in samples from primiparous mothers and low-income mothers.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Nutrition & Dietetics
Reka A. Vass, Gabriella Kiss, Edward F. Bell, Robert D. Roghair, Attila Miseta, Jozsef Bodis, Simone Funke, Tibor Ertl
Summary: Pituitary hormones like prolactin and luteinizing hormone were found to be higher in breast milk from mothers of preterm infants compared to term infants. Infant formulas have higher total protein content but do not contain detectable levels of pituitary hormones.
Review
Food Science & Technology
Jimena Rios, Viviana Valero-Jara, Samanta Thomas-Valdes
Summary: Exclusive breastfeeding is recommended during the first 6 months of life, with breast milk composition being influenced by maternal diet. Polyphenols and carotenoids present in breast milk have antioxidant activities and potential benefits for infants, with their content depending on maternal intake and various factors. Further research is needed to understand the relationship between these phytochemicals and development of infants.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Nutrition & Dietetics
Huanmei Zhang, Xiangnan Ren, Zhenyu Yang, Jianqiang Lai
Summary: This study found that the concentration of vitamin A in healthy term human milk decreases significantly as lactation progresses. There were no significant differences in vitamin A concentration between Chinese and non-Chinese samples at each stage.
Article
Environmental Sciences
Irina Gyllenhammar, Marie Aune, Ulrika Friden, Tatiana Cantillana, Anders Bignert, Sanna Lignell, Anders Glynn
Summary: Body burdens of persistent organic pollutants (POPs) in Swedish first-time mothers were investigated through measurements in breast milk from 1996 to 2017. The trends in POPs body burdens were primarily affected by factors such as the mother's age, pre-pregnancy BMI, weight gain during pregnancy, weight loss after delivery, and education level. The levels of most organic pollutants showed a declining trend over the study period.
ENVIRONMENTAL RESEARCH
(2021)
Article
Environmental Sciences
Yukiko Fujii, Kouji H. Harada, Yoshiko Ito, Miho Yoshitake, Chiharu Matsunobu, Yoshihisa Kato, Chiho Ohta, Nobuyuki Koga, Osamu Kimura, Tetsuya Endo, Akio Koizumi, Koichi Haraguchi
Summary: This study analyzed breast milk samples collected from 10 prefectures in Japan between 2005 and 2010 to determine the concentrations of several persistent organic pollutants (POPs), including some legacy POPs and novel POPs. The results showed that different POPs exhibited different exposure routes or kinetics compared to common POPs, and there was insufficient information available for certain legacy and novel POPs.
Review
Nutrition & Dietetics
Shuchang Liu, Andrew Sharp, Elmer Villanueva, Zheng Feei Ma
Summary: This study aimed to investigate whether breast milk iodine concentration (BMIC) can be used as a biomarker for iodine status in lactating women and children under 2 years of age. The systematic review of 51 studies indicated that BMIC shows promise as a biomarker for iodine status, but interpretation should be cautious due to limitations in the included studies.
Article
Environmental Sciences
Peter Gresner, Marek Zielinski, Danuta Ligocka, Kinga Polanska, Wojciech Wasowicz, Jolanta Gromadzinska
Summary: This study analyzed the concentrations of PCDDs, PCDFs, and dl-PCBs in breast milk samples of 110 breastfeeding women from an urban area. The results showed significant correlations between dl-PCBs concentration and toxicity equivalent with mothers' age, as well as a positive association between total toxicity equivalent of all substances analyzed and the frequency of fish and dairy products consumption. These findings may provide a basis for further research on exposure to these pollutants and their mechanisms of action.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Environmental Sciences
Xiaoying Lin, Xiaoling Wu, Xiangyu Li, Duo Zhang, Quanzhi Zheng, Jiayi Xu, Shaoyou Lu
Summary: This study investigated the levels of trace elements in Chinese infant food products and found limited research on the associated risks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Medicine, Research & Experimental
Karen de Jong, David Damoiseaux, Dick Pluim, Hilde Rosing, Jos H. Beijnen, Hans van Thienen, Thomas P. C. Dorlo, Alwin D. R. Huitema, Frederic Amant
Summary: This study reports on the use of nivolumab during lactation in a woman with metastasized melanoma. It found that nivolumab accumulates in breast milk over two consecutive cycles. However, further research is needed to determine the safety of breastfeeding during nivolumab therapy.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Environmental Sciences
Marie Tysman, Jorma Toppari, Katharina M. Main, Annika Adamsson, Christine Wohlfahrt-Veje, Jean-Philippe Antignac, Bruno Le Bizec, Eliisa Loyttyniemi, Niels E. Skakkebaek, Helena E. Virtanen
Summary: Hypospadias is a congenital malformation of the penile urethra, and the etiology is mostly unknown. This study investigated the association between hypospadias and exposure to persistent organic pollutants (POPs) through breast milk. The study included Danish and Finnish mother-son pairs, and breast milk samples were analyzed for various classes of POPs. The results did not show any significant associations between POP concentrations and hypospadias in either country. This study provides information on quantitative exposures but does not support a direct link between hypospadias and POP exposure.
Article
Food Science & Technology
Kaili Wang, Xiufang Xia, Lina Sun, Hui Wang, Qiu Li, Zhuo Yang, Jing Ren
Summary: The gut microbiota is important for infants' growth and development in early life. Breast milk microbiota influences the colonization and development of the infant's gut microbiota. In this study, we examined the microbial diversity and correlation between breast milk and infant gut by sequencing the microbiome in both human milk and infant stools. The results showed the presence of certain bacteria in both breast milk and infant feces, indicating their transfer from breast milk to the infant's gut.
Review
Food Science & Technology
Marta Hernandez, Ana Juan-Garcia, Juan Carlos Molto, Jordi Manes, Cristina Juan
Summary: This review summarizes research on mycotoxin determination in infant breast milk and infant food over the past fifteen years, focusing on the population group of 1-9 months old. The findings show varying levels of mycotoxin contamination in different regions and foods, with breast milk posing the highest risk for infants within the first month of birth.
Review
Food Science & Technology
Lianghui Cheng, Renate Akkerman, Chunli Kong, Marthe T. C. Walvoort, Paul de Vos
Summary: Human milk is essential for newborn infants as it provides bioactive components like human milk oligosaccharides (hMOs) which have beneficial functions such as supporting growth of beneficial bacteria, anti-pathogenic effects, immune modulation, and stimulation of intestine barrier functions. The application of hMOs produced via genetically engineered microorganisms in infant formulas is a promising advancement in mimicking the nutritional composition of breast milk and overcoming scientific challenges.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Allergy
Hong H. T. C. Le, Pham Le An, Nguyen Nhu Vinh, Robert S. Ware, Dung Phung, Phong K. Thai, Sarath Ranganathan, Tran Ngoc Dang, Phan Hoang Thuy Dung, Do Thi Hoai Thuong, Hai Phung, To Thi Hien, Peter D. Sly
Summary: This study assessed the under-recognition of asthma in middle school children in Vietnam. The results showed that over 80% of symptomatic children were not diagnosed with asthma. Under-recognition of asthma was more common among girls. Urgent action is needed to improve the recognition of asthma in Vietnam.
Article
Engineering, Environmental
Sandra Nilsson, Jennifer Braunig, Renee N. Carey, Jennie Hui, Kayla Smurthwaite, Leisa-Maree Toms, Martyn D. Kirk, Jochen F. Mueller, Lin Fritschi
Summary: No studies have retrospectively measured PFAS concentrations in serum samples representative of a general population in Australia prior to 2000. In this study, researchers analyzed archived serum samples from 'The Busselton Health Study Data Bank'. Results showed that 13 PFAS were detected in the serum samples collected in 1975, and the PFAS serum concentrations increased significantly between 1975 and 1995, with a more than 7-fold increase in median n-ary summation PFAS serum concentration.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Respiratory System
Rachel E. Foong, Peter Franklin, Francesca Sanna, Graham L. Hall, Peter D. Sly, Eric B. Thorstensen, Dorota A. Doherty, Jeffrey A. Keelan, Roger J. Hart
Summary: This study investigated the effects of prenatal exposure to phthalates and bisphenol A (BPA) on asthma, allergy, and lung function outcomes from childhood to adulthood. The results showed that prenatal BPA exposure was associated with an increased likelihood of persistent asthma in males, while prenatal phthalate exposure was associated with an increased likelihood of adult asthma in males. However, lung function was not adversely affected by prenatal exposure to these chemicals.
Article
Nursing
M. Mamun Huda, Leonie K. Callaway, Greg Jackson, Yaqoot Fatima, Janet Cumming, Tuhin Biswas, Gonzalo R. Paz, Fran Boyle, Peter D. Sly, Abdullah Al Mamun
Summary: This study investigated the time trends, projections, and spatial distribution of low birthweight (LBW) in Australia from 2009 to 2030. The prevalence of LBW increased from 6.18% in 2009 to 6.64% in 2019. If the trend continues, the projected prevalence of LBW in Australia will reach 7.34% in 2030. The trends in LBW varied across different subpopulations, with stable rates among Indigenous mothers and increases among non-Indigenous mothers, disadvantaged mothers, and mothers who smoked during pregnancy.
BIRTH-ISSUES IN PERINATAL CARE
(2023)
Article
Environmental Sciences
Michelle Engelsman, Leisa-Maree L. Toms, Xianyu Wang, Andrew P. W. Banks
ENVIRONMENTAL RESEARCH
(2023)
Article
Medicine, Research & Experimental
Ayaho Yamamoto, Peter D. Sly, Keng Yih Chew, Lavrent Khachatryan, Nelufa Begum, Abrey J. Yeo, Luan D. Vu, Kirsty R. Short, Stephania A. Cormier, Emmanuelle Fantino
Summary: Epidemiological evidence shows a link between lower air quality and increased severity of COVID-19, but the mechanism is not yet understood. This study suggests that oxidative stress caused by air pollution could increase viral replication and inflammation in the nasal epithelium. The researchers found that exposure to an oxidant found in air pollution increased SARS-CoV-2 replication and inflammation-related gene expression, while antioxidant treatment reduced viral replication and inflammation. These findings indicate that oxidant damage to the respiratory epithelium may contribute to the association between poor air quality and increased COVID-19 severity.
EXPERIMENTAL BIOLOGY AND MEDICINE
(2023)
Article
Environmental Sciences
Hong T. M. Nguyen, Sandra Nilsson, Ava A. R. Mueller, Leisa-Maree Toms, Carl Kennedy, Daman Langguth, Peter Hobson, Jochen F. Mueller
Summary: Human biomonitoring programs have been conducted worldwide to assess the exposure and health risks of per- and polyfluoroalkyl substances (PFAS). This study provided the first evidence of PFAS exposure in the population of Papua New Guinea, a unique region both socioeconomically and geographically. The detected PFAS concentrations were lower than those in serum pools obtained from Australia, but the presence of 9Cl-F53B in all pools suggests exposure from local industrial sources.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Engineering, Environmental
Run Tian, Malte Posselt, Kathrin Fenner, Michael S. McLachlan
Summary: The environmental relevance of standard biodegradation tests, such as OECD 309, has been questioned due to challenges in interpreting degradation kinetics and the effects of chemical spiking on microbial communities. This study suggests that considering only the initial biodegradation phase can improve the environmental relevance of OECD 309.
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
(2023)
Article
Immunology
Maryam Shojaei, Amir Shamshirian, James Monkman, Laura Grice, Minh Tran, Chin Wee Tan, Siok Min Teo, Gustavo Rodrigues Rossi, Timothy R. McCulloch, Marek Nalos, Maedeh Raei, Alireza Razavi, Roya Ghasemian, Mobina Gheibi, Fatemeh Roozbeh, Peter D. Sly, Kirsten M. Spann, Keng Yih Chew, Yanshan Zhu, Yao Xia, Timothy J. Wells, Alexandra Cristina Senegaglia, Carmen Lucia Kuniyoshi, Claudio Luciano Franck, Anna Flavia Ribeiro dos Santos, Lucia de Noronha, Sepideh Motamen, Reza Valadan, Omolbanin Amjadi, Rajan Gogna, Esha Madan, Reza Alizadeh-Navaei, Liliana Lamperti, Felipe Zuniga, Estefania Nova-Lamperti, Gonzalo Labarca, Ben Knippenberg, Velma Herwanto, Ya Wang, Amy Phu, Tracy Chew, Timothy Kwan, Karan Kim, Sally Teoh, Tiana M. Pelaia, Win Sen Kuan, Yvette Jee, Jon Iredell, Ken O'Byrne, John F. Fraser, Melissa J. Davis, Gabrielle T. Belz, Majid E. Warkiani, Carlos Salomon Gallo, Fernando Souza-Fonseca-Guimaraes, Quan Nguyen, Anthony Mclean, Arutha Kulasinghe, Kirsty R. Short, Benjamin Tang
Summary: This study found that the IFI27 gene is associated with COVID-19 infection and that its expression levels in the respiratory tract and blood are correlated with viral load and infection severity. IFI27 gene family biomarkers may supplement conventional diagnostic tools in future virus pandemics.
FRONTIERS IN IMMUNOLOGY
(2023)
Editorial Material
Engineering, Environmental
Pablo Gago-Ferrero, Akhgar Ghassabian, Marja Lamoree, Leisa-Maree Toms
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Allergy
Yuan Gao, Jakob Stokholm, Martin O'Hely, Anne-Louise Ponsonby, Mimi L. K. Tang, Sarath Ranganathan, Richard Saffery, Leonard C. Harrison, Fiona Collier, Lawrence Gray, David Burgner, John Molloy, Peter D. Sly, Susanne Brix, Hanne Frokiaer, Peter Vuillermin
Summary: Having older siblings can decrease the risk of IgE-mediated food allergy by accelerating the maturation of the infant gut microbiota.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2023)
Article
Virology
Yury A. Bochkov, Mark Devries, Kaitlin Tetreault, Ronald Gangnon, Sujin Lee, Leonard B. Bacharier, William W. Busse, Carlos A. Camargo, Timothy Choi, Robyn Cohen, Ramyani De, Gregory P. DeMuri, Anne M. Fitzpatrick, Peter J. Gergen, Kristine Grindle, Rebecca Gruchalla, Tina Hartert, Kohei Hasegawa, Gurjit K. Khurana Hershey, Patrick Holt, Kiara Homil, Tuomas Jartti, Meyer Kattan, Carolyn Kercsmar, Haejin Kim, Ingrid A. Laing, Peter N. Le Souef, Andrew H. Liu, David T. Mauger, Tressa Pappas, Shilpa J. Patel, Wanda Phipatanakul, Jacqueline Pongracic, Christine Seroogy, Peter D. Sly, Christopher Tisler, Ellen R. Wald, Robert Wood, Robert F. Lemanske, Daniel J. Jackson, James E. Gern
Summary: This study examined cross-neutralization reactions and antibody duration of rhinovirus type A (RV-A) and type C (RV-C). The results showed limited cross-neutralization reactions between the two types, which are limited to genetically similar strains. However, the duration of antibody response during childhood is similar for both types.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Pediatrics
Mari D. Takashima, Keith Grimwood, Peter D. Sly, Stephen B. Lambert, Robert S. Ware
Summary: This study evaluated the interaction between rhinovirus and potentially pathogenic bacteria in early infancy and their association with wheezing and asthma. The results showed that rhinovirus infection increased the risk of wheezing before age 2 years, while Haemophilus influenzae infection increased the odds of asthma at age 5-7 years. Microbes may have an etiologic role in wheezing and asthma.
PEDIATRIC PULMONOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Dwan Vilcins, Peter Baker, Paul Jagals, Peter D. Sly
Summary: The study assessed the trends in birthweight and maternal characteristics over a 19-year period using descriptive statistics. The findings showed a decrease in average birthweight and an increase in large for gestational age births. Maternal factors such as smoking, BMI, and Indigenous status were linked to changes in birthweight and the proportion of small or large for gestational age babies. There was also an increased number of births to older women and a rise in gestational diabetes, but better care practices for women with gestational diabetes resulted in a decline in large for gestational age births.
JOURNAL OF PUBLIC HEALTH-HEIDELBERG
(2023)
Article
Pediatrics
Carla Rebeca Da Silva Sena, Matthew Morten, Adam M. Collison, Aida Shaar, Ediane de Queiroz Andrade, Joseph Meredith, Elizabeth Kepreotes, Vanessa E. Murphy, Peter D. Sly, Bruce Whitehead, Wilfried Karmaus, Peter G. Gibson, Paul D. Robinson, Joerg Mattes
Summary: Children with a history of hospital admission for RV positive bronchiolitis in infancy may have a higher risk of lung ventilation inhomogeneities at preschool age, particularly arising from the peripheral conducting airways.
PEDIATRIC PULMONOLOGY
(2023)
