Alternative splicing and the evolution of phenotypic novelty

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

(2016) Xinping Yang et al.   CELL

The ribosome-engaged landscape of alternative splicing

(2016) Robert J Weatheritt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Robust detection of alternative splicing in a population of single cells

(2016) Joshua D. Welch et al.   NUCLEIC ACIDS RESEARCH

New genes from old: asymmetric divergence of gene duplicates and the evolution of development

(2016) Peter W. H. Holland et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The complete local genotype–phenotype landscape for the alternative splicing of a human exon

(2016) Philippe Julien et al.   Nature Communications

The ribosome-engaged landscape of alternative splicing

(2016) Robert J Weatheritt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An alternative splicing program promotes adipose tissue thermogenesis

(2016) Santiago Vernia et al.   eLife

Exploration of alternative splicing events in ten different grapevine cultivars

(2015) Emilio Potenza et al.   BMC GENOMICS

Evidence for widespread subfunctionalization of splice forms in vertebrate genomes

(2015) Matthew J. Lambert et al.   GENOME RESEARCH

Why Selection Might Be Stronger When Populations Are Small: Intron Size and Density Predict within and between-Species Usage of Exonic Splice Associatedcis-Motifs

(2015) XianMing Wu et al.   MOLECULAR BIOLOGY AND EVOLUTION

Alternative Splice in Alternative Lice

(2015) Jaime M. Tovar-Corona et al.   MOLECULAR BIOLOGY AND EVOLUTION

RNA mis-splicing in disease

(2015) Marina M. Scotti et al.   NATURE REVIEWS GENETICS

Functional roles of alternative splicing factors in human disease

(2015) Benjamin Cieply et al.   Wiley Interdisciplinary Reviews-RNA

Genome-wide analysis of alternative splicing in Volvox carteri

(2015) Arash Kianianmomeni et al.   BMC GENOMICS

Building Robust Transcriptomes with Master Splicing Factors

(2014) Mohini Jangi et al.   CELL

Alternative splicing inDrosophilaneuronal development

(2014) Carmen Mohr et al.   JOURNAL OF NEUROGENETICS

Correcting for Differential Transcript Coverage Reveals a Strong Relationship between Alternative Splicing and Organism Complexity

(2014) Lu Chen et al.   MOLECULAR BIOLOGY AND EVOLUTION

A Pair of RNA-Binding Proteins Controls Networks of Splicing Events Contributing to Specialization of Neural Cell Types

(2014) Adam D. Norris et al.   MOLECULAR CELL

The human splicing code reveals new insights into the genetic determinants of disease

(2014) H. Y. Xiong et al.   SCIENCE

Fungal Alternative Splicing is Associated with Multicellular Complexity and Virulence: A Genome-Wide Multi-Species Study

(2013) K. Grutzmann et al.   DNA RESEARCH

Drift and conservation of differential exon usage across tissues in primate species

(2013) A. Reyes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative Splicing and Subfunctionalization Generates Functional Diversity in Fungal Proteomes

(2013) Alexandra N. Marshall et al.   PLoS Genetics

Revisit on the evolutionary relationship between alternative splicing and gene duplication

(2012) Zhixi Su et al.   GENE

Function of alternative splicing

(2012) Olga Kelemen et al.   GENE

Comparison of the transcriptional profiles of head and body lice

(2012) B. P. Olds et al.   INSECT MOLECULAR BIOLOGY

Tissue-Specific Alternative Splicing Remodels Protein-Protein Interaction Networks

(2012) Jonathan D. Ellis et al.   MOLECULAR CELL

Quantification of stochastic noise of splicing and polyadenylation in Entamoeba histolytica

(2012) Chung-Chau Hon et al.   NUCLEIC ACIDS RESEARCH

Evolutionary Dynamics of Gene and Isoform Regulation in Mammalian Tissues

(2012) J. Merkin et al.   SCIENCE

The Evolutionary Landscape of Alternative Splicing in Vertebrate Species

(2012) N. L. Barbosa-Morais et al.   SCIENCE

Effective/census population size ratio estimation: a compendium and appraisal

(2012) Friso P. Palstra et al.   Ecology and Evolution

The Accumulation of Gene Regulation Through Time

(2011) Maria Warnefors et al.   Genome Biology and Evolution

Increased levels of noisy splicing in cancers, but not for oncogene-derived transcripts

(2011) Lu Chen et al.   HUMAN MOLECULAR GENETICS

Functional consequences of developmentally regulated alternative splicing

(2011) Auinash Kalsotra et al.   NATURE REVIEWS GENETICS

The influence of persistent individual differences and age at maturity on effective population size

(2011) A. M. Lee et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Drift and Genome Complexity Revisited

(2011) Kenneth D. Whitney et al.   PLoS Genetics

Coding potential of the products of alternative splicing in human

(2011) Guido Leoni et al.   GENOME BIOLOGY

The relationship between proteome size, structural disorder and organism complexity

(2011) Eva Schad et al.   GENOME BIOLOGY

The calculation of information and organismal complexity

(2010) Yun Jiang et al.   Biology Direct

Age-dependent gain of alternative splice forms and biased duplication explain the relation between splicing and duplication

(2010) J. Roux et al.   GENOME RESEARCH

Evolution of alternative splicing in primate brain transcriptomes

(2010) Lan Lin et al.   HUMAN MOLECULAR GENETICS

Genotype and Tissue-Specific Effects on Alternative Splicing of the Transcription Factor 7-Like 2 Gene in Humans

(2010) Ashis K. Mondal et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Alternative Splicing of Neuroligin Regulates the Rate of Presynaptic Differentiation

(2010) H. Lee et al.   JOURNAL OF NEUROSCIENCE

Alternative Splicing and Gene Duplication in the Evolution of the FoxP Gene Subfamily

(2010) M. E. Santos et al.   MOLECULAR BIOLOGY AND EVOLUTION

A Generation Time Effect on the Rate of Molecular Evolution in Invertebrates

(2010) Jessica A. Thomas et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genome-wide analysis of alternative splicing evolution amongMussubspecies

(2010) BETTINA HARR et al.   MOLECULAR ECOLOGY

Expansion of the eukaryotic proteome by alternative splicing

(2010) Timothy W. Nilsen et al.   NATURE

Rate, molecular spectrum, and consequences of human mutation

(2010) M. Lynch   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The adaptive significance of unproductive alternative splicing in primates

(2010) A. Skandalis et al.   RNA

The Honey Bee Epigenomes: Differential Methylation of Brain DNA in Queens and Workers

(2010) Frank Lyko et al.   PLOS BIOLOGY

Noisy Splicing Drives mRNA Isoform Diversity in Human Cells

(2010) Joseph K. Pickrell et al.   PLoS Genetics

Did Genetic Drift Drive Increases in Genome Complexity?

(2010) Kenneth D. Whitney et al.   PLoS Genetics

Quantitative regulation of alternative splicing in evolution and development

(2009) Manuel Irimia et al.   BIOESSAYS

Tissue-specific alternative splicing of TCF7L2

(2009) Ludmila Prokunina-Olsson et al.   HUMAN MOLECULAR GENETICS

The pathobiology of splicing

(2009) Amanda J Ward et al.   JOURNAL OF PATHOLOGY

Cancer-associated regulation of alternative splicing

(2009) Julian P Venables et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Stochastic noise in splicing machinery

(2009) Eugene Melamud et al.   NUCLEIC ACIDS RESEARCH

Common SNPs in HMGCR in Micronesians and Whites Associated With LDL-Cholesterol Levels Affect Alternative Splicing of Exon13

(2008) Ralph Burkhardt et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genetic estimates of contemporary effective population size: what can they tell us about the importance of genetic stochasticity for wild population persistence?

(2008) FRISO P. PALSTRA et al.   MOLECULAR ECOLOGY

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS

RsiteDB: a database of protein binding pockets that interact with RNA nucleotide bases

(2008) A. Shulman-Peleg et al.   NUCLEIC ACIDS RESEARCH