Article
Environmental Sciences
Phayong Thepaksorn, Pureum Lee, Yoko Shiwaku, Bo Zheng, Akio Koizumi, Kouji H. Harada
Summary: In this study, the degradability of perfluorooctanoic acid (PFOA) and perfluorohexanoic acid in river soils was evaluated to understand their impact on perfluorocarboxylic acid (PFCA) levels in the Yodo River Basin. The influence of abiotic oxidation on PFCA formation in soils and the presence of fluorotelomer alcohols (FTOHs) as precursors were also investigated. The findings suggest that PFOA is rapidly removed from water systems but persists in soils. Evaluating FTOHs and other precursors is necessary for accurate prediction of PFCA accumulation and fate in the environment.
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Hua-Qing Yin, Kui Tan, Stephanie Jensen, Simon J. Teat, Saif Ullah, Xiuze Hei, Ever Velasco, Kolade Oyekan, Noah Meyer, Xin-Yao Wang, Timo Thonhauser, Xue-Bo Yin, Jing Li
Summary: The study introduces a luminescent MOF In(tcpp) for the sensitive detection and removal of fluoride ions (F-) and perfluorooctanoic acid (PFOA) in water, showing high selectivity, sensitivity, recyclability, and adsorption efficiency.
Article
Environmental Sciences
Wei Zheng, Lei Hu, Zekai Chen, Jun Tang, Yuliang Pan, Wende Yan, Xiaoyong Chen, Yuanying Peng, Lijun Chen
Summary: Perfluorinated compounds (PFCs) are a class of new persistent organic pollutants widely found in the environment. This study examined the effects of two typical PFCs, perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS), on the composition and diversity of soil microorganisms and the availability of soil macronutrients in urban forest ecosystems. The results showed that PFOA and PFOS application significantly increased soil nitrate and ammonium content, while total phosphorus content remained unchanged. Total potassium content decreased in PFOA treatments but increased in PFOS and PFOA-PFOS combined treatments. The dominant bacterial phylum shifted from Chloroflexi to Acidobacteria with increasing PFCs concentrations. Fungal community composition did not change significantly in response to PFCs treatments. Soil bacterial richness decreased but diversity increased, while fungal richness and diversity generally decreased with increasing PFCs concentrations. Soil fungal community was found to be more sensitive to PFCs pollutants than bacterial communities. Structural equation modeling revealed that PFCs exposure indirectly affected the diversity and richness of soil bacteria and fungi by directly impacting nitrate and ammonium content. The concentration of PFCs pollutants played a primary role in determining the composition, richness, and diversity of forest soil microbial communities.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Environmental Sciences
M. L. Brusseau, B. Guo
Summary: This research focused on the relationship between soil porewater concentrations and soil concentrations of PFAS, based on a comprehensive model. The model was validated using measured parameters and literature data, showing accurate predictions of concentration ratios. Numerical simulations demonstrated the importance of air-water interfacial adsorption for the distribution of longer-chain PFAS. It was found that PFAS soil porewater concentrations can vary from ng/L to mg/L depending on soil concentrations and site conditions.
Article
Chemistry, Analytical
Yubin Kim, Kyndal A. Pike, Rebekah Gray, Jameson W. Sprankle, Jennifer A. Faust, Paul L. Edmiston
Summary: High-resolution mass spectrometry was used to screen for emerging PFAS compounds in precipitation samples collected in the United States. Multiple new PFAS compounds were detected, with the most prevalent ones being H-PFCAs and FTCAs. The results indicate that non-standard PFAS compounds make up a significant fraction of contaminants in rainwater, particularly near localized point sources.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2023)
Article
Materials Science, Multidisciplinary
Aditya Choudhary, Dengpan Dong, Marina Tsianou, Paschalis Alexandridis, Dmitry Bedrov
Summary: This study demonstrates the use of atomistic molecular dynamics simulations to investigate the adsorption mechanism of perfluorooctanoate (PFOA) surfactant on a polymer-based network in water. The results reveal the significance of electrostatic and hydrophobic interactions in the adsorption process.
ACS MATERIALS LETTERS
(2022)
Article
Environmental Sciences
Michelle Huang, Emma Ivantsova, Isaac Konig, Neep Patel, Cole English, Christopher L. Souders II, Christopher J. Martyniuk
Summary: This study assessed the sub-lethal toxicity potential of perfluoroheptanoic acid (PFHpA) to developing zebrafish. The results showed that PFHpA was not acutely toxic to fish up to 50 μM and exposure to 200 μM PFHpA decreased ATP-linked respiration of embryos. There was no evidence for ROS induction in larvae fish exposed to 0.1 μM or 1 μM PFHpA, but exposure to PFHpA resulted in decreased levels of certain transcripts related to mitochondrial complexes.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2023)
Article
Environmental Sciences
Yuang Wei, Haibing He, Tian Han, Bao Wang, Peng Ji, Xiangzheng Wu, Jian Qian, Pengfei Shao
Summary: Through comprehensive bioinformatics analysis, the correlation between five perfluorinated compounds (PFCs) and prostate cancer was discovered, and the promotive role of perfluorooctanoic acid (PFOA) and perfluorononanoic acid (PFNA) in the growth of prostate cancer cells was verified. This study provided novel insights into the role of PFCs in prostate cancer and raised attention to the environmental association with cancer risks and progression.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Chemistry, Analytical
Hao Wang, Xing Li, Mingyuan Shao, Li Lin, Tongna Mu, Yanqin Liu
Summary: A sensitive and versatile HPLC-MS/MS method with solid phase extraction was established for the simultaneous determination of various harmful compounds in vegetable oil, showing good reproducibility.
ANALYTICAL METHODS
(2021)
Article
Multidisciplinary Sciences
Sverre Wikstroem, Ghada Hussein, Annika Lingroth Karlsson, Christian H. Lindh, Carl-Gustaf Bornehag
Summary: Many first trimester sporadic miscarriages are unexplained, and this study aimed to investigate the association between levels of Perfluoroalkyl substances (PFASs) in early pregnancy with unexplained first trimester miscarriage. The results showed a positive correlation between PFOA exposure and sporadic first trimester miscarriage, while other PFASs showed no significant association with miscarriage. This suggests a potential shared but unknown mechanism between PFOA exposure and miscarriage.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Analytical
Megumi S. Shimizu, Rosa S. Garcia, G. Brooks Avery, Robert J. Kieber, Stephen A. Skrabal, Ralph N. Mead
Summary: The distribution of PFAS sediment along a river to ocean transect was investigated, and the occurrence of replacement PFAS in sediments was highlighted for the first time. A series of compounds that may be Nafion (TM) degradation products were also detected.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2022)
Article
Environmental Sciences
Jan Ove Bustnes, Bard-Jorgen Bardsen, Dorte Herzke, Georg Bangjord, Sophie Bourgeon, Clementine Fritsch, Igor Eulaers
Summary: The concentrations of legacy organochlorines and perfluoroalkyl substances in tawny owl eggs in central Norway have shown varying trends over the past few decades. Most legacy OCs and PFOS have not reached a lower threshold with stable background levels, and voluntary elimination of perfluoroalkyl carboxylates has not resulted in declining levels in tawny owls in central Norway.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2022)
Review
Materials Science, Multidisciplinary
Rui Li, Nayarassery N. Adarsh, Hui Lu, Mario Wriedt
Summary: PFAS have gained attention due to their toxicity and widespread contamination, leading to the urgent need for efficient removal methods. Metal-organic frameworks (MOFs) show promise as adsorbents for PFAS removal, with their tunable structures and high surface areas. This review examines the application of MOFs for PFAS removal and provides insights on design strategies for next-generation MOF materials with improved removal performances.
Review
Engineering, Environmental
Jiaqing Xiong, Yushi Hou, Jiaxuan Wang, Zhe Liu, Ying Qu, Zhengyang Li, Xinhui Wang
Summary: Traditional methods and advanced treatment processes are not suitable for PFAS removal due to their poor efficiency. Membrane processes such as NF and RO can effectively remove multiple substances, are energy-saving, and show more promise for PFAS removal.
ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Hak-Hyeon Kim, Seyfollah Gilak Hakimabadi, Anh Le-Tuan Pham
Summary: The study found that Ga2O3 photocatalyst could effectively degrade Cr(vi) and 6:2 FtS, while In2O3 also showed capability in removing both substances, but at slower rates. On the other hand, poor removal of 6:2 FtS was observed with the TiO2 photocatalyst.
Article
Environmental Sciences
Ronald William Lake, Saeed Shaeri, S. T. M. L. D. Senevirathna
Summary: This study further explores the application of the parametric group method of data handling (GMDH) in rainfall modeling and prediction using publicly available temperature and rainfall data. The ordinary GMDH approaches do not provide conclusive results due to lack of consistency in coefficients of determination and analysis of variance. Therefore, an empirical assessment is conducted to explain this inconsistency and improvements such as hybridization with least square support vector machines (LSSVM), application of filters for parameter estimation, and combination with signal processing techniques are investigated.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Biochemical Research Methods
Zhuoya Li, Xinyi Huang, Xuan Wang, Jianwei Ren, Buyi Xu, Chunying Luo, Yanjun Wang, Lian Wang, Harada Kouji, Xiaoli Zou
Summary: A rapid and sensitive high-performance liquid chromatography-high-resolution orbitrap mass spectrometry method was developed for the simultaneous screening of 354 organic poisons and metabolites in blood and urine. The method showed good prospects in clinical poisoning screening and forensic toxicological identification.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Correction
Biochemical Research Methods
Zhuoya Li, Xinyi Huang, Xuan Wang, Jianwei Ren, Buyi Xu, Chunying Luo, Yanjun Wang, Lian Wang, Kouji H. Harada, Xiaoli Zou
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Letter
Medicine, General & Internal
Kouji H. Harada, Mariko Harada Sassa
ANNALS OF INTERNAL MEDICINE
(2023)
Letter
Public, Environmental & Occupational Health
Zhaoqing Lyu, Tomoko Fujitani, Kouji H. Harada
JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Immunology
Hatasu Kobayashi, Yurie Mori, Sharif Ahmed, Yuichiro Hirao, Shinya Kato, Shosuke Kawanishi, Mariko Murata, Shinji Oikawa
Summary: It is demonstrated that N-4-hydroxycytidine (NHC), a metabolite of molnupiravir, can induce Cu(II)-mediated oxidative DNA damage in isolated DNA when treated with cytidine deaminase (CDA).
JOURNAL OF INFECTIOUS DISEASES
(2023)
Letter
Virology
Kouji H. Harada, Arthit Phosri
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Environmental Sciences
Hiroaki Itoh, Kouji H. Harada, Yoshio Kasuga, Shiro Yokoyama, Hiroshi Onuma, Hideki Nishimura, Ritsu Kusama, Kazuhito Yokoyama, Jing Zhu, Mariko Harada Sassa, Teruhiko Yoshida, Shoichiro Tsugane, Motoki Iwasaki
Summary: This study investigated the association between PFASs and global DNA methylation levels in leukocytes. It found that 13 PFASs were significantly associated with increased global DNA methylation levels in leukocytes, with an increase of 1.45%-3.96% per log10-unit increase of PFAS concentration.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Biochemistry & Molecular Biology
Tetsumori Yamashima, Takuya Seike, Shinji Oikawa, Hatasu Kobayashi, Hidenori Kido, Masahiro Yanagi, Daisuke Yamamiya, Shihui Li, Piyakarn Boontem, Eishiro Mizukoshi
Summary: Alzheimer's disease, type 2 diabetes, and NASH are increasingly common disorders. Individuals with type 2 diabetes are prone to Alzheimer's disease. The pathogenesis of these disorders is multifactorial, but oxidative damage caused by reactive oxygen species (ROS) may play a common role. The lipid peroxidation product hydroxynonenal has been implicated in cell degeneration and death in the brain, pancreas, and liver.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2023)
Editorial Material
Engineering, Environmental
Sosina Walelign, Zhaoqing Lyu, Kouji H. Harada
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Fisheries
John Conallin, Nyi Nyi Tun, Aye Myint Swe, Lee J. Baumgartner, Zau Lunn, Martin Mallen-Cooper, Tim Marsden, Nathan Ning, Wayne Robinson, Lalantha Senevirathna, Peter Thew
Summary: The construction of dams and other river infrastructures is threatening the population of migratory fish species by reducing river-floodplain connectivity. Fishways are important tools for restoring river connectivity for these fishes, but their effectiveness is often limited by a lack of biological information on the target species, especially in developing countries. This study aimed to inform the design of a vertical-slot fishway for migratory fishes in Myanmar. The results showed that the ability of fish to pass through the flume was influenced by hydraulic conditions and fish size. Obtaining baseline biological information on the target species is crucial for optimizing the effectiveness of planned fishways.
FISHERIES RESEARCH
(2023)
Review
Environmental Sciences
Lalantha Senevirathna, Himali Erandathie Ratnayake, Nadeeka Jayasinghe, Jinlong Gao, Xiaoyan Zhou, Shanika Nanayakkara
Summary: Water fluoridation is a safe and effective public health strategy to improve oral health. This review provides a comprehensive summary of the available evidence on water fluoridation in Australia, including its history, health impacts, cost effectiveness, challenges, and limitations. The findings show that water fluoridation has significantly reduced dental caries in the Australian population and is considered a cost-effective intervention, although it faces challenges in terms of opposition, costs, access, communication, and ethical concerns. Overall, the review highlights the importance of ongoing monitoring and research to ensure the sustainable benefits of water fluoridation. Rating: 9/10.
ENVIRONMENTAL RESEARCH
(2023)
Article
Water Resources
Yukiko Fujii, Kouji H. Harada, Yoshihisa Kato, Osamu Kimura, Tetsuya Endo, Koichi Haraguchi
Summary: This study evaluated the regional source dietary exposure of anthropogenic organochlorine pesticides (OCPs) and halogenated natural products (HNPs) in Japan. The results showed that dicofol and endosulfan were the main OCPs, while Cl-7-MBP and Br4Cl2-DBP were the main HNPs. The exposure levels of these compounds differed from those of other OCPs and HNPs, indicating different sources. Further research is needed to identify the sources of these compounds and assess their risks to human health.
EXPOSURE AND HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Sani Rachman Soleman, Meng Li, Tomoko Fujitani, Kouji H. Harada
Summary: This study aimed to evaluate the relationship between seafood intake and exposure to per- and polyfluoroalkyl substances (PFASs) in the Japanese population. The results showed that the plasma concentrations of PFOA, PFNA, PFUnDA, and PFDoDA were significantly associated with seafood intake.
ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE
(2023)
Article
Environmental Sciences
Adrian Hickey, Lalantha Senevirathna
Summary: Climate change is causing more frequent extreme weather events, such as floods, droughts, and heatwaves, which are impacting water supply systems globally. Water agencies and utilities need to develop resilient and adaptable systems to cope with these challenges. Case studies, like the one on water quality and supply management in New South Wales, demonstrate the importance of effective water treatment processes and collaboration among local governments to ensure a secure and reliable water supply during extreme weather events.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
