Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group

CYP2C9 and CYP2C19 Allele and Haplotype Distributions in Four Mestizo Populations from Western Mexico: An Interethnic Comparative Study

(2016) Ana Miriam Saldaña-Cruz et al.   Genetic Testing and Molecular Biomarkers

Million Veteran Program: A mega-biobank to study genetic influences on health and disease

(2016) John Michael Gaziano et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Considerations for assessing the potential effects of antidiabetes drugs on cardiac ventricular repolarization: A report from the Cardiac Safety Research Consortium

(2015) Simon Heller et al.   AMERICAN HEART JOURNAL

Comprehensively Evaluating cis -Regulatory Variation in the Human Prostate Transcriptome by Using Gene-Level Allele-Specific Expression

(2015) Nicholas B. Larson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Dissecting the genetics of the human transcriptome identifies novel trait-relatedtrans-eQTLs and corroborates the regulatory relevance of non-protein coding loci

(2015) Holger Kirsten et al.   HUMAN MOLECULAR GENETICS

Diabetes

(2015) David M. Nathan   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Mortality risk among sulfonylureas: a systematic review and network meta-analysis

(2015) Scot H Simpson et al.   Lancet Diabetes & Endocrinology

Short QT in a Cohort of 1.7 Million Persons: Prevalence, Correlates, and Prognosis

(2014) Carlos Iribarren et al.   ANNALS OF NONINVASIVE ELECTROCARDIOLOGY

Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLs

(2014) Xiaoling Zhang et al.   BMC GENOMICS

Risk of Cardiac Arrhythmias During Hypoglycemia in Patients With Type 2 Diabetes and Cardiovascular Risk

(2014) Elaine Chow et al.   DIABETES

Use of Antidiabetic Drugs in the U.S., 2003–2012

(2014) Christian Hampp et al.   DIABETES CARE

CYP2C9, KCNJ11 and ABCC8 polymorphisms and the response to sulphonylurea treatment in type 2 diabetes patients

(2014) Jasna Klen et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Genetic Variants Associated With Phenytoin-Related Severe Cutaneous Adverse Reactions

(2014) Wen-Hung Chung et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

(2014) Dan E Arking et al.   NATURE GENETICS

Genome-Wide Identification of Expression Quantitative Trait Loci (eQTLs) in Human Heart

(2014) Tamara T. Koopmann et al.   PLoS One

Generalized estimating equations for genome-wide association studies using longitudinal phenotype data

(2014) Colleen M. Sitlani et al.   STATISTICS IN MEDICINE

Gene-environment interaction between SCN5A-1103Y and hypokalemia influences QT interval prolongation in African Americans: The Jackson Heart Study

(2013) Ermeg L. Akylbekova et al.   AMERICAN HEART JOURNAL

To Replicate or Not to Replicate: The Case of Pharmacogenetic Studies

(2013) Stella Aslibekyan et al.   Circulation-Cardiovascular Genetics

Cardiovascular safety of sulfonylureas: a meta-analysis of randomized clinical trials

(2013) M. Monami et al.   DIABETES OBESITY & METABOLISM

Influence of CYP2C9 and VKORC1 genotypes on the risk of hemorrhagic complications in warfarin-treated patients: A systematic review and meta-analysis

(2013) Jie Yang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Genome-wide association study of chronic periodontitis in a general German population

(2013) Alexander Teumer et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Drug–gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval

(2013) C L Avery et al.   PHARMACOGENOMICS JOURNAL

Pharmacogenomics, ancestry and clinical decision making for global populations

(2013) E Ramos et al.   PHARMACOGENOMICS JOURNAL

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Influence of CYP2C9 and VKORC1 on Patient Response to Warfarin: A Systematic Review and Meta-Analysis

(2012) Andrea L. Jorgensen et al.   PLoS One

Drug interactions with oral antidiabetic agents: pharmacokinetic mechanisms and clinical implications

(2012) Aleksi Tornio et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma

(2012) Ke Hao et al.   PLoS Genetics

QT-Interval Duration and Mortality Rate

(2011) Yiyi Zhang   ARCHIVES OF INTERNAL MEDICINE

TCF7L2 and therapeutic response to sulfonylureas in patients with type 2 diabetes

(2011) Andreas Holstein et al.   BMC Medical Genetics

Effect of genetic polymorphisms on the pharmacokinetics and efficacy of glimepiride in a Korean population

(2011) Hyun-Jung Cho et al.   CLINICA CHIMICA ACTA

Electrocardiographic QT Interval and Mortality

(2011) Yiyi Zhang et al.   EPIDEMIOLOGY

The False-positive to False-negative Ratio in Epidemiologic Studies

(2011) John P. A. Ioannidis et al.   EPIDEMIOLOGY

KCNJ11 gene E23K variant and therapeutic response to sulfonylureas

(2011) Martin Javorsky et al.   European Journal of Internal Medicine

Transethnic meta-analysis of genomewide association studies

(2011) Andrew P. Morris   GENETIC EPIDEMIOLOGY

Two-marker association tests yield new disease associations for coronary artery disease and hypertension

(2011) Thomas P. Slavin et al.   HUMAN GENETICS

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Market withdrawal of new molecular entities approved in the United States from 1980 to 2009

(2011) Zaina P. Qureshi et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Multiple Loci Are Associated with White Blood Cell Phenotypes

(2011) Michael A. Nalls et al.   PLoS Genetics

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

(2010) Nona Sotoodehnia et al.   NATURE GENETICS

Gene–environment-wide association studies: emerging approaches

(2010) Duncan Thomas   NATURE REVIEWS GENETICS

Common variation in the NOS1AP gene is associated with reduced glucose-lowering effect and with increased mortality in users of sulfonylurea

(2010) Matthijs L. Becker et al.   Pharmacogenetics and Genomics

Methodological Issues in Multistage Genome-Wide Association Studies

(2010) Duncan C. Thomas et al.   STATISTICAL SCIENCE

Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

(2009) Bruce M. Psaty et al.   Circulation-Cardiovascular Genetics

Loss-of-Function CYP2C9 Variants Improve Therapeutic Response to Sulfonylureas in Type 2 Diabetes: A Go-DARTS Study

(2009) K Zhou et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The E23K Variant ofKCNJ11and the Risk for Severe Sulfonylurea-induced Hypoglycemia in Patients with Type 2 Diabetes

(2009) A. Holstein et al.   HORMONE AND METABOLIC RESEARCH

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

(2009) Santhi K Ganesh et al.   NATURE GENETICS

Ser1369Ala Variant in Sulfonylurea Receptor Gene ABCC8 Is Associated With Antidiabetic Efficacy of Gliclazide in Chinese Type 2 Diabetic Patients

(2008) Y. Feng et al.   DIABETES CARE

Drug induced shortening of the QT/QTc interval: An emerging safety issue warranting further modelling and evaluation in drug research and development?

(2008) Mark Holbrook et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS