Article
Public, Environmental & Occupational Health
Chen Liu, Jae Hyoung Lee, Amanda J. Gupta, Austin Tucker, Chris Larkin, Patricia Turimumahoro, Achilles Katamba, J. Lucian Davis, David Dowdy
Summary: Human-centred design (HCD) is a problem-solving approach used to develop global health interventions. The cost-effectiveness of HCD depends on the number of clients reached and the trade-off between HCD costs and intervention delivery costs.
Article
Public, Environmental & Occupational Health
Matti Marklund, Leopold N. Aminde, Mary Njeri Wanjau, Liping Huang, Celine Awuor, Lindsay Steele, Laura K. Cobb, J. Lennert Veerman, Jason H. Y. Wu
Summary: This study utilizes a multiple cohort proportional multistate life table model to demonstrate the potential health gains and cost-effectiveness of implementing a mandatory limit on industrial trans fatty acids (iTFA) in Kenya. The findings suggest that such intervention could prevent ischemic heart disease (IHD) events and deaths, save healthcare costs, and be a cost-saving strategy in the long term.
Article
Medicine, General & Internal
Wenru Shang, Yang Wan, Jianan Chen, Yanqiu Du, Jiayan Huang
Summary: The study compared the health economic value of NIPT strategy against STS strategy for Down syndrome detection in China. Introducing NIPT strategies was found to be more beneficial than using STS alone, with evaluating maternal age in combination with NIPT outperforming China's current referral strategy in terms of cost-effectiveness and safety. Lowering the price of NIPT and optimizing payment methods are effective measures to promote universal NIPT strategies in China.
Article
Medicine, General & Internal
David Livingstone Ejalu, Aaron Irioko, Rhoda Kirabo, Aggrey David Mukose, Elizabeth Ekirapa, Joseph Kagaayi, Juliana Namutundu
Summary: This study investigated the cost-effectiveness of Xpert Omni compared with Xpert MTB/Rif for diagnosing tuberculosis in a low-resource, high burden facility. The results showed that Xpert Omni was more effective but more expensive than Xpert MTB/Rif when used at a point-of-care health facility.
Article
Medicine, General & Internal
Mizan Kiros, Solomon Tessema Memirie, Mieraf Taddesse Taddesse Tolla, Michael Tekle Palm, Daniel Hailu, Ole F. Norheim
Summary: The study aims to estimate the cost-effectiveness of running a pediatric oncology unit in Ethiopia to provide decision support for the revision of the Ethiopia Essential Health Service Package (EEHSP). A decision tree model was used to compare the cost and effectiveness of running a pediatric oncology unit with no pediatric oncology care. The results showed that the incremental cost and DALYs averted per child treated in the pediatric oncology unit were USD 876 and 2.4, respectively. The incremental cost-effectiveness ratio was USD 361 per DALY averted, indicating that running a pediatric oncology unit is cost-effective in Ethiopia.
Article
Public, Environmental & Occupational Health
Sirpa Heinavaara, Andrea Gini, Tytti Sarkeala, Ahti Anttila, Harry de Koning, Iris Lansdorp-Vogelaar
Summary: This study modeled the cost-effectiveness of sex-specific FIT screening strategies in Finland and evaluated the optimal strategies. The results showed that annual FIT screening with a cut-off of 25μg/g for men aged 50-79 and with a cut-off of 10μg/g for women aged 55-69 was optimal. This strategy significantly reduced the incidence and mortality of colorectal cancer.
PREVENTIVE MEDICINE
(2022)
Article
Medicine, General & Internal
Dimitra Panagiotoglou, Michal Abrahamowicz, David L. Buckeridge, J. Jaime Caro, Eric Latimer, Mathieu Maheu-Giroux, Erin C. Strumpf
Summary: This study aims to conduct a comprehensive cost-effectiveness analysis of harm reduction interventions for people who inject drugs, taking into account the prevention of skin, soft tissue and vascular infections, as well as anoxic/toxicity-related brain injury, in addition to traditional measures of benefit such as HIV, hepatitis C, and overdose morbidity and mortalities averted.
Article
Medicine, General & Internal
Hamidah Hussain, Amyn Malik, Junaid F. Ahmed, Sara Siddiqui, Farhana Amanullah, Jacob Creswell, Thorkild Tylleskar, Bjarne Robberstad
Summary: The study found that enhanced and active approaches to contact investigation effectively identify additional patients with TB among household contacts at a relatively modest cost. These strategies can be added to passive contact investigation in high burden settings to reach the people with TB who are missed and achieve the goals of the End TB strategy.
Article
Medicine, General & Internal
Kevin Duan, Francisco Rodriguez Garza, Hugo Flores, Daniel Palazuelos, Jimena Maza, Luis Alberto Martinez-Juarez, Patrick F. Elliott, Elena Moreno Lazaro, Natan Enriquez Rios, Gustavo Nigenda, Lindsay Palazuelos, Ryan K. McBain
Summary: CESPEC is a cost-effective community-based model of diabetes care for patients in rural Mexico, providing more health-adjusted years at a lower cost compared to usual care.
Article
Medicine, General & Internal
Evans Otieku, Ama Pokuaa Fenny, Felix Ankomah Asante, Antoinette Bediako-Bowan, Ulrika Enemark
Summary: This study assesses the cost-effectiveness of an active 30-day surgical site infection (SSI) surveillance mechanism at a teaching hospital in Ghana. The results show that the intervention significantly reduces the risk and costs associated with SSI, making it a simple, cost-effective, sustainable, and adaptable strategy.
Article
Public, Environmental & Occupational Health
Ana-Catarina Pinho-Gomes, Alec Knight, Julia Critchley, Mark Pennington
Summary: Most adults in England do not consume the recommended five portions of fruit and vegetables per day, leading to a significant number of deaths and healthcare costs. Subsidizing fruit and vegetable consumption through various policies can increase intake and reduce disease burden, with targeted subsidies for low-income households being the most likely cost-effective option.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2021)
Article
Oncology
Antoine Eskander, Kathryn E. Marqueen, Heather A. Edwards, Anthony M. Joshua, Teresa M. Petrella, John R. de Almeida, David P. Goldstein, Bart S. Ferket
Summary: The study found that banning tanning bed use by adolescents can prevent melanoma cases, reduce healthcare costs, and improve cost-effectiveness. Even after considering the costs of implementing the ban and the economic losses in the indoor-tanning industry, banning tanning bed use by adolescents may still be considered a cost-effective strategy.
Article
Otorhinolaryngology
Joseph R. Acevedo, Jeffrey C. Yu, Brian Cameron, Margaret Nurimba, Joel W. Hay, Niels C. Kokot
Summary: This cost-effectiveness analysis compared reconstruction methods after salvage total laryngectomy, revealing primary closure as the most cost-effective choice. However, conclusions were sensitive to the health utilities of each reconstruction method, highlighting the importance of careful consideration when advising patients on their options.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2021)
Article
Medicine, General & Internal
Yashika Chugh, Madhumita Premkumar, Gagandeep Singh Grover, Radha K. Dhiman, Yot Teerawattananon, Shankar Prinja
Summary: The study suggests that implementing a one-time universal screening followed by treatment for HCV infected individuals in Punjab, India, is a cost-effective strategy when compared to no screening policy. However, the budget impact of screening all individuals >= 18 years old may be unsustainable. Therefore, the recommendation is to start with screening the age cohort of 40-45 years old with rapid diagnostic tests (RDT) based on both cost-effectiveness and budget impact findings.
Review
Medicine, General & Internal
Constantine Vardavas, Katerina Nikitara, Konstantinos Zisis, Konstantinos Athanasakis, Revati Phalkey, Jo Leonardi-Bee, Helen Johnson, Svetla Tsolova, Massimo Ciotti, Jonathan E. Suk
Summary: This study conducted a systematic review of econometric analyses on respiratory infectious disease outbreaks occurring between 2003 and 2019. The results showed that the economic burden of these outbreaks was significant, with indirect costs outweighing direct costs mainly due to productivity losses. Non-pharmaceutical strategies such as prehospitalisation screening and the use of protective masks were found to be effective and cost-saving.